The information stored in the DNA sequence of the genome is the basis of the proper functioning of physiological processes. Certain variants, inherited or acquired, of the DNA sequence alter this information and thus are associated with malfunctions, often leading to disease. Identification of such DNA variants therefore is pivotal for a better understanding of human disease. The Institute for Functional Gene Analysis (IFGA) uses modern high-throughput sequencing technology (Next Generation Sequencing, NGS) to achieve this aim. Our mission is to identify novel DNA sequence variants within genes relevant to various biomedical questions and to elucidate their functional consequences on a molecular level.
IFGA instrument for Next Generation Sequencing (NGS)