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Research at the university

Research Database: Projects

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Research Projects (183)

ROSE3D - Robust and Safe 3D Camera System

The aim of the project is to develop a new system approach for optical 3D imaging cameras that combines different measurement approaches in an extended measurement architecture and thus overcomes the current limitations of today's 3D cameras. The technology to be developed should enable robust and safe operation, especially in functional safety applications. To this end, the measuring range and robustness in the detection of fast movements are to be improved compared to the state of the art. The planned basic technology is the ToF camera method (time-of-flight method). FKZ: 13FH554KX1

Project management at the H-BRS

Prof. Dr Robert Lange Prof. Dr Norbert Jung
MigrAVE

In the MigrAVE project, the objective is to develop supporting technologies for children diagnosed with Autism Spectrum Disorder (ASD). ASD is a disorder that leads to behavioural and social challenges for those affected, for instance difficulty recognising emotions, general inability to act appropriately in everyday social situations, or repetitive behaviours. Early treatment of ASD could mitigate the effects of the disorder and improve the quality of life of affected people.

Project management at the H-BRS

Professor im Ruhestand / retired professor Dr. Paul G. Plöger
Aminoacylases (Deficiencies of Aminoacylase 1 and of Aspartoacylase/ Canavan Disease)

Our research group studies rare genetic defects in metabolic pathways. We are aiming at a better understanding of pathomechanisms underlying such inborn errors of metabolism. Many metabolic diseases result in early death or severe handicaps if they are not treated in an adequate manner. Early diagnosis is a prerequisite for therapeutic approaches, which may enable normal development in some of those diseases.

Project management at the H-BRS

Prof. Dr Jörn Oliver Sass
Ketone bodies: More than just energy carriers! (KETOplus)

So called ketone bodies acetoacetic acid and (R)-3-hydroxy-n-butyric acid (bOHB) are compounds which provide the brain with fatty acid-derived energy, mainly after fasting. In recent years it has become obvious that ketone bodies can have more biological functions than just being energy carriers. Our project is devoted to such roles of ketone bodies that may also be important for pathogenesis and treatment of diseases.

Project management at the H-BRS

Prof. Dr Jörn Oliver Sass
Analysis platform for molecular mechanisms and cellular functions

An analysis platform consisting of four components offers a significant expansion of biomedical analysis possibilities at Hochschule Bonn-Rhein-Sieg (H-BRS). A binding analysis device based on microscaled thermophoresis contributes an innovative approach to characterising interactions involving proteins. A multi-mode detection device for UV/Vis, fluorescence and luminescence allows, among other things, a variety of enzyme activity tests and imaging studies in new or improved form. An automated patch clamp system and a system for solid-supported membrane (SSM)-based electrophysiology for high-resolution transporter studies provide the equipment basis for expanding research into membrane transport processes and other molecular mechanisms of disease development.

Project management at the H-BRS

Prof. Dr Jörn Oliver Sass
Amino acid N-Acyltransferases in Human Metabolism

Our research group studies rare genetic defects in metabolic pathways. We are aiming at a better understanding of pathomechanisms underlying such inborn errors of metabolism. We continuously offer internships and thesis projects focused on analytical biochemistry (for example on the development of diagnostic tests) and on the characterization of metabolic diseases. Phase 2 reactions increase the water solubility of compounds and thus facilitate their excretion. This can be achieved by conjugation of a coenzyme A (coA)-activated acid for instance with an amino acid molecule.

Project management at the H-BRS

Prof. Dr Jörn Oliver Sass
Inborn Errors of Metabolism: Disorders of the catabolism of branched-chain amino acids and D-glycerate kinase deficiency

Our research group studies rare genetic defects in metabolic pathways. We are aiming at a better understanding of pathomechanisms underlying such inborn errors of metabolism (IEM). Many metabolic diseases result in early death or severe handicaps if they are not treated in an adequate manner. Early diagnosis is a prerequisite for therapeutic approaches, which may enable normal development in some of those diseases.

Project management at the H-BRS

Prof. Dr Jörn Oliver Sass
Cyber Security Learning Lab - High-security and emergency response

Information and communication technologies (ICT) have become part of our everyday life and it is almost impossible to imagine life without them. Reason for that is the increasing digitalization of our world. Especially in our economic sector ICTs are one of the most driving factors for innovation and therefore strongly responsible forthe competitiveness of many companies. But ICTs not only influence our lives within economy, they also shape our society e.g. in authorities.

Project management at the H-BRS

Prof. Dr Karl Jonas
IR and ToF measurement and algorithms for automatic signal evaluation for a mobile vehicle classification system (RaIT vehicle classification)

Cities and municipalities must create the right framework conditions for road traffic so that it is compatible for everyone from an ecological, economic and social point of view. To ensure this, precise measurements of traffic volumes and a classification of road users are required.

Project management at the H-BRS

Prof. Dr Jürgen Apfelbeck Prof. Dr Robert Lange Prof. Dr Robert Scholl
FunForGen

Individual variants in the DNA sequence (i.e. the linear sequence of the 4 DNA building blocks, the so-called bases) are called polymorphisms and can influence the function of genes and thus contribute to the clinical manifestation of diseases or influence their course and therapy. In addition, polymorphism patterns can be so characteristic for each individual that they also enable the forensic identification of perpetrators and victims on the basis of a DNA trace.

Project management at the H-BRS

Prof. Dr Richard Jäger

Contact Points

Centre for Science and Technology Transfer (ZWT)

Room

F 405

Address

Grantham-Allee 20

53757, Sankt Augustin

Telephone

+49 2241 865 745

Vice President for Research and Young Academics

Campus

Sankt Augustin

Address

Grantham-Allee 20

53757, Sankt Augustin

Telephone

+49 2241 865 602