Our research group studies rare genetic defects in metabolic pathways. We are aiming at a better understanding of pathomechanisms underlying such inborn errors of metabolism. We continuously offer internships and thesis projects focused on analytical biochemistry (for example on the development of diagnostic tests) and on the characterization of metabolic diseases. Phase 2 reactions increase the water solubility of compounds and thus facilitate their excretion. This can be achieved by conjugation of a coenzyme A (coA)-activated acid for instance with an amino acid molecule.

Project management at the H-BRS