Department of Natural Sciences

Clinical Chemistry (MSc)

Lecture

Compulsory course

in MSc Biomedical Sciences, 2^nd semester
6h/week (2L/2E/2P)
Credits: 8 ECTS

Learning outcomes:

After completing this module students are able to read and evaluate laboratory result sheets of routine laboratories and to interpret and question potential errors / limitations occurring during (pre-)analysis.
They know exemplary physiologic and pathological alterations of main analytes of human organs as well as typical laboratory results of selected relevant human diseases, the basics of (pre-)analytics and how to interpret and statistically quality control the results of analyses derived from human matrices such as whole blood, plasma, serum, and urine.

Download scripts, group assignment etc. (LEA)

Exercises

Content:

In the seminar they have learned how to work out the most widely used Clinical Chemistry analytical methods such as laboratory automation, (immuno-) turbidometry, photospectrometry, nephelometry, EIA, enzyme-activity-assays, iso-enzyme quantitation, serum electrophoresis, urine microscopy, HPLC, realtime PCR, modern sequencing etc.
presentation of their findings to the fellows in an oral presentation
Basics and concepts in Clinical Chemistry and laboratory analytical methods as well as anatomical /medical basic principles influencing laboratory main analytes, as measured from human matrices, will be communicated.

Internship

This practical course contributes to learning fundamentals in Clinical Chemistry. Students get hands-on experience in exemplary assays.
The methods underlying the tests need to be understood as well as the meaning of the results.

Requirements

1) The result of a written exam, which is based on lecture, exercise and practical class, will yield 100% of the final mark, if exercise (2) and practical class (3) are both passed. (If one of them is not passed, the student has failed the entire module.)

2) Oral presentation during an exercise session is mandatory, as is the submission of a two-page hand-out.

3) Active full-time participation in all four events of the practical course is also a requirement, as is the submission of a protocol via LEA prior to the deadline which is indicated in the module announcement.

Literature

Information on helpful literature will be provided in the lecture.