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Institute for Functional Gene Analytics (IFGA)

Student Theses

Bachelor, Master and PhD theses completed at IFGA
  1. Sarah Heß. PhD Thesis. Optimierung von STR-Profilen aus telogenen Einzelhaaren. Supervisor: Prof Richard Jäger


  1. Sara-Sophie Poethe. Bachelor Thesis. Validation of a method using Illumina Next Generation Sequencing for forensic DNA typing. Supervisor: Prof Richard Jäger
  2. Sandra Eickert. Bachelor Thesis. Identification of sequence variants of the human OXCT2 gene by Next Generation Sequencing (NGS) of DNA.  Supervisors: Prof Jörn Oliver Sass, Prof Richard Jäger
  3. Mishell Montserratt García Villamarín. Bachelor Thesis. Characterization of High and Low Biomass Environmental Samples by 16S and ITS Targeted Amplicon Sequencing. Supervisor: Prof Martin Sieber
  4. Richard Tillmann. Bachelor Thesis. Establishment of Long-Range PCR assays for Next Generation Sequencing based Analysis of Parkinson Disease related Human Solute Carrier Genes. Supervisor: Prof Richard Jäger
  5. Susanne Kurz. BSc Thesis. Glutarylation in Glutaric Aciduria Type 1. Supervisor: Prof Jörn Oliver Sass
  6. Chantal Schmitt. BSc Thesis. Exploration of Enzymes involved in Ketone Body Metabolism. Supervisor: Prof Jörn Oliver Sass


  1. Jasmin Ewert. Bachelor Thesis. Establishment of a Long-Range PCR based NGS Assay for High Throughput Sequencing of the Human Parkinson’s Disease associated Transporter Genes SLC6A3 and SLC22A3.  Supervisors: Prof. Dr. Richard Jäger, Prof. Dr. Walter Witke.
  2. Arthur Cleal. Bachelor Thesis. Quantitative PCR based analysis of DNA degradation. Supervisor: Prof. Dr. Richard Jäger.
  3. Rahinat Muhammad. Bachelor Thesis. The exploration of long-range polymerase chain reaction and next-generation sequencing procedures for the detection of mutations in the MPV17 gene. Supervisors: Prof. Dr. Hans Weiher.
  4. Anna Mona Rosendahl. Bachelor Thesis. Optimization of Loci Balance for Short Tandem Repeat Analysis by Next Generation Sequencing. Supervisor: Prof. Dr. Richard Jäger.
  5. Yuleisy Lucrecia Whilby Hall. Bachelor Thesis. Development and Realisation of a Clinical Trial Regarding the Effect of Herbal Mouthwash with Antibacterial Properties for the Oral Microbiome of Healthy Subjects. Supervisor: Prof. Martin Sieber.
  6. Glenn MG Theunissen. PhD Thesis. DNA profiling of single sperm cells and single skin flakes using micromanipulation and whole genome amplification. Supervisor: Prof. Dr. Richard Jäger.
  7. Nina Wetzig. Bachelor Thesis. Taxonomiebasierte statistische Mikrobiomanalyse auf Basis von NGS Daten. Supervisor: Prof. Dr. Ralf Thiele.
  8. Sonia Aktar. MSc Thesis. Bi-allelic co-expression of selected sequence variants in the ASPA gene for the study of compound heterozygosity. Supervisor: Prof. Jörn Oliver Sass
  9. Annika Brimmers. BSc Thesis. Research on human ketone body utilization: expressing and characterizing isoforms and mutants of succinyl-coenzyme A : 3-oxoacid coenzyme A transferase. Supervisor: Prof. Jörn Oliver Sass
  10. Jana Caroline Hollenbeck. BSc Thesis. Aminoacylase 1 in Huntington disease. Supervisor: Prof. Jörn Oliver Sass
  11. Enise Kumas. BSc Thesis. Assessment of 3-hydroxy-2-methylbutyryl-coenzyme A dehydrogenase in human cells. Supervisor: Prof. Jörn Oliver Sass
  12. Viktoria Pasareva. MSc Thesis. Overexpression, Purification and Characterization of the Endoprotease Activity and Kinetics of Human Aminoacylase 3. Supervisor: Prof. Jörn Oliver Sass
  13. Imke von Stülpnagel. BSc Thesis. Partial Characterisation of recombinant human Glycine N-acyltransferase-like protein 2 and the influence of sequence variation on enzyme activity. Supervisor: Prof. Jörn Oliver Sass
  14. Tamara Wied. BSc Thesis. Compound Heterozygosity in Aspartoacylase Deficiency. Supervisor: Prof. Jörn Oliver Sass


  1. Maria del Mar Boronat. Bachelor Thesis. Relationship between DNA degradation and post-mortem interval. Supervisor: Prof. Dr. Richard Jäger.
  2. Adesanoye Neville Olabode. Meta-analysis of microbiome clinical trials and microbial analysis of skin and soil samples. Supervisor: Prof Martin Sieber.
  3. Simone Janik. Bachelor Thesis. Eine statistische Analyse von Mikrobiomdaten aus dem Next Generation Sequencing. Supervisor: Prof. Dr. Ralf Thiele.
  4. Sebastian Ginzel. PhD Thesis. Enabling Versatile And Comprehensive Analysis Of Genomic Variant DataSupervisor: Prof. Dr. Ralf Thiele.
  5. Rebecca Engler. BSc Thesis. Enzyme activity of sulfite oxidase in human cells. Supervisor: Prof. Jörn Oliver Sass
  6. Mhd Aghyad Al Kabbani. MSc Thesis. Purification and Characterization of Recombinant Human Acylpeptide Hydrolase. Supervisor: Prof. Jörn Oliver Sass
  7. Niloufar Mosaddeghzadeh. MSc Thesis. Assessment of Read-through drugs in Canavan disease. Supervisor: Prof. Jörn Oliver Sass


  1. Despina Yohanna Tsortouktzidis. Characterization of Acylpeptide  hydrolase (APEH) sequence variants and their potential impact on pharmacogenetics. Supervisor: Prof. Jörn Oliver Sass