Institut für funktionale Gen-Analytik (IFGA)
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Institut für funktionale Gen-Analytik (IFGA)
2025
Sezin Dagdeviren, Megan F. Hoang, Jialu Wang, Tamara Goldberger, Amelia M. Yu, Steven J. Blair, Jake C. Benoit, Elisabeth M. Ricci-Blair, Veronika Y. Melnik, Bo-Yeon Kim, Lauren A. Tauer, Julia-Josefine Scholz, Anna Worthmann, Christian Schlein, Deborah Stone, Natalie T. Deuitch, Ivona Aksentijevich, Oskar Schnappauf, Jessica L. Whited, Jason K. Kim, Richard T. Lee:
Covalent binding of thioredoxin to TXNIP is required for diet-induced insulin resistance in the liver.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.jbc.2025.110214 PMID urn:nbn:de:hbz:1044-opus-90456
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Mika Pohlen, Francesco Basile, Alexander Glassmann, Harald Illges:
Soluble CD21: From Shedding to Autoimmunity.
PDF Download (CC BY-NC 4.0) doi:10.1159/000544696 urn:nbn:de:hbz:1044-opus-90201
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Peng Chen, Yinhao Chen, Yulu Wang, Amit Sharma, Veronika Lukacs-Kornek, Hans Weiher, Maria A. Gonzalez-Carmona, Ingo G. H. Schmidt-Wolf:
Macrophage-derived pro-inflammatory cytokines augment the cytotoxicity of cytokine-induced killer cells by strengthening the NKG2D pathway in multiple myeloma.
PDF Download (CC BY 4.0) doi:10.1038/s41598-025-99289-x PMID urn:nbn:de:hbz:1044-opus-90196
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Kerri Kurkovetz, Matea Cartolano, Manuela Gebhardt, Lars E. Schumann, Stefan M. Kast, Anna Moroni, Gerhard Thiel, Oliver Rauh:
Yeast complementation assays provide limited informationon functional features of K+ channels.
PDF Download (CC BY 4.0) doi:10.1016/j.bpr.2025.100206 PMID urn:nbn:de:hbz:1044-opus-89335
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Wiebke Ewert, Christian Bartens, Jekaterina Ongouta, Monika Holmes, Anja Heutling, Anusha Kishore, Tim Urbansky, Carsten Zeilinger, Matthias Preller, Andreas Kirschning:
Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus.
PDF Download (CC BY 4.0) doi:10.1038/s41467-025-57013-3 PMID urn:nbn:de:hbz:1044-opus-89224
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Claudio Neidhöfer, Mateja Condic, Nathalie Hahn, Lucia A. Otten, Damian J. Ralser, Nina Wetzig, Ralf Thiele, Achim Hoerauf, Marijo Parčina:
Homogeneity Between Cervical and Vaginal Microbiomes and the Diagnostic Limitations of 16S Sequencing for STI Pathogens at Higher Ct Values.
PDF Download (CC BY 4.0) doi:10.3390/ijms26051983 PMID urn:nbn:de:hbz:1044-opus-89110
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Tobias Schulze, Oliver Rauh, Gerhard Thiel, Niels Fertig, Andre Bazzone, Christian Grimm:
Unraveling pH Regulation of TMEM175, an Endolysosomal Cation Channel With a Role in Parkinson's Disease.
PDF Download (CC BY 4.0) doi:10.1002/jcp.70008 urn:nbn:de:hbz:1044-opus-88785 PMID
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Oskar Schnappauf, Hongying Wang, Ivona Aksentijevich, Daniel L. Kastner, Ronald M. Laxer:
A 33-year diagnostic odyssey in an Ashkenazi Jewish patient with Aicardi-Goutières syndrome.
PDF Download (CC BY 4.0) doi:10.1016/j.jacig.2025.100400 urn:nbn:de:hbz:1044-opus-88578 PMID
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Annika Mozer, Camilla Bruno Di-Nizo, Albia Consul, Bruno Huettel, Richard Jäger, Ayodélé Akintayo, Christoph Erhardt, Lena Fenner, Dominik Fischer, Sophia Forat, France Gimnich, Peter Grobe, Sebastian Martin, Vikram Nathan, Ammar Saeed, Laura von der Mark, Christian Woehle, Klaus Olek, Bernhard Misof, Jonas J. Astrin:
FOGS: A SNPSTR Marker Database to Combat Wildlife Trafficking and a Cell Culture Bank for Ex-Situ Conservation.
PDF Download (CC BY 4.0) doi:10.1111/1755-0998.14062 PMID urn:nbn:de:hbz:1044-opus-88298
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Xiao Peng, Oskar Schnappauf, Adriana A. De Jesus, Ivona Aksentijevich:
Systemic Autoinflammatory Diseases.
doi:10.1002/9781683674023.ch70
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2024
Mo Legelli, Matti Froning, Michaela Wirtz, Stefan Lamotte:
Finding the ideal solvent for the analysis of polar analytes using supercritical fluid chromatography.
doi:10.1007/s00216-024-05647-5 PMID
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Despoina Kyriazi, Lea Voth, Almke Bader, Wiebke Ewert, Juliane Gerlach, Kerstin Elfrink, Peter Franz, Mariana I. Tsap, Bastian Schirmer, Julia Damiano-Guercio, Falk K. Hartmann, Masina Plenge, Azam Salari, Dennis Schöttelndreier, Katharina Strienke, Nadine Bresch, Claudio Salinas, Herwig O. Gutzeit, Nora Schaumann, Kais Hussein, Heike Bähre, Inga Brüsch, Peter Claus, Detlef Neumann, Manuel H. Taft, Halyna R. Shcherbata, Anaclet Ngezahayo, Martin Bähler, Mahdi Amiri, Hans-Joachim Knölker, Matthias Preller, Georgios Tsiavaliaris:
An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
PDF Download (CC BY 4.0) doi:10.1038/s41467-024-54181-6 PMID urn:nbn:de:hbz:1044-opus-87388
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Fynn Zahnow, Chiara Jaeger, Yassmin Mohamed, Gianluca Vogelhuber, Fabian May, Alexandra Maria Ciocan, Arianna Manieri, Stephan Maxeiner, Gabriela Krasteva-Christ, Matthew R.D. Cobain, Lars Podsiadlowski, Jose Luis Crespo-Picazo, Daniel Garcia-Parraga, Mike Althaus:
The evolutionary path of the epithelial sodium channel delta-subunit in Cetartiodactyla points to a role in sodium sensing.
doi:10.1101/2024.11.18.623996 PMID
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Tobias Schulze, Timon Sprave, Carolin Groebe, Jan Krumbach, Magnus Behringer, Kay Hamacher, Gerhard Thiel, Christian Grimm, Oliver Rauh:
Proton selective conductance and gating of lysosomal cation channel TMEM175.
doi:10.1101/2024.11.01.621492
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Richard Jäger:
Genomic Multicopy Loci Targeted by Current Forensic Quantitative PCR Assays.
PDF Download (CC BY 4.0) doi:10.3390/genes15101299 urn:nbn:de:hbz:1044-opus-86210 PMID
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Bernd C. Schwahn, Francjan van Spronsen, Albert Misko, Julija Pavaine, Victoria Holmes, Ronen Spiegel, Guenter Schwarz, Flora Wong, Alistair Horman, James Pitt, Jörn Oliver Sass, Charlotte Lubout:
Consensus guidelines for the diagnosis and management of isolated sulfite oxidase deficiency and molybdenum cofactor deficiencies.
PDF Download (CC BY 4.0) doi:10.1002/jimd.12730 PMID urn:nbn:de:hbz:1044-opus-82853
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Yutao Li, Amit Sharma, Michèle J. Hoffmann, Dirk Skowasch, Markus Essler, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Discovering single cannabidiol or synergistic antitumor effects of cannabidiol and cytokine-induced killer cells on non-small cell lung cancer cells.
PDF Download (CC BY 4.0) doi:10.3389/fimmu.2024.1268652 urn:nbn:de:hbz:1044-opus-80708 PMID
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Peng Chen, Amit Sharma, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Biological mechanisms and clinical significance of endoplasmic reticulum oxidoreductase 1 alpha (ERO1α) in human cancer.
PDF Download (CC BY 4.0) doi:10.1186/s13046-024-02990-4 urn:nbn:de:hbz:1044-opus-79878 PMID
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Annika Mozer, Albia Consul, Bernhard Misof, Richard Jäger, Klaus Olek, Jonas J. Astrin:
Joint detection of microsatellites and flanking sequences – SNPSTR markers for Athene noctua to fight illegal wildlife trade.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.fsiae.2024.100084 urn:nbn:de:hbz:1044-opus-77822
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Nicole Schräder, Wan Xia Zhu, Alexander Jaekel, Mo Legelli, Daniel Meyer, Kevin Streckel, Michaela Wirtz, Stefan Lamotte:
Application of Chiral Stationary Phases for the Separation of Vitamin A Acetate Isomers.
doi:10.1016/j.chroma.2024.464710 PMID
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2023
Vanessa Trindade Bortoluzzi, Rafael Teixeira Ribeiro, Camila Vieira Pinheiro, Ediandra Tissot Castro, Tailine Quevedo Tavares, Guilhian Leipnitz, Jörn Oliver Sass, Roger Frigério Castilho, Alexandre Umpierrez Amaral, Moacir Wajner:
N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential implications for the pathogenesis of ACY1 deficiency.
doi:10.1016/j.bbrc.2023.149123 PMID
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Vanessa Trindade Bortoluzzi, Rafael Teixeira Ribeiro, Ângela Beatris Zemniaçak, Sâmela de Azevedo Cunha, Jörn Oliver Sass, Roger Frigério Castilho, Alexandre Umpierrez Amaral, Moacir Wajner:
Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency.
doi:10.1016/j.neuint.2023.105631 PMID
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Gerardo A. Stoppiello, Claudia Coleine, Ralf Moeller, Caterina Ripa, Daniela Billi, Laura Selbmann:
Seasonality Is the Main Determinant of Microbial Diversity Associated to Snow/Ice around Concordia Station on the Antarctic Polar Plateau.
PDF Download (CC BY 4.0) doi:10.3390/biology12091193 urn:nbn:de:hbz:1044-opus-75251 PMID
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Jana Hinz, Tessema F. Mekonnen, Jonas Bergrath, Savanna Sewell, Yannic Schneck, Michaela Wirtz, Ursula Telgheder:
Analysis of nine nitrosamines relevant to occupational safety by ion mobility spectroscopy and preliminary gas chromatographic separation.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.jcoa.2023.100102 urn:nbn:de:hbz:1044-opus-75166
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Claudio Neidhöfer, Derick Lekealem Nkwetta, Bangsi Rose Fuen, Njodzeka Flora Yenban, Nancielle Mbiatong, Gordon Takop Nchanji, Patricia Korir, Nina Wetzig, Martin Sieber, Ralf Thiele, Marijo Parcina, Ute Klarmann-Schulz, Achim Hoerauf, Samuel Wanji, Manuel Ritter:
Tropical leg lymphedema caused by podoconiosis is associated with increased colonisation by anaerobic bacteria.
PDF Download (CC BY 4.0) doi:10.1038/s41598-023-40765-7 PMID urn:nbn:de:hbz:1044-opus-75099
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Alexander Jaekel, Mo Legelli, Michaela Wirtz, Daniel Meyer, Nicole Schräder, Kevin Streckel, Stefan Lamotte:
Selectivity optimization in liquid chromatography via stationary phase tuning.
doi:10.1002/jssc.202300204 PMID
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Alexander Perniss, Brett Boonen, Sarah Tonack, Moritz Thiel, Krupali Poharkar, Mohamad Wessam Alnouri, Maryam Keshavarz, Tamara Papadakis, Silke Wiegand, Uwe Pfeil, Katrin Richter, Mike Althaus, Johannes Oberwinkler, Burkhard Schütz, Ulrich Boehm, Stefan Offermanns, Trese Leinders-Zufall, Frank Zufall, Wolfgang Kummer:
A succinate/SUCNR1-brush cell defense program in the tracheal epithelium.
PDF Download (CC BY 4.0) doi:10.1126/sciadv.adg8842 PMID urn:nbn:de:hbz:1044-opus-74794
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Jason W. An, Pallavi Pimpale-Chavan, Deborah L. Stone, Marcia Bandeira, Fatma Dedeoglu, Jeffrey Lo, John Bohnsack, Sofia Rosenzweig, Oskar Schnappauf, Dilan Dissanayake, Linda T. Hiraki, Daniel L. Kastner, Christina Pelajo, Ronald M. Laxer, Ivona Aksentijevich:
Case report: Novel variants in RELA associated with familial Behcet's-like disease.
doi:10.3389/fimmu.2023.1127085 PMID
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A. Cassaro, C. Pacelli, M. Baqué, A. Maturilli, U. Böttger, A. Fujimori, R. Moeller, J-P P. de Vera, S. Onofri:
Spectroscopic investigations of fungal biomarkers after exposure to heavy ion irradiation.
doi:10.1016/j.saa.2023.123073 PMID
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Claudio Neidhöfer, Maria Bagniceva, Nina Wetzig, Martin A. Sieber, Ralf Thiele, Marijo Parčina:
Pragmatic Considerations When Extracting DNA for Metagenomics Analyses of Clinical Samples.
PDF Download (CC BY 4.0) doi:10.3390/ijms241411262 urn:nbn:de:hbz:1044-opus-73988 PMID
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Kira Billinger, Charles A. Okai, Manuela Russ, Cornelia Koy, Claudia Röwer, Kwabena F. M. Opuni, Harald Illges, Ulrich Pecks, Michael O. Glocker:
Dried serum spots on pre-punched filter paper discs are ready-to-use storage and shipping devices for blood-borne antigens and antibodies.
PDF Download (CC BY 4.0) doi:10.1016/j.jim.2023.113519 PMID urn:nbn:de:hbz:1044-opus-73977
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Alexander Jaekel, Michaela Wirtz, Stefan Lamotte, Mo Legelli:
Performance in (Ultra-)high-performance liquid chromatography-How to qualify and optimize instruments in practice.
doi:10.1002/jssc.202200894 PMID
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Richard Jäger:
Special Issue on Whole Genome Amplification.
PDF Download (CC BY 4.0) doi:10.3390/ijms24119626 urn:nbn:de:hbz:1044-opus-72954 PMID
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Rene Y. Lawong, Fabian May, Etang C. Etang, Philipp Vorrat, Jonas George, Julia Weder, Dagmar Kockler, Matthias Preller, Mike Althaus:
Recording Sodium Self-Inhibition of Epithelial Sodium Channels Using Automated Electrophysiology in Xenopus Oocytes.
PDF Download (CC BY 4.0) doi:10.3390/membranes13050529 urn:nbn:de:hbz:1044-opus-70317 PMID
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Claudia Fagliarone, Claudia Mosca, Giorgia Di Stefano, Stefan Leuko, Ralf Moeller, Elke Rabbow, Petra Rettberg, Daniela Billi:
Enabling deep-space experimentations on cyanobacteria by monitoring cell division resumption in dried Chroococcidiopsis sp. 029 with accumulated DNA damage.
PDF Download (CC BY 4.0) doi:10.3389/fmicb.2023.1150224 urn:nbn:de:hbz:1044-opus-70297 PMID
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Claudio Neidhöfer, Kamni Rathore, Marijo Parčina, Martin A. Sieber:
ESKAPEE Pathogen Biofilm Control on Surfaces with Probiotic Lactobacillaceae and Bacillus species.
PDF Download (CC BY 4.0) doi:10.3390/antibiotics12050871 urn:nbn:de:hbz:1044-opus-70179 PMID
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Mike Althaus, Diego Alvarez de la Rosa, Martin Fronius:
ENaC channels.
doi:10.1201/9781003096276-21
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Stephan Maxeiner, Gabriela Krasteva-Christ, Mike Althaus:
Pitfalls of using sequence databases for heterologous expression studies - a technical review.
PDF Download (CC BY-NC 4.0) doi:10.1113/JP284066 PMID urn:nbn:de:hbz:1044-opus-67145
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Mateja Condic, Claudio Neidhöfer, Damian J. Ralser, Nina Wetzig, Ralf Thiele, Martin Sieber, Lucia A. Otten, Leonie K. Warwas, Achim Hoerauf, Alexander Mustea, Marijo Parčina:
Analysis of the cervical microbiome in women from the German national cervical cancer screening program.
PDF Download (CC BY 4.0) doi:10.1007/s00432-023-04599-0 PMID urn:nbn:de:hbz:1044-opus-66298
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Sara-Sophie Poethe, Julia Holtel, Jan-Philip Biermann, Trine Riemer, Melanie Grabmüller, Burkhard Madea, Ralf Thiele, Richard Jäger:
Cost-Effective Next Generation Sequencing-Based STR Typing with Improved Analysis of Minor, Degraded and Inhibitor-Containing DNA Samples.
PDF Download (CC BY 4.0) doi:10.3390/ijms24043382 urn:nbn:de:hbz:1044-opus-66045 PMID
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Stefan Kühn, Monray E. Williams, Marli Dercksen, Jörn Oliver Sass, Rencia van der Sluis:
The glycine N-acyltransferases, GLYAT and GLYATL1, contribute to the detoxification of isovaleryl-CoA - an in-silico and in vitro validation.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.csbj.2023.01.041 urn:nbn:de:hbz:1044-opus-66037 PMID
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Claudio Neidhöfer, Esther Sib, Al-Harith Benhsain, Christina Mutschnik-Raab, Anna Schwabe, Alexander Wollkopf, Nina Wetzig, Martin A. Sieber, Ralf Thiele, Manuel Döhla, Steffen Engelhart, Nico T. Mutters, Marijo Parčina:
Examining Different Analysis Protocols Targeting Hospital Sanitary Facility Microbiomes.
PDF Download (CC BY 4.0) doi:10.3390/microorganisms11010185 urn:nbn:de:hbz:1044-opus-65910 PMID
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Alessandro Napoli, Claudia Coleine, Nikea J. Ulrich, Ralf Moeller, Daniela Billi, Laura Selbmann:
Snow Surface Microbial Diversity at the Detection Limit within the Vicinity of the Concordia Station, Antarctica.
PDF Download (CC BY 4.0) doi:10.3390/life13010113 urn:nbn:de:hbz:1044-opus-65655 PMID
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Jörn Oliver Sass, Daniel Schulke:
Intracellular localization of Glycine N-acyltransferase-like protein 1 (GLYATL1).
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JinHeng Lin, Sean M. Gettings, Khaoula Talbi, Rainer Schreiber, Michael J. Taggart, Matthias Preller, Karl Kunzelmann, Mike Althaus, Michael A. Gray:
Pharmacological inhibitors of the cystic fibrosis transmembrane conductance regulator exert off-target effects on epithelial cation channels.
PDF Download (CC BY 4.0) doi:10.1007/s00424-022-02758-9 PMID urn:nbn:de:hbz:1044-opus-64572
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2022
Daniel Schulke, Jana C. Hollenbeck, Lil Klaas, Jörn Oliver Sass:
Funktionale Gen-Analytik: Angeborenen Stoffwechselstörungen auf der Spur.
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Karyl S. Barron, Ivona Aksentijevich, Natalie T. Deuitch, Deborah L. Stone, Patrycja Hoffmann, Ryan Videgar-Laird, Ariane Soldatos, Jenna Bergerson, Camilo Toro, Cornelia Cudrici, Michele Nehrebecky, Tina Romeo, Anne Jones, Manfred Boehm, Jennifer A. Kanakry, Dimana Dimitrova, Katherine R. Calvo, Hawwa Alao, Devika Kapuria, Gil Ben-Yakov, Dominique C. Pichard, Londa Hathaway, Alessandra Brofferio, Elisa McRae, Natalia Sampaio Moura, Oskar Schnappauf, Sofia Rosenzweig, Theo Heller, Edward W. Cowen, Daniel L. Kastner, Amanda K. Ombrello:
The Spectrum of the Deficiency of Adenosine Deaminase 2: An Observational Analysis of a 60 Patient Cohort.
doi:10.3389/fimmu.2021.811473 PMID
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Natalie T. Deuitch, Dan Yang, Pui Y. Lee, Xiaomin Yu, Natalia Sampaio Moura, Oskar Schnappauf, Amanda K. Ombrello, Deborah Stone, Hye Sun Kuehn, Sergio D. Rosenzweig, Patrycja Hoffmann, Cornelia Cudrici, Deborah M. Levy, Elizabeth Kessler, Jennifer B. Soep, Arielle D. Hay, Austin Dalrymple, Yu Zhang, Li Sun, Qiuye Zhang, Xuemei Tang, Yuan Wu, Koneti Rao, Haibo Li, Hong Luo, Yao Zhang, Jon M. Burnham, Manfred Boehm, Karyl Barron, Daniel L. Kastner, Ivona Aksentijevich, Qing Zhou:
TNF inhibition in vasculitis management in adenosine deaminase 2 deficiency (DADA2).
doi:10.1016/j.jaci.2021.10.030 PMID
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Nina Grünen, Richard Jäger, Greg Shealy, Marco Schäfer, Wolfgang Peter:
The secret life of HLA-H: Changing the paradigm.
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Catriona M. H. Anderson, Noel Edwards, Andrew K. Watson, Mike Althaus, David T. Thwaites:
Reshaping the Binding Pocket of the Neurotransmitter:Solute Symporter (NSS) Family Transporter SLC6A14 (ATB0,+) Selectively Reduces Access for Cationic Amino Acids and Derivatives.
PDF Download (CC BY 4.0) doi:10.3390/biom12101404 urn:nbn:de:hbz:1044-opus-64519 PMID
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Ying Zhang, Xiaolong Wu, Amit Sharma, Hans Weiher, Matthias Schmid, Glen Kristiansen, Ingo G. H. Schmidt-Wolf:
Anti-CD40 predominates over anti-CTLA-4 to provide enhanced antitumor response of DC-CIK cells in renal cell carcinoma.
PDF Download (CC BY 4.0) doi:10.3389/fimmu.2022.925633 urn:nbn:de:hbz:1044-opus-64181 PMID
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Lu Fan, Anusha Kishore, Linda Jansen-Olliges, Dahua Wang, Frank Stahl, Olympia Ekaterini Psathaki, Jennifer Harre, Athanasia Warnecke, Julia Weder, Matthias Preller, Carsten Zeilinger:
Identification of a Thyroid Hormone Binding Site in Hsp90 with Implications for Its Interaction with Thyroid Hormone Receptor Beta.
PDF Download (CC BY-NC-ND 4.0) doi:10.1021/acsomega.2c02331 PMID urn:nbn:de:hbz:1044-opus-64102
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Alexander Jaekel, Michaela Wirtz, Stefan Lamotte, Mortimer Legelli:
Leistungssteigerung in der HPLC: Wie Kapillaren und Partikeltechnologie das Chromatogramm verbessern.
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A. Cassaro, C. Pacelli, M. Baqué, A. Maturilli, U. Boettger, R. Moeller, A. Fujimori, J-P.P. de Vera, S. Onofri:
Nucleic acids and melanin pigments after exposure to high doses of gamma rays: a biosignature robustness test.
doi:10.1017/S1473550422000180
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Lu Fan, Athanasia Warnecke, Julia Weder, Matthias Preller, Carsten Zeilinger:
Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site.
PDF Download (CC BY 4.0) doi:10.3390/ijms23137150 PMID urn:nbn:de:hbz:1044-opus-62922
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Luis Zea, Samuel S. Piper, Hamid Gaikani, Mina Khoshnoodi, Tobias Niederwieser, Alex Hoehn, Mike Grusin, Jim Wright, Pamela Flores, Kristine Wilson, Ariana Lutsic, Louis Stodieck, Christopher E. Carr, Ralf Moeller, Corey Nislow:
Experiment verification test of the Artemis I ‘Deep Space Radiation Genomics’ experiment.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.actaastro.2022.06.018 urn:nbn:de:hbz:1044-opus-62918
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Richard Jäger:
New Perspectives for Whole Genome Amplification in Forensic STR Analysis.
PDF Download (CC BY 4.0) doi:10.3390/ijms23137090 urn:nbn:de:hbz:1044-opus-62826 PMID
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Yutao Li, Amit Sharma, Xiaolong Wu, Hans Weiher, Dirk Skowasch, Markus Essler, Ingo G. H. Schmidt-Wolf:
A Combination of Cytokine-Induced Killer Cells With PD-1 Blockade and ALK Inhibitor Showed Substantial Intrinsic Variability Across Non-Small Cell Lung Cancer Cell Lines.
PDF Download (CC BY 4.0) doi:10.3389/fonc.2022.713476 urn:nbn:de:hbz:1044-opus-62446 PMID
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Florin Sasarman, Sacha Ferdinandusse, David S. Sinasac, Ernest Fung, Rebecca Sparkes, Melanie Reeves, Catherine Rombough, Jörn Oliver Sass, Renate Voit, Jos P. N. Ruiter, Janet Koster, Hans R. Waterham, Elisabetta Pasquini, Maria A. Donati, Thorsten Marquardt, Ronald J. A. Wanders, Walla Al-Hertani:
3-Hydroxyisobutyric Acid Dehydrogenase Deficiency: Expanding the Clinical Spectrum and Quantitation of D- and L-3-Hydroxyisobutyric Acid by an LC-MS/MS Method.
doi:10.1002/jimd.12486 PMID
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Jörn Oliver Sass, Sarah C. Grünert:
Disorders of Ketone Body Metabolism and Transport.
doi:10.1007/978-3-030-67727-5_50
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Nicola Longo, Jörn Oliver Sass, Agnieszka Jurecka, Jerry Vockley:
Biomarkers for drug development in propionic and methylmalonic acidemias.
PDF Download (CC BY-ND 4.0) doi:10.1002/jimd.12478 PMID urn:nbn:de:hbz:1044-opus-60770
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Ida Romano, Carlo Camerlingo, Lisa Vaccari, Giovanni Birarda, Annarita Poli, Akira Fujimori, Maria Lepore, Ralf Moeller, Paola Di Donato:
Effects of Ionizing Radiation and Long-Term Storage on Hydrated vs. Dried Cell Samples of Extremophilic Microorganisms.
PDF Download (CC BY 4.0) doi:10.3390/microorganisms10010190 urn:nbn:de:hbz:1044-opus-60767 PMID
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Mike Althaus, Rene Yufenyuy Lawong:
Proteolytic ENaC activation in health and disease—a complicated puzzle.
PDF Download (CC BY 4.0) doi:10.1007/s00424-021-02644-w PMID urn:nbn:de:hbz:1044-opus-60084
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2021
Marcela A. Ferrada, Keith A. Sikora, Yiming Luo, Kristina V. Wells, Bhavisha Patel, Emma M. Groarke, Daniela Ospina Cardona, Emily Rominger, Patrycja Hoffmann, Mimi T. Le, Zuoming Deng, Kaitlin A. Quinn, Emily Rose, Wanxia L. Tsai, Gustaf Wigerblad, Wendy Goodspeed, Anne Jones, Lorena Wilson, Oskar Schnappauf, Ryan S. Laird, Jeff Kim, Clint Allen, Arlene Sirajuddin, Marcus Chen, Massimo Gadina, Katherine R. Calvo, Mariana J. Kaplan, Robert A. Colbert, Ivona Aksentijevich, Neal S. Young, Sinisa Savic, Daniel L. Kastner, Amanda K. Ombrello, David B. Beck, Peter C. Grayson:
Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS.
doi:10.1002/art.41743 PMID
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Justin Taft, Michael Markson, Diana Legarda, Roosheel Patel, Mark Chan, Louise Malle, Ashley Richardson, Conor Gruber, Marta Martín-Fernández, Grazia M. S. Mancini, Jan A. M. van Laar, Philomine van Pelt, Sofija Buta, Beatrijs H. A. Wokke, Ira K. D. Sabli, Vanessa Sancho-Shimizu, Pallavi Pimpale Chavan, Oskar Schnappauf, Raju Khubchandani, Müşerref Kasap Cüceoğlu, Seza Özen, Daniel L. Kastner, Adrian T. Ting, Ivona Aksentijevich, Iris H. I. M. Hollink, Dusan Bogunovic:
Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death.
doi:10.1016/j.cell.2021.07.026 PMID
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Ivona Aksentijevich, Oskar Schnappauf:
Molecular mechanisms of phenotypic variability in monogenic autoinflammatory diseases.
doi:10.1038/s41584-021-00614-1 PMID
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Oskar Schnappauf, Liane Heale, Dilan Dissanayake, Wanxia L. Tsai, Massimo Gadina, Thomas L. Leto, Daniel L. Kastner, Harry L. Malech, Douglas B. Kuhns, Ivona Aksentijevich, Ronald M. Laxer:
Homozygous variant p. Arg90His in NCF1 is associated with early-onset Interferonopathy: a case report.
doi:10.1186/s12969-021-00536-y PMID
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Oskar Schnappauf, Natalia Sampaio Moura, Ivona Aksentijevich, Monique Stoffels, Amanda K. Ombrello, Patrycja Hoffmann, Karyl Barron, Elaine F. Remmers, Michael Hershfield, Susan J. Kelly, David Cuthbertson, Simon Carette, Sharon A. Chung, Lindsy Forbess, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Carol A. McAlear, Paul A. Monach, Larry Moreland, Christian Pagnoux, Philip Seo, Jason M. Springer, Antoine G. Sreih, Kenneth J. Warrington, Steven R. Ytterberg, Daniel L. Kastner, Peter C. Grayson, Peter A. Merkel:
Sequence-Based Screening of Patients With Idiopathic Polyarteritis Nodosa, Granulomatosis With Polyangiitis, and Microscopic Polyangiitis for Deleterious Genetic Variants in ADA2.
doi:10.1002/art.41549 PMID
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Kevin E. Glinton, Anna C. E. Hurst, Kevin M. Bowling, Ingrid Cristian, Devon Haynes, Dusit Adstamongkonkul, Oskar Schnappauf, David B. Beck, Carole Brewer, Aditi Shah Parikh, Deepali N. Shinde, Alan Donaldson, Ariel Brautbar, Saskia Koene, Arie van Haeringen, Amélie Piton, Yline Capri, Margherita Furlan, Elena Gardella, Rikke Steensbjerre Møller, Irma van de Beek, Linda Zuurbier, Phillis Lakeman, Allan Bayat, Julian Martinez, Rebecca Signer, Pernille M. Torring, Morten Buch Engelund, Karen W. Gripp, Louise Amlie-Wolf, Lindsay B. Henderson, Alina T. Midro, Eugeniusz Tarasów, Beata Stasiewicz-Jarocka, Diana Moskal-Jasinska, Paul Vos, Felix Boschann, Corinna Stoltenburg, Oliver Puk, Inger-Lise Mero, Kristine Lossius, Cyril Mignot, Boris Keren, Johanna C. Acosta Guio, Ignacio Briceño, Alberto Gomez, Yaping Yang, Pawel Stankiewicz:
Phenotypic expansion of the BPTF-related neurodevelopmental disorder with dysmorphic facies and distal limb anomalies.
doi:10.1002/ajmg.a.62102 PMID
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Ying Zhang, Amit Sharma, Hans Weiher, Matthias Schmid, Glen Kristiansen, Ingo G. H. Schmidt-Wolf:
Clinical Studies on Cytokine-Induced Killer Cells: Lessons from Lymphoma Trials.
PDF Download (CC BY 4.0) doi:10.3390/cancers13236007 urn:nbn:de:hbz:1044-opus-60290 PMID
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Déborah Mathis, Jörn Oliver Sass, Claudia Graubner, Angelika Schoster:
Diagnosis of atypical myopathy based on organic acid and acylcarnitine profiles and evolution of biomarkers in surviving horses.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.ymgmr.2021.100827 urn:nbn:de:hbz:1044-opus-60155 PMID
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Patrick Werner, Wolfgang Heiden, Ernst Kruijff, Andre Hinkenjann:
Deep Learning in Mobile Sketch-Based Modelling.
doi:10.1109/ICECCME52200.2021.9590888
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Glenn M. G. Theunissen, Andrew Gibb, Paul Kong Thoo Lin, Burkhard Rolf, Sophia Forat, Richard Jäger:
DNA profiling of single sperm cells after whole genome amplification.
PDF Download (CC BY-NC-ND 4.0) doi:10.1016/j.fsir.2021.100240 urn:nbn:de:hbz:1044-opus-59674
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Zeshan P. Sheikh, Matthias Wulf, Søren Friis, Mike Althaus, Timothy Lynagh, Stephan A. Pless:
The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs.
PDF Download (CC BY-NC-SA 4.0) doi:10.1085/jgp.202112899 PMID urn:nbn:de:hbz:1044-opus-59623
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Xiaolong Wu, Amit Sharma, Johannes Oldenburg, Hans Weiher, Markus Essler, Dirk Skowasch, Ingo G. H. Schmidt-Wolf:
NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation.
PDF Download (CC BY 4.0) doi:10.3389/fimmu.2021.731767 urn:nbn:de:hbz:1044-opus-59548 PMID
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Corinna Melanie Held, Anic Guebelin, Andreas Krebs, Jörn Oliver Sass, Michael Wurm, Ekkehart Lausch, Natascha van der Werf-Grohmann, Karl Otfried Schwab:
Screening for hypophosphatasia: does biochemistry lead the way?.
doi:10.1515/jpem-2021-0104 PMID
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Sean M. Gettings, Stephan Maxeiner, Maria Tzika, Matthew R. D. Cobain, Irina Ruf, Fritz Benseler, Nils Brose, Gabriela Krasteva-Christ, Greetje Vande Velde, Matthias Schönberger, Mike Althaus:
Two Functional Epithelial Sodium Channel Isoforms Are Present in Rodents despite Pronounced Evolutionary Pseudogenization and Exon Fusion.
PDF Download (CC BY 4.0) doi:10.1093/molbev/msab271 PMID urn:nbn:de:hbz:1044-opus-58483
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S. Grünert, W. Foster, A. Schumann, L. Allan, C. Pontes, S. Roloff, N. Weinhold, W. Yue, A. AlAsmari, O. Obaid, E. Faqeih, L. Stübbe, R. Yamamoto, C. Gemperle-Britschgi, M. Walter, U. Spiekerkoetter, S. Mackinnon, J. Sass:
The clinical spectrum and molecular heterogeneity of Succinyl- CoA:3-oxoacid coenzyme A transferase (SCOT) deficiency.
URL
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D. Schulke, J. Sass:
Frequent sequence variants of human glycine N-acyltransferase (GLYAT) and inborn errors of metabolism.
URL
BibTeX | RIS
A. Schumann, K. Schaller, V. Belche, M. Cybulla, S. Grünert, N. Moers, J. Sass, A. Kaech, L. Hannibal, U. Spiekerkötter:
Impact of Fabry disease on mitochondrial homeostasis in renal epithelial cells.
URL
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Claudia Pacelli, Alessia Cassaro, Loke M. Siong, Lorenzo Aureli, Ralf Moeller, Akira Fujimori, Igor Shuryak, Silvano Onofri:
Insights into the Survival Capabilities of Cryomyces antarcticus Hydrated Colonies after Exposure to Fe Particle Radiation.
PDF Download (CC BY 4.0) doi:10.3390/jof7070495 PMID urn:nbn:de:hbz:1044-opus-56309
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Melanie Meyer, Jana C. Hollenbeck, Janine Reunert, Anja Seelhöfer, Stephan Rust, Manfred Fobker, Saskia Biskup, Ulrike Och, Mechthild Linden, Jörn Oliver Sass, Thorsten Marquardt:
3-Hydroxyisobutyrate Dehydrogenase (HIBADH) deficiency - a novel disorder of valine metabolism.
PDF Download (CC BY-NC-ND 4.0) doi:10.1002/jimd.12410 PMID urn:nbn:de:hbz:1044-opus-56230
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Alisa Förster, Frank Brand, Rouzbeh Banan, Robert Hüneburg, Christine A. M. Weber, Wiebke Ewert, Jessica Kronenberg, Christopher Previti, Natalie Elyan, Ulrike Beyer, Helge Martens, Bujung Hong, Jan H. Bräsen, Andreas Erbersdobler, Joachim K. Krauss, Martin Stangel, Amir Samii, Stephan Wolf, Matthias Preller, Stefan Aretz, Bettina Wiese, Christian Hartmann, Ruthild G. Weber:
Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin.
PDF Download (CC BY 4.0) doi:10.1007/s00401-021-02307-1 PMID urn:nbn:de:hbz:1044-opus-53988
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Thomas Gerlach, Lukas Schauer, Michael Rademacher, Wolfgang Heiden, Karl Kirschner:
Customized Software Environment for Remote Learning: Providing Students a Specialized Learning Experience.
doi:10.26434/chemrxiv.14356970.v1
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Anke Schumann, Kristin Schaller, Véronique Belche, Markus Cybulla, Sarah C. Grünert, Nicolai Moers, Jörn O. Sass, Andres Kaech, Luciana Hannibal, Ute Spiekerkoetter:
Defective lysosomal storage in Fabry Disease modifies mitochondrial structure, metabolism and turnover in renal epithelial cells.
PDF Download (CC BY-NC-ND 4.0) doi:10.1002/jimd.12373 PMID urn:nbn:de:hbz:1044-opus-53487
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Sarah C. Grünert, William Foster, Anke Schumann, Allan Lund, Christina Pontes, Sylvia Roloff, Natalie Weinhold, Wyatt W. Yue, Ali AlAsmari, Osama A. Obaid, Eissa Ali Faqeih, Lisa Stübbe, Raina Yamamoto, Corinne Gemperle-Britschgi, Melanie Walter, Ute Spiekerkötter, Sabrina Mackinnon, Jörn Oliver Sass:
Succinyl-CoA:3-oxoacid coenzyme A transferase (SCOT) deficiency: A rare and potentially fatal metabolic disease.
doi:10.1016/j.biochi.2021.02.003 PMID
BibTeX | RIS
Richard Jäger, Hans Weiher:
DNA Sequencing.
BibTeX | RIS
Richard Jäger, Hans Weiher:
Polymerase Chain Reaction.
BibTeX | RIS
Hans Weiher:
Hybridization of Nucleic Acids.
BibTeX | RIS
Hans Weiher:
Chromatography and Electrophoresis of Nucleic Acids.
BibTeX | RIS
Hans Weiher:
Isolation of DNA and RNA.
BibTeX | RIS
Patrick Forny, Friederike Hörster, Diana Ballhausen, Anupam Chakrapani, Kimberly A. Chapman, Carlo Dionisi-Vici, Marjorie Dixon, Sarah C. Grünert, Stephanie Grunewald, Goknur Haliloglu, Michel Hochuli, Tomas Honzik, Daniela Karall, Diego Martinelli, Femke Molema, Jörn Oliver Sass, Sabine Scholl-Bürgi, Galit Tal, Monique Williams, Martina Huemer, Matthias R. Baumgartner:
Guidelines for the diagnosis and management of methylmalonic acidaemia and propionic acidaemia: First revision.
PDF Download (CC BY-NC-ND 4.0) doi:10.1002/jimd.12370 PMID urn:nbn:de:hbz:1044-opus-53336
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Daniel Schulke, Jörn Oliver Sass:
Frequent sequence variants of human glycine N-acyltransferase (GLYAT) and inborn errors of metabolism.
doi:10.1016/j.biochi.2021.02.002 PMID
BibTeX | RIS
Jörn Oliver Sass, Sarah C. Grünert:
Impaired ketone body utilisation as a cause of life-threatening ketoacidosis.
doi:10.1136/postgradmedj-2021-139710 PMID
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Peter Franz, Wiebke Ewert, Matthias Preller, Georgios Tsiavaliaris:
Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and Pi Release.
PDF Download (CC BY 4.0) doi:10.3390/ijms22010104 PMID urn:nbn:de:hbz:1044-opus-52802
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Iram J. Haq, Mike Althaus, Aaron Ions Gardner, Hui Ying Yeoh, Urjita Joshi, Vinciane Saint-Criq, Bernard Verdon, Jennifer Townshend, Christopher O'Brien, Mahfud Ben-Hamida, Matthew Thomas, Stephen Bourke, Peter van der Sluijs, Ineke Braakman, Chris Ward, Michael A. Gray, Malcolm Brodlie:
Clinical and molecular characterization of the R751L-CFTR mutation.
PDF Download (CC BY 4.0) doi:10.1152/ajplung.00137.2020 PMID urn:nbn:de:hbz:1044-opus-52631
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Sarah Aurora Heß, Salvatore Trapani, Maria del Mar Boronat, Glenn M. G. Theunissen, Burkhard Rolf, Richard Jäger:
Ribosomal DNA as target for the assessment of DNA degradation of human and canine DNA.
doi:10.1016/j.legalmed.2020.101819 PMID
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Matthew D. Benson, David J. A. Plemel, Paul R. Freund, James R. Lewis, Jörn Oliver Sass, Luzy Bähr, Corinne Gemperle-Britschgi, Patrick Ferreira, Ian M. MacDonald:
Severe retinal degeneration in a patient with Canavan disease.
doi:10.1080/13816810.2020.1827441 PMID
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2020
Meera C. Viswanathan, William Schmidt, Peter Franz, Michael J. Rynkiewicz, Christopher S. Newhard, Aditi Madan, William Lehman, Douglas M. Swank, Matthias Preller, Anthony Cammarato:
A role for actin flexibility in thin filament-mediated contractile regulation and myopathy.
doi:10.1038/s41467-020-15922-5 PMID
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Oskar Schnappauf:
Genetische Diagnostik autoinflammatorischer Erkrankungen.
doi:10.1007/s00393-020-00847-7 PMID
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Oskar Schnappauf, Ivona Aksentijevich:
Mendelian diseases of dysregulated canonical NF-κB signaling: From immunodeficiency to inflammation.
doi:10.1002/JLB.2MR0520-166R PMID
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Oskar Schnappauf, Qing Zhou, Natalia Sampaio Moura, Amanda K. Ombrello, Drew G. Michael, Natalie Deuitch, Karyl Barron, Deborah L. Stone, Patrycja Hoffmann, Michael Hershfield, Carolyn Applegate, Hans T. Bjornsson, David B. Beck, P. Dane Witmer, Nara Sobreira, Elizabeth Wohler, John A. Chiorini, The American Genome Center, Clifton L. Dalgard, Nih Intramural Sequencing Center, Daniel L. Kastner, Ivona Aksentijevich:
Deficiency of Adenosine Deaminase 2 (DADA2): Hidden Variants, Reduced Penetrance, and Unusual Inheritance.
doi:10.1007/s10875-020-00817-3 PMID
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Oskar Schnappauf, Amanda K. Ombrello, Daniel L. Kastner:
Deficiency of adenosine deaminase 2: Is it an elephant after all?.
doi:10.1016/j.jaci.2020.04.023 PMID
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Andreas Krebs, Andreas Baum, Jürgen Doerfer, Klaus Gempel, Michael Wurm, Corinna Brichta, Jörn Oliver Sass, Karl Winkler, Karl Otfried Schwab:
Short-Term Effects of Growth Hormone on Lipolysis, Glucose and Amino Acid Metabolism Assessed in Serum and Microdialysate of Healthy Young Men.
doi:10.1055/a-1027-6620 PMID
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Lorenzo Aureli, Claudia Pacelli, Alessia Cassaro, Akira Fujimori, Ralf Moeller, Silvano Onofri:
Iron Ion Particle Radiation Resistance of Dried Colonies of Cryomyces antarcticus Embedded in Martian Regolith Analogues.
PDF Download (CC BY 4.0) doi:10.3390/life10120306 urn:nbn:de:hbz:1044-opus-52481 PMID
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Vincenzo Zammuto, Maria G. Rizzo, Laura M. de Plano, Domenico Franco, Salvatore Guglielmino, Maria T. Caccamo, Salvatore Magazù, Akira Fujimori, Angelina Lo Giudice, Mauro Guglielmin, Kevin Roderick McAlpin, Ralf Moeller, Concetta Gugliandolo:
Effects of Heavy Ion Particle Irradiation on Spore Germination of Bacillus spp. from Extremely Hot and Cold Environments.
PDF Download (CC BY 4.0) doi:10.3390/life10110264 urn:nbn:de:hbz:1044-opus-50997 PMID
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Wiebke Ewert, Peter Franz, Georgios Tsiavaliaris, Matthias Preller:
Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke.
PDF Download (CC BY 4.0) doi:10.3390/ijms21197417 urn:nbn:de:hbz:1044-opus-50854 PMID
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Eugenia V. Díez García de Olalla, Francesca Garofano, Hans Weiher, Michael Muders, Sarah Förster, Ingo G. H. Schmidt-Wolf:
Presence of the Transmembrane Protein Neuropilin in Cytokine-induced Killer Cells.
doi:10.21873/anticanres.14560 PMID
BibTeX | RIS
Mohamed A. Elmonem, Amaya Belanger-Quintana, Andrea Bordugo, Ritma Boruah, Elisenda Cortès-Saladelafont, Mounika Endrakanti, Pilar Giraldo, Sarah Catharina Grünert, Neerja Gupta, Madhulika Kabra, Ina Knerr, Johannes Krämer, Alice Kuster, Elena Levtchenko, Lock-Hock Ngu, M. Mar Rovira-Remisa, Jörn Oliver Sass, Jolanta Sykut-Cegielska, Albina Tummolo, Lambertus P. van den Heuvel:
The impact of COVID-19 pandemic on the diagnosis and management of inborn errors of metabolism: A global perspective.
doi:10.1016/j.ymgme.2020.09.004 PMID URL
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Boris Hespeels, Sébastien Penninckx, Valérie Cornet, Lucie Bruneau, Cécile Bopp, Véronique Baumlé, Baptiste Redivo, Anne-Catherine Heuskin, Ralf Moeller, Akira Fujimori, Stephane Lucas, Karine van Doninck:
Iron Ladies – How Desiccated Asexual Rotifer Adineta vaga Deal With X-Rays and Heavy Ions?.
PDF Download (CC BY 4.0) doi:10.3389/fmicb.2020.01792 urn:nbn:de:hbz:1044-opus-50194 PMID
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Lukas Wichmann, Mike Althaus:
Evolution of epithelial sodium channels: current concepts and hypotheses.
doi:10.1152/ajpregu.00144.2020 PMID
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Claudia Pacelli, Alessia Cassaro, Lorenzo Aureli, Ralf Moeller, Akira Fujimori, Silvano Onofri:
The Responses of the Black Fungus Cryomyces Antarcticus to High Doses of Accelerated Helium Ions Radiation within Martian Regolith Simulants and Their Relevance for Mars.
PDF Download (CC BY 4.0) doi:10.3390/life10080130 urn:nbn:de:hbz:1044-opus-50124 PMID
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Jörn Oliver Sass:
Labordiagnostik bei angeborenen Stoffwechselstörungen.
doi:10.1007/s00112-020-00938-4
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Mojgan Naghizadeh Dehno, Yutao Li, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer.
PDF Download (CC BY 4.0) doi:10.3390/ijms21093078 PMID urn:nbn:de:hbz:1044-opus-49031
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Sarah C. Grünert, Jörn Oliver Sass:
2-methylacetoacetyl-coenzyme A thiolase (beta-ketothiolase) deficiency: one disease - two pathways.
PDF Download (CC BY 4.0) doi:10.1186/s13023-020-01357-0 urn:nbn:de:hbz:1044-opus-48946 PMID
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Karl N. Kirschner, Javed Razzaq, Rudolf Berrendorf, Wolfgang Heiden:
Conformations and three-dimensional structures of selected SARS-CoV-2 drug candidates.
PDF Download (CC BY 4.0) doi:10.26434/chemrxiv.12058959 URL urn:nbn:de:hbz:1044-opus-48776
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Sarah C. Grünert, Jörn Oliver Sass:
3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: one disease - many faces.
PDF Download (CC BY 4.0) doi:10.1186/s13023-020-1319-7 urn:nbn:de:hbz:1044-opus-47684 PMID
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Karl N. Kirschner, Dirk Reith, Wolfgang Heiden:
The performance of Dunning, Jensen, and Karlsruhe basis sets on computing relative energies and geometries.
doi:10.1080/1539445x.2020.1714656
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Jörn Oliver Sass, Sidney Behringer, Malkanthi Fernando, Elisabetta Cesaroni, Ida Cursio, Alberto Volpini, Claudia Till:
d-Glycerate kinase deficiency in a neuropediatric patient.
doi:10.1016/j.braindev.2019.11.008 PMID
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2019
Oskar Schnappauf, Ivona Aksentijevich:
Current and future advances in genetic testing in systemic autoinflammatory diseases.
doi:10.1093/rheumatology/kez294 PMID
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Oskar Schnappauf, Jae Jin Chae, Daniel L. Kastner, Ivona Aksentijevich:
The Pyrin Inflammasome in Health and Disease.
doi:10.3389/fimmu.2019.01745 PMID
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Jason Liebowitz, David B. Hellmann, Oskar Schnappauf:
Thirty Years of Followup in 3 Patients with Familial Polyarteritis Nodosa due to Adenosine Deaminase 2 Deficiency.
doi:10.3899/jrheum.180820 PMID
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Honglin Feng, Noel Edwards, Catriona M. H. Anderson, Mike Althaus, Rebecca P. Duncan, Yu-Ching Hsu, Charles W. Luetje, Daniel R. G. Price, Alex C. C. Wilson, David T. Thwaites:
Trading amino acids at the aphid-Buchnera symbiotic interface.
doi:10.1073/pnas.1906223116 PMID
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Lukas Wichmann, Jasdip Singh Dulai, Jon Marles-Wright, Stephan Maxeiner, Pawel Piotr Szczesniak, Ivan Manzini, Mike Althaus:
An extracellular acidic cleft confers profound H+-sensitivity to epithelial sodium channels containing the δ-subunit in Xenopus laevispH-sensitivity of Xenopus δ-ENaC.
doi:10.1074/jbc.RA119.008255 PMID
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Monika I. Hollenhorst, Innokentij Jurastow, Rajender Nandigama, Silke Appenzeller, Lei Li, Joerg Vogel, Stephanie Wiederhold, Mike Althaus, Martin Empting, Janine Altmueller, Anna K. H. Hirsch, Veit Flockerzi, Brendan J. Canning, Antoine-Emmanuel Saliba, Gabriela Krasteva-Christ:
Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling.
doi:10.1096/fj.201901314RR PMID
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Jessica I. Hoell, Sebastian Ginzel, Michaela Kuhlen, Andreas Kloetgen, Michael Gombert, Ute Fischer, Daniel Hein, Salih Demir, Martin Stanulla, Martin Schrappe, Udo Zur Stadt, Peter Bader, Florian Babor, Friedhelm Schuster, Brigitte Strahm, Julia Alten, Anja Moericke, Gabriele Escherich, Arend von Stackelberg, Ralf Thiele, Alice C. McHardy, Christina Peters, Beat Bornhauser, Jean-Pierre Bourquin, Stefan Krause, Juergen Enczmann, Lüder Hinrich Meyer, Cornelia Eckert, Arndt Borkhardt, Roland Meisel:
Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets.
doi:10.1182/bloodadvances.2019000051 PMID
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Sarah Aurora Heß, Jan-Philip Biermann, Melanie Grabmüller, Burkhard Madea, Ralf Thiele, Richard Jäger:
Evaluation of STR profiles of single telogen hairs using probabilistic methods.
doi:10.1016/j.fsigss.2019.10.049
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David Stahl, Andrew J. Gentles, Ralf Thiele, Ines Gütgemann:
Prognostic profiling of the immune cell microenvironment in Ewing´s Sarcoma Family of Tumors.
doi:10.1080/2162402x.2019.1674113 PMID
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Maria Fitria Setiawan, Oliver Rudan, Annabelle Vogt, Maria A. Gonzalez-Carmona, Bettina Langhans, Roland Schmidt-Wolf, Francesca Garofano, Christian P. Strassburg, Juan J. Lasarte, Noelia Casares, Teresa Lozano, Hans Weiher, Ingo G. H. Schmidt-Wolf:
FOXP3 Inhibitory Peptide P60 Increases Efficacy of Cytokine-induced Killer Cells Against Renal and Pancreatic Cancer Cells.
doi:10.21873/anticanres.13730 PMID
BibTeX | RIS
Despina Tsortouktzidis, Kathleen Grundke, Claudia Till, Anne Korwitz-Reichelt, Jörn Oliver Sass:
Acylpeptide hydrolase (APEH) sequence variants with potential impact on the metabolism of the antiepileptic drug valproic acid.
doi:10.1007/s11011-019-00470-9 PMID
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Bright D. Danquah, Claudia Röwer, Kwabena F. M. Opuni, Reham El-Kased, David Frommholz, Harald Illges, Cornelia Koy, Michael O. Glocker:
Intact Transition Epitope Mapping - Targeted High-Energy Rupture of Extracted Epitopes (ITEM-THREE).
PDF Download (CC BY-NC-ND 4.0) doi:10.1074/mcp.RA119.001429 PMID urn:nbn:de:hbz:1044-opus-45635
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D. Stahl, R. Thiele, A. J. Gentles, S. Schönberger, G. Kristiansen, I. Gütgemann:
Prognostic profiling of the immune cell microenvironment in Ewing sarcoma/PNET.
URL
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S. Roloff, L. Stübbe, C. Gemperle-Britschgi, R. Yamamoto, J. Hennermann, N. Weinhold, J. O. Sass:
Disorders of ketone body transport and utilization as a cause of recurrent metabolic acidosis: succinyl-coenzyme A: 3-oxoacyl coenzyme A transferase (SCOT) deficiency (mutations in the OXCT1 gene) and monocarboxylate transporter 1 (MCT1) deficiency.
URL
BibTeX | RIS
Jörn Oliver Sass, Ina Knerr:
Aspartoacylase Deficiency (Canavan Disease, N-Acetylaspartic Aciduria).
doi:10.1007/978-981-13-2977-7_2
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Sema Safi, David Frommholz, Susanne Reimann, Werner Götz, Christoph Bourauel, Anna-Lena Neumann, Achim Hoerauf, Harald Illges, Ali-Farid Safi, Andreas Jäger, Marc P. Hübner, Lina Gölz:
Comparative study on serum-induced arthritis in the temporomandibular and limb joint of mice.
doi:10.1111/1756-185X.13486 PMID
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Maja Dembic, Henriette S. Andersen, Jean Bastin, Thomas K. Doktor, Thomas J. Corydon, Jörn Oliver Sass, Alexandra Lopes Costa, Fatima Djouadi, Brage S. Andresen:
Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease.
doi:10.1016/j.ymgme.2018.10.004 PMID
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2018
Pui Y. Lee, Yuelong Huang, Qing Zhou, Oskar Schnappauf, Michael S. Hershfield, Ying Li, Nancy J. Ganson, Natalia Sampaio Moura, Ottavia M. Delmonte, Scellig S. Stone, Michael J. Rivkin, Sung-Yun Pai, Todd Lyons, Robert P. Sundel, Victor W. Hsu, Luigi D. Notarangelo, Ivona Aksentijevich, Peter A. Nigrovic:
Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2.
doi:10.1016/j.jaci.2018.05.038 PMID
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Chrissy Kandel, Patricia Schmidt, Alexander Perniss, Maryam Keshavarz, Paul Scholz, Sabrina Osterloh, Mike Althaus, Wolfgang Kummer, Klaus Deckmann:
ENaC in Cholinergic Brush Cells.
doi:10.3389/fcell.2018.00089 PMID
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Cassie R. Bakshani, Ana L. Morales-Garcia, Mike Althaus, Matthew D. Wilcox, Jeffrey P. Pearson, John C. Bythell, J. Grant Burgess:
Evolutionary conservation of the antimicrobial function of mucus: a first defence against infection.
doi:10.1038/s41522-018-0057-2 PMID
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Lukas Wichmann, Kirsty Sophia Vowinkel, Alexander Perniss, Ivan Manzini, Mike Althaus:
Incorporation of the -subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in Xenopus laevis.
doi:10.1074/jbc.RA118.002543 PMID
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Eoghan McGrath, Susan Logue, Katarzyna Mnich, Shane Deegan, Richard Jäger, Adrienne Gorman, Afshin Samali:
The Unfolded Protein Response in Breast Cancer.
PDF Download (CC BY 4.0) doi:10.3390/cancers10100344 urn:nbn:de:hbz:1044-opus-40650 PMID
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Ahmad M. Al‑Dali, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Utilizing ethacrynic acid and ciclopirox olamine in liver cancer.
doi:10.3892/ol.2018.9472 PMID
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Ina Knerr, Laurie Bernstein, Ellen Crushell, Siobhan O’Sullivan, Jörn Oliver Sass:
Amino Acids and Inherited Amino Acid-Related Disorders.
PDF Download (CC BY 4.0) doi:10.1155/2018/5629454 urn:nbn:de:hbz:1044-opus-40610 PMID
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Jörn Oliver Sass, Malkanthi Fernando, Sidney Behringer:
Mimicking Ketonuria in the Ketogenesis Defect 3-Hydroxy-3-Methylglutaryl-Coenzyme A Lyase Deficiency: An Artefact in the Analysis of Urinary Organic Acids.
PDF Download (CC BY 4.0) doi:10.1177/2326409818797361 urn:nbn:de:hbz:1044-opus-40285
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Susan E. Logue, Eoghan P. McGrath, Patricia Cleary, Stephanie Greene, Katarzyna Mnich, Aitor Almanza, Eric Chevet, Róisín M. Dwyer, Anup Oommen, Patrick Legembre, Florence Godey, Emma C. Madden, Brian Leuzzi, Joanna Obacz, Qingping Zeng, John B. Patterson, Richard Jäger, Adrienne M. Gorman, Afshin Samali:
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy.
PDF Download (CC BY 4.0) doi:10.1038/s41467-018-05763-8 PMID urn:nbn:de:hbz:1044-opus-39907
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Ebru Canda, Havva Yazici, E. R. Esra, Sema Kalkan Ucar, Corinne Gemperle-Britschgi, Sara Habif, Huseyin Onay, Jörn Oliver Sass, Mahmut Coker:
Tekrarlayan ketoasidoz atakları: Keton metabolizma bozuklukluğu olabilir mi?.
doi:10.5222/buchd.2018.115
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Jessica I. Hoell, Sebastian Ginzel, Michaela Kuhlen, Andreas Klötgen, Michael Gombert, Ute Fischer, Daniel Schäfer, Martin Stanulla, Martin Schrappe, Udo zur Stadt, Peter Bader, Florian Babor, Friedhelm Schuster, Brigitte Strahm, Julia Alten, Anja Moericke, Gabriele Escherich, Arend von Stackelberg, Ralf Thiele, Alice C. McHardy, Christina Peters, Cornelia Eckert, Arndt Borkhardt, Roland Meisel:
Whole-Exome-Sequencing identifiziert hohe Plastizität, Selektionsdruck und „druggable targets“ in Leukämiezellen pädiatrischer ALL Rezidive nach allogener Stammzelltransplantation.
URL
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Jörn Oliver Sass, Toshiyuki Fukao, Grant A. Mitchell:
Inborn Errors of Ketone Body Metabolism and Transport: An Update for the Clinic and for Clinical Laboratories.
PDF Download (CC BY 4.0) doi:10.1177/2326409818771101 urn:nbn:de:hbz:1044-opus-36412
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A. Korwitz-Reichelt, M. Walter, J. O. Sass:
Human D-glycerate kinase is a mitochondrial protein.
URL
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L. Klaas, J. O. Sass:
Deciphering novel functions of aminoacylases.
URL
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A. Korwitz-Reichelt, D. Tsortouktzidis, K. Grundke, J. O. Sass:
Characterization of acylpeptide hydrolase sequence variants -potential implications for valproic acid efficacy and Alzheimer’s disease.
URL
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Jörn Oliver Sass, Barbara Plecko-Startinig:
Sulfite Oxidase Deficiency/Molybdenum Cofactor Deficiency and Epilepsy.
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Jörn Oliver Sass, Sema Kalkan Uçar, Clara D.M. van Karnebeek:
From rodent heart to inborn errors of human metabolism.
doi:10.1016/j.ymgme.2018.02.001 PMID
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Simon Julius Mayr, Jörn Oliver Sass, Julia Vry, Janbernd Kirschner, Irina Mader, Jan-Bernd Hövener, Jochen Reiss, José Angel Santamaria-Araujo, Günter Schwarz, Sarah Catharina Grünert:
A mild case of molybdenum cofactor deficiency defines an alternative route of MOCS1 protein maturation.
doi:10.1007/s10545-018-0138-7 PMID
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Karl N. Kirschner, Wolfgang Heiden, Dirk Reith:
Small Alcohols Revisited: CCSD(T) Relative Potential Energies for the Minima, First- and Second-Order Saddle Points, and Torsion-Coupled Surfaces.
PDF Download doi:10.1021/acsomega.7b01367 urn:nbn:de:hbz:1044-opus-34995 PMID
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2017
Anna Zakrzewicz, Katrin Richter, Alisa Agne, Sigrid Wilker, Kathrin Siebers, Bijan Fink, Gabriela Krasteva-Christ, Mike Althaus, Winfried Padberg, Arik J. Hone, J. Michael McIntosh, Veronika Grau:
Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1 beta via Different Combinations of Nicotinic Acetylcholine Receptor Subunits alpha 7, alpha 9 and alpha 10.
doi:10.3389/fncel.2017.00189 PMID
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Alexander Perniss, Kathrin Preiss, Marcel Nier, Mike Althaus:
Hydrogen sulfide stimulates CFTR in Xenopus oocytes by activation of the cAMP/PKA signalling axis.
doi:10.1038/s41598-017-03742-5 PMID
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Maryam Keshavarz, Heike Schwarz, Petra Hartmann, Silke Wiegand, Melanie Skill, Mike Althaus, Wolfgang Kummer, Gabriela Krasteva-Christ:
Caveolin-1: Functional Insights into Its Role in Muscarine- and Serotonin-Induced Smooth Muscle Constriction in Murine Airways.
doi:10.3389/fphys.2017.00295 PMID
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Jessica Lohrke, Anna-Lena Frisk, Thomas Frenzel, Laura Schöckel, Martin Rosenbruch, Gregor Jost, Diana Constanze Lenhard, Martin A. Sieber, Volker Nischwitz, Astrid Küppers, Hubertus Pietsch:
Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents.
doi:10.1097/RLI.0000000000000344 PMID
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Gonca Kılıç-Yıldırım, Sultan Durmuş-Aydoğdu, Serdar Ceylaner, Jörn Oliver Sass:
Beta-ketothiolase deficiency: An unusual cause of recurrent ketoacidosis.
doi:10.24953/turkjped.2017.04.016 PMID
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KFM Opuni, S Solomon, F Metzen, D Frommholz, C Koy, C Röwer, MO Glocker, H Illges, PC Anderson:
In silico Epitope Mapping of Glucose-6-Phosphate Isomerase: A Rheumatoid Arthritis Autoantigen.
PDF Download (CC BY 3.0) doi:10.4172/jpb.1000425 urn:nbn:de:hbz:1044-opus-36800
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Arjan Pol, G. Herma Renkema, Albert Tangerman, Edwin G. Winkel, Udo F. Engelke, Arjan P. M. de Brouwer, Kent C. Lloyd, Renee S. Araiza, Lambert van den Heuvel, Heymut Omran, Heike Olbrich, Marijn Oude Elberink, Christian Gilissen, Richard J. Rodenburg, Jörn Oliver Sass, K. Otfried Schwab, Hendrik Schäfer, Hanka Venselaar, J. Silvia Sequeira, Huub J. M. Op den Camp, Ron A. Wevers:
Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis.
doi:10.1038/s41588-017-0006-7 PMID URL
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Glenn M. G. Theunissen, Burkhard Rolf, Andrew Gibb, Richard Jäger:
DNA profiling of sperm cells by using micromanipulation and whole genome amplification.
doi:10.1016/j.fsigss.2017.09.183
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Yelena Yefremova, F. Teresa I. Melder, Bright D. Danquah, Kwabena F. M. Opuni, Cornelia Koy, Alexandra Ehrens, David Frommholz, Harald Illges, Knut Koelbel, Frank Sobott, Michael O. Glocker:
Apparent activation energies of protein–protein complex dissociation in the gas–phase determined by electrospray mass spectrometry.
doi:10.1007/s00216-017-0603-4 PMID
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Stephanie Oerum, Martine Roovers, Michael Leichsenring, Cécile Acquaviva-Bourdain, Frauke Beermann, Corinne Gemperle-Britschgi, Alain Fouilhoux, Anne Korwitz-Reichelt, Henry J. Bailey, Louis Droogmans, Udo Oppermann, Jörn Oliver Sass, Wyatt W. Yue:
Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.
doi:10.1016/j.bbadis.2017.09.002 PMID
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Jan-Niclas Schwade, Matthias Endmann, Thomas Hofmann, Stephan Rust, Jörn Oliver Sass, Frank Rutsch:
When one disease is not enough: Succinyl-CoA: 3-oxoacid coenzyme A transferase (SCOT) deficiency due to a novel mutation in OXCT1 in an infant with known phenylketonuria.
doi:10.1515/jpem-2017-0177 PMID
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Sarah Catharina Grünert, Robert Niklas Schmitt, Sonja Marina Schlatter, Corinne Gemperle-Britschgi, Mehmet Cihan Balcı, Volker Berg, Mahmut Çoker, Anibh M. Das, Mübeccel Demirkol, Terry G. J. Derks, Gülden Gökçay, Sema Kalkan Uçar, Vassiliki Konstantopoulou, G. Christoph Korenke, Amelie Sophia Lotz-Havla, Andrea Schlune, Christian Staufner, Christel Tran, Gepke Visser, Karl Otfried Schwab, Toshiyuki Fukao, Jörn Oliver Sass:
Clinical presentation and outcome in a series of 32 patients with 2-methylacetoacetyl-coenzyme A thiolase (MAT) deficiency.
doi:10.1016/j.ymgme.2017.06.012 PMID
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Sarah Catharina Grünert, Sonja Marina Schlatter, Robert Niklas Schmitt, Corinne Gemperle-Britschgi, Lenka Mrázová, Mehmet Cihan Balcı, Felix Bischof, Mahmut Çoker, Anibh M. Das, Mübeccel Demirkol, Maaike de Vries, Gülden Gökçay, Johannes Häberle, Sema Kalkan Uçar, Amelie Sophia Lotz-Havla, Thomas Lücke, Dominique Roland, Frank Rutsch, René Santer, Andrea Schlune, Christian Staufner, Karl Otfried Schwab, Grant A. Mitchell, Jörn Oliver Sass:
3-Hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: Clinical presentation and outcome in a series of 37 patients.
doi:10.1016/j.ymgme.2017.05.014 PMID
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David Stephan, Hans Weiher, Ingo G. H. Schmidt-Wolf:
CIK Cells and HDAC Inhibitors in Multiple Myeloma.
PDF Download (CC BY 4.0) doi:10.3390/ijms18050945 PMID urn:nbn:de:hbz:1044-opus-30480
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Michael A. Swanson, Stephanie M. Garcia, Elaine Spector, Kathryn Kronquist, Geralyn Creadon-Swindell, Melanie Walter, Ernst Christensen, Johan L.K. van Hove, Jörn Oliver Sass:
d-Glyceric aciduria does not cause nonketotic hyperglycinemia: A historic co-occurrence.
doi:10.1016/j.ymgme.2017.04.009 PMID
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Calogero S. Messina, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Targeting Prostate Cancer with a Combination of WNT Inhibitors and a Bi-functional Peptide.
doi:10.21873/anticanres.11348 PMID
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Attia Kalim, Patricia Fitzsimons, Claudia Till, Malkanthi Fernando, Philip Mayne, Jörn Oliver Sass, Ellen Crushell:
Further evidence that d-glycerate kinase (GK) deficiency is a benign disorder.
doi:10.1016/j.braindev.2017.01.005 PMID
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Karl N. Kirschner, Wolfgang Heiden, Dirk Reith:
Relative electronic and free energies of octane's unique conformations.
doi:10.1080/00268976.2016.1262076
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Chidimma A. Nwangwu, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Increase of CIK cell efficacy by upregulating cell surface MICA and inhibition of NKG2D ligand shedding in multiple myeloma.
doi:10.1002/hon.2326 PMID
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Florian Grahammer, Suresh K. Ramakrishnan, Markus M. Rinschen, Alexey A. Larionov, Maryam Syed, Hazim Khatib, Malte Roerden, Jörn Oliver Sass, Martin Helmstaedter, Dorothea Osenberg, Lucas Kuhne, Oliver Kretz, Nicola Wanner, Francois Jouret, Thomas Benzing, Ferruh Artunc, Tobias B. Huber, Franziska Theilig:
mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells.
doi:10.1681/ASN.2015111224 PMID
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2016
Oskar Schnappauf, Sven Beyes, Annika Dertmann, Vivien Freihen, Patrick Frey, Sabine Jägle, Katja Rose, Tom Michoel, Rudolf Grosschedl, Andreas Hecht:
Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing.
doi:10.1016/j.bbagrm.2016.08.002 PMID
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Nicole C. Krause, Hanna S. Kutsche, Fabrizio Santangelo, Eric R. DeLeon, Nikolaus P. Dittrich, Kenneth R. Olson, Mike Althaus:
Hydrogen sulfide contributes to hypoxic inhibition of airway transepithelial sodium absorption.
doi:10.1152/ajpregu.00177.2016 PMID
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K. Richter, V. Mathes, M. Fronius, M. Althaus, A. Hecker, G. Krasteva-Christ, W. Padberg, A. J. Hone, J. M. McIntosh, A. Zakrzewicz, V. Grau:
Phosphocholine - an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors.
doi:10.1038/srep28660 PMID
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Ervice Pouokam, Mike Althaus:
Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide.
doi:10.1155/2016/4723416 PMID
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Georg Staubli, Matthias Baumgartner, Jörn Oliver Sass, Martin Hersberger:
Laughing Gas in a Pediatric Emergency Department-Fun for All Participants: Vitamin B12 Status Among Medical Staff Working With Nitrous Oxide.
doi:10.1097/PEC.0000000000000582 PMID
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Gregor Jost, Diana Constanze Lenhard, Martin Andrew Sieber, Jessica Lohrke, Thomas Frenzel, Hubertus Pietsch:
Signal Increase on Unenhanced T1-Weighted Images in the Rat Brain After Repeated, Extended Doses of Gadolinium-Based Contrast Agents: Comparison of Linear and Macrocyclic Agents.
doi:10.1097/RLI.0000000000000242 PMID
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Jan Endrikat, Martin A. Sieber, Jacob Agris, Hubertus Pietsch:
Comments on the article "Tissue gadolinium deposition in hepatorenally impaired rats exposed to Gd-EOB-DTPA: evaluation with inductively coupled plasma mass spectrometry (ICP-MS)" by Tomohiro Sato, Tsutomu Tamada, Shigeru Watanabe et al. DOI 10.1007/s11547-014-0492-y.
doi:10.1007/s11547-015-0591-4 PMID
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Hiroki Otsuka, Hideo Sasai, Mina Nakama, Yuka Aoyama, Elsayed Abdelkreem, Hidenori Ohnishi, Vassiliki Konstantopoulou, Jörn Oliver Sass, Toshiyuki Fukao:
Exon 10 skipping in ACAT1 caused by a novel c.949G>A mutation located at an exonic splice enhancer site.
doi:10.3892/mmr.2016.5819 PMID
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Jörn Oliver Sass, Corinne Gemperle-Britschgi, Maja Tarailo-Graovac, Nisha Patel, Melanie Walter, Albena Jordanova, Majid Alfadhel, Ivo Barić, Mahmut Coker, Aynur Damli-Huber, Eissa Ali Faqeih, Nuria García Segarra, Michael T. Geraghty, Bjørn Magne Jåtun, Sema Kalkan Ucar, Merten Kriewitz, Markus Rauchenzauner, Karmen Bilić, Ivailo Tournev, Claudia Till, Bryan Sayson, Daniel Beumer, Cynthia Xin Ye, Lin-Hua Zhang, Hilary Vallance, Fowzan S. Alkuraya, Clara D.M. van Karnebeek:
Unravelling 5-oxoprolinuria (pyroglutamic aciduria) due to bi-allelic OPLAHmutations: 20 new mutations in 14 families.
doi:10.1016/j.ymgme.2016.07.008 PMID
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Laura Esser, Hans Weiher, Ingo Schmidt-Wolf:
Increased Efficacy of Brentuximab Vedotin (SGN-35) in Combination with Cytokine-Induced Killer Cells in Lymphoma.
PDF Download (CC BY 4.0) doi:10.3390/ijms17071056 PMID urn:nbn:de:hbz:1044-opus-25300
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Maria Joosten, Sebastian Ginzel, Christian Blex, Dmitri Schmidt, Michael Gombert, Cai Chen, René Martin Linka, Olivia Gräbner, Anika Hain, Burkhard Hirsch, Anke Sommerfeld, Anke Seegebarth, Uschi Gruber, Corinna Maneck, Langhui Zhang, Katharina Stenin, Henrik Dieks, Michael Sefkow, Carsten Münk, Claudia D. Baldus, Ralf Thiele, Arndt Borkhardt, Michael Hummel, Hubert Köster, Ute Fischer, Mathias Dreger, Volkhard Seitz:
A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma.
doi:10.1016/j.molonc.2016.06.001 PMID
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Roman Rombo, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Effect of chaetocin on renal cell carcinoma cells and cytokine-induced killer cells.
PDF Download (CC BY 4.0) doi:10.3205/000231 PMID urn:nbn:de:hbz:1044-opus-24148
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Hans Weiher, Haymo Pircher, Pidder Jansen-Dürr, Silke Hegenbarth, Percy Knolle, Silke Grunau, Miia Vapola, J. Kalervo Hiltunen, Ralf M. Zwacka, Elmon Schmelzer, Kerstin Reumann, Hans Will:
A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells.
PDF Download (CC BY 4.0) doi:10.1186/s13104-016-1939-0 PMID urn:nbn:de:hbz:1044-opus-23274
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Nasser Dhayat, Alexandre Simonin, Manuel Anderegg, Ganesh Pathare, Benjamin P. Lüscher, Christine Deisl, Giuseppe Albano, David Mordasini, Matthias A. Hediger, Daniel V. Surbek, Bruno Vogt, Jörn Oliver Sass, Barbara Kloeckener-Gruissem, Daniel G. Fuster:
Mutation in the Monocarboxylate Transporter 12 Gene Affects Guanidinoacetate Excretion but Does Not Cause Glucosuria.
doi:10.1681/ASN.2015040411 PMID
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Jörn Oliver Sass, Jathana Vaithilingam, Corinne Gemperle-Britschgi, Cathérine C. S. Delnooz, Leo A. J. Kluijtmans, Bart P. C. van de Warrenburg, Ron A. Wevers:
Expanding the phenotype in aminoacylase 1 (ACY1) deficiency: characterization of the molecular defect in a 63-year-old woman with generalized dystonia.
doi:10.1007/s11011-015-9778-6 PMID
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Shanti Balasubramaniam, Barry Lewis, Lawrence Greed, David Meili, Annegret Flier, Raina Yamamoto, Karmen Bilić, Claudia Till, Jörn Oliver Sass:
Heterozygous Monocarboxylate Transporter 1 (MCT1, SLC16A1) Deficiency as a Cause of Recurrent Ketoacidosis.
doi:10.1007/8904_2015_519 PMID
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2015
Oskar Schnappauf:
Mechanisms of enhancer regulation.
doi:10.6094/UNIFR/10194 URL
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Alexander Perniss, Annemarie Wolf, Lukas Wichmann, Matthias Schoenberger, Mike Althaus:
Evans Blue is not a suitable inhibitor of the epithelial sodium channel δ-subunit.
doi:10.1016/j.bbrc.2015.09.052 PMID
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Alisa M. Agne, Jan-Peter Baldin, Audra R. Benjamin, Maria C. Orogo-Wenn, Lukas Wichmann, Kenneth R. Olson, Dafydd V. Walters, Mike Althaus:
Hydrogen sulfide decreases β-adrenergic agonist-stimulated lung liquid clearance by inhibiting ENaC-mediated transepithelial sodium absorption.
doi:10.1152/ajpregu.00489.2014 PMID
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Victoria Elsner, Volker Wulf, Michaela Wirtz, Oliver J. Schmitz:
Reproducibility of retention time and peak area in comprehensive two-dimensional liquid chromatography.
doi:10.1007/s00216-014-8090-3 PMID
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Vasily D. Antonenkov, Antti Isomursu, Daniela Mennerich, Miia H. Vapola, Hans Weiher, Thomas Kietzmann, J. Kalervo Hiltunen:
The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential.
doi:10.1074/jbc.M114.608083 PMID
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Thomas Frenzel, Rüdiger Lawaczeck, Matthias Taupitz, Gregor Jost, Jessica Lohrke, Martin A. Sieber, Hubertus Pietsch:
Contrast Media for X-ray and Magnetic Resonance Imaging: Development, Current Status and Future Perspectives.
doi:10.1097/RLI.0000000000000193 PMID
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Behzad Yeganeh, Richard Jäger, Adrienne M. Gorman, Afshin Samali, Saeid Ghavami:
Induction of Autophagy: Role of Endoplasmic Reticulum Stress and Unfolded Protein Response.
doi:10.1016/B978-0-12-801043-3.00005-4
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Karl Linke, Harald Illges:
Detection of sCD21 in Human Blood Using ELISA is Influenced by Ethylenediaminetetraacetic Acid (EDTA) Containing Blood Collection Tubes.
doi:10.7754/Clin.Lab.2015.150333 PMID
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Manuel Kehl, Markus Enzweiler, Bjoern Froehlich, Uwe Franke, Wolfgang Heiden:
Vision-Based Road Sign Detection.
doi:10.1109/ITSC.2015.89
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Alberto Martin-Lorenzo, Julia Hauer, Carolina Vicente-Duenas, Franziska Auer, Ines Gonzalez-Herrero, Idoia Garcia-Ramirez, Sebastian Ginzel, Ralf Thiele, Stefan N. Constantinescu, Christoph Bartenhagen, Martin Dugas, Michael Gombert, Daniel Schafer, Oscar Blanco, Andrea Mayado, Alberto Orfao, Diego Alonso-Lopez, Javier de Las Rivas, Cesar Cobaleda, Maria Begona Garcia-Cenador, Francisco Javier Garcia-Criado, Isidro Sanchez-Garcia, Arndt Borkhardt:
Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.
doi:10.1158/2159-8290.CD-15-0892 PMID
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Schafiq Nabhani, Sebastian Ginzel, Hagit Miskin, Shoshana Revel-Vilk, Dan Harlev, Bernhard Fleckenstein, Andrea Hönscheid, Prasad T. Oommen, Michaela Kuhlen, Ralf Thiele, Hans-Jürgen Laws, Arndt Borkhardt, Polina Stepensky, Ute Fischer:
Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease.
doi:10.3324/haematol.2014.114967 PMID
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Ute Fischer, Michael Forster, Anna Rinaldi, Thomas Risch, Stéphanie Sungalee, Hans-Jörg Warnatz, Beat Bornhauser, Michael Gombert, Christina Kratsch, Adrian M. Stütz, Marc Sultan, Joelle Tchinda, Catherine L. Worth, Vyacheslav Amstislavskiy, Nandini Badarinarayan, André Baruchel, Thies Bartram, Giuseppe Basso, Cengiz Canpolat, Gunnar Cario, Hélène Cavé, Dardane Dakaj, Mauro Delorenzi, Maria Pamela Dobay, Cornelia Eckert, Eva Ellinghaus, Sabrina Eugster, Viktoras Frismantas, Sebastian Ginzel, Oskar A. Haas, Olaf Heidenreich, Georg Hemmrich-Stanisak, Kebria Hezaveh, Jessica I. Höll, Sabine Hornhardt, Peter Husemann, Priyadarshini Kachroo, Christian P. Kratz, Geertruy Te Kronnie, Blerim Marovca, Felix Niggli, Alice C. McHardy, Anthony V. Moorman, Renate Panzer-Grümayer, Britt S. Petersen, Benjamin Raeder, Meryem Ralser, Philip Rosenstiel, Daniel Schäfer, Martin Schrappe, Stefan Schreiber, Moritz Schütte, Björn Stade, Ralf Thiele, Nicolas von der Weid, Ajay Vora, Marketa Zaliova, Langhui Zhang, Thomas Zichner, Martin Zimmermann, Hans Lehrach, Arndt Borkhardt, Jean-Pierre Bourquin, Andre Franke, Jan O. Korbel, Martin Stanulla, Marie-Laure Yaspo:
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
doi:10.1038/ng.3362 PMID URL
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Cai Chen, Christoph Bartenhagen, Michael Gombert, Vera Okpanyi, Vera Binder, Silja Röttgers, Jutta Bradtke, Andrea Teigler-Schlegel, Jochen Harbott, Sebastian Ginzel, Ralf Thiele, Peter Husemann, Pina F.I. Krell, Arndt Borkhardt, Martin Dugas, Jianda Hu, Ute Fischer:
Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.
doi:10.1016/j.leukres.2015.06.005 PMID
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Jacob Hagen, Heleen te Brinke, Ronald J A Wanders, Alida C. Knegt, Esmee Oussoren, A Jeannette M Hoogeboom, George J G Ruijter, Daniel Becker, Karl Otfried Schwab, Ingo Franke, Marinus Duran, Hans R. Waterham, Jörn Oliver Sass, Sander M. Houten:
Genetic basis of alpha-aminoadipic and alpha-ketoadipic aciduria.
doi:10.1007/s10545-015-9841-9 PMID
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Stefanie Löllgen, Hans Weiher:
The role of the Mpv17 protein mutations of which cause mitochondrial DNA depletion syndrome (MDDS): lessons from homologs in different species.
doi:10.1515/hsz-2014-0198 PMID
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Donna Kennedy, Afshin Samali, Richard Jäger:
Methods for Studying ER Stress and UPR Markers in Human Cells.
doi:10.1007/978-1-4939-2522-3_1 PMID
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2014
Matthias Schoenberger, Mike Althaus, Martin Fronius, Wolfgang Clauss, Dirk Trauner:
Controlling epithelial sodium channels with light using photoswitchable amilorides.
doi:10.1038/nchem.2004 PMID
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Alexandra Erb, Mike Althaus:
Actions of Hydrogen Sulfide on Sodium Transport Processes across Native Distal Lung Epithelia (Xenopus laevis).
doi:10.1371/journal.pone.0100971 PMID
BibTeX | RIS
Klaus Deckmann, Katharina Filipski, Gabriela Krasteva-Christ, Martin Fronius, Mike Althaus, Amir Rafiq, Tamara Papadakis, Liane Renno, Innokentij Jurastow, Lars Wessels, Miriam Wolff, Burkhard Schuetz, Eberhard Weihe, Vladimir Chubanov, Thomas Gudermann, Jochen Klein, Thomas Bschleipfer, Wolfgang Kummer:
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes.
doi:10.1073/pnas.1402436111 PMID
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Anna Bell, Mike Althaus, Martin Diener:
Communication between mast cells and rat submucosal neurons.
doi:10.1007/s00424-014-1609-9 PMID
BibTeX | RIS
Schafiq Nabhani, Sebastian Ginzel, Hagit Miskin, Shoshana Revel-Vilk, Dan Harlev, Bernhard Fleckenstein, Andrea Höhnscheid, Prasad T. Oommen, Michaela Kuhlen, Ralf Thiele, Hans-Jürgen Laws, Arndt Borkhardt, Polina Stepensky, Ute Fischer:
Dysregulation of IL12 Signaling As a Novel Cause of an Autoimmune Lymphoproliferative like Syndrome.
doi:10.1182/blood.v124.21.1420.1420
BibTeX | RIS
Marta Torrente, Adriano Guetg, Jörn Oliver Sass, Lisa Arps, Lisa Ruckstuhl, Simone M. R. Camargo, François Verrey:
Amino acids regulate transgene expression in MDCK cells.
doi:10.1371/journal.pone.0096823 PMID
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Miriam S. Reuter, Jörn Oliver Sass, Thomas Leis, Julia Köhler, Johannes A. Mayr, René G. Feichtinger, Manfred Rauh, Ina Schanze, Luzy Bähr, Regina Trollmann, Steffen Uebe, Arif B. Ekici, André Reis:
HIBCH deficiency in a patient with phenotypic characteristics of mitochondrial disorders.
doi:10.1002/ajmg.a.36766 PMID
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Alexander Laemmle, Christian Balmer, Carsten Doell, Jörn Oliver Sass, Johannes Häberle, Matthias R. Baumgartner:
Propionic acidemia in a previously healthy adolescent with acute onset of dilated cardiomyopathy.
doi:10.1007/s00431-014-2359-6 PMID
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Zsofia Kovacs, Beat Werner, Anahita Rassi, Jörn Oliver Sass, Ernst Martin-Fiori, Michele Bernasconi:
Prolonged survival upon ultrasound-enhanced doxorubicin delivery in two syngenic glioblastoma mouse models.
doi:10.1016/j.jconrel.2014.05.033 PMID
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Toshiyuki Fukao, Grant Mitchell, Jörn Oliver Sass, Tomohiro Hori, Kenji Orii, Yuka Aoyama:
Ketone body metabolism and its defects.
doi:10.1007/s10545-014-9704-9 PMID
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Matthias R. Baumgartner, Friederike Hörster, Carlo Dionisi-Vici, Goknur Haliloglu, Daniela Karall, Kimberly A. Chapman, Martina Huemer, Michel Hochuli, Murielle Assoun, Diana Ballhausen, Alberto Burlina, Brian Fowler, Sarah C. Grünert, Stephanie Grünewald, Tomas Honzik, Begoña Merinero, Celia Pérez-Cerdá, Sabine Scholl-Bürgi, Flemming Skovby, Frits Wijburg, Anita MacDonald, Diego Martinelli, Jörn Oliver Sass, Vassili Valayannopoulos, Anupam Chakrapani:
Proposed guidelines for the diagnosis and management of methylmalonic and propionic acidemia.
doi:10.1186/s13023-014-0130-8 PMID
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M. A. Sieber, H. Pietsch, H. Michaely:
Nephrogene Systemische Fibrose (NSF).
BibTeX | RIS
M. A. Sieber, J. K. E. Hegel:
Azelaic Acid: Properties and Mode of Action.
doi:10.1159/000354888 PMID
BibTeX | RIS
Narendiran Rajasekaran, Harald Illges:
Matrix Metalloproteinase MMP-9 Promotes K/BxN Serum Induced Arthritis in Mice.
PDF Download (CC BY 3.0) doi:10.4236/ojra.2014.41003 urn:nbn:de:hbz:1044-opus-22932
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G. Heisenberg, Y. A. Rezaei, T. Rothdeutsch, W. Heiden:
Arm prosthesis simulation on a virtual reality L-shaped workbench display system using a brain computer interface.
BibTeX | RIS
Wolfgang Heiden:
Visualization Issues of Biological and Chemical Models.
BibTeX | RIS
Eric Fassbender, Wolfgang Heiden:
Atmosphaeres – 360° Video Environments for Stress and Pain Management.
doi:10.1007/978-3-319-11623-5_5
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Afshin Samali, Richard Jäger:
Mechanisms of Resistance to Cell Death Pathways in Cancer Cells.
doi:10.1016/B978-0-12-386456-7.01907-9
BibTeX | RIS
Donna Kennedy, Richard Jäger, Dick D. Mosser, Afshin Samali:
Regulation of apoptosis by heat shock proteins.
doi:10.1002/iub.1274 PMID
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Patrick F. Connolly, Richard Jäger, Howard O. Fearnhead:
New roles for old enzymes: killer caspases as the engine of cell behavior changes.
PDF Download (CC BY 3.0) doi:10.3389/fphys.2014.00149 PMID urn:nbn:de:hbz:1044-opus-13374
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J. I. Hoell, M. Gombert, S. Ginzel, S. Loth, P. Landgraf, V. Käfer, M. Streiter, A. Prokop, M. Weiss, R. Thiele, A. Borkhardt:
Constitutional Mismatch Repair-deficiency and Whole-exome Sequencing as the Means of the Rapid Detection of the Causative MSH6 Defect.
doi:10.1055/s-0034-1389905 PMID
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Yashar Abbasalizadeh Rezaei, Gernot Heisenberg, Wolfgang Heiden:
User Interface Design for Disabled People Under the Influence of Time, Efficiency and Costs.
doi:10.1007/978-3-319-07854-0_35
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2013
Matthias Schoenberger, Mike Althaus:
Novel small molecule epithelial sodium channel inhibitors as potential therapeutics in cystic fibrosis - a patent evaluation.
doi:10.1517/13543776.2013.829454 PMID
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Mike Althaus, Wolfgang G. Clauss:
Gasotransmitters: novel regulators of ion channels and transporters.
doi:10.3389/fphys.2013.00027 PMID
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Mike Althaus:
ENaC inhibitors and airway re-hydration in cystic fibrosis: state of the art.
doi:10.2174/18744672112059990025 PMID
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Saskia B. Wortmann, Leo A. J. Kluijtmans, Richard J. Rodenburg, Jörn Oliver Sass, Jessica Nouws, Edwin P. van Kaauwen, Tjitske Kleefstra, Lisbeth Tranebjaerg, Maaike C. de Vries, Pirjo Isohanni, Katharina Walter, Fowzan S. Alkuraya, Izelle Smuts, Carolus J. Reinecke, Francois H. van der Westhuizen, David Thorburn, Jan A. M. Smeitink, Eva Morava, Ron A. Wevers:
3-Methylglutaconic aciduria--lessons from 50 genes and 977 patients.
doi:10.1007/s10545-012-9579-6 PMID
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Naeem Shafqat, Kate L. Kavanagh, Jörn Oliver Sass, Ernst Christensen, Toshiyuki Fukao, Wen Hwa Lee, Udo Oppermann, Wyatt W. Yue:
A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.
doi:10.1007/s10545-013-9589-z PMID
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Sander M. Houten, Heleen te Brinke, Simone Denis, Jos Pn Ruiter, Alida C. Knegt, Johannis Bc de Klerk, Persephone Augoustides-Savvopoulou, Johannes Häberle, Matthias R. Baumgartner, Turgay Coşkun, Johannes Zschocke, Jörn Oliver Sass, Bwee Tien Poll-The, Ronald Ja Wanders, Marinus Duran:
Genetic basis of hyperlysinemia.
doi:10.1186/1750-1172-8-57 PMID
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Sarah C. Grünert, Pablo Villavicencio-Lorini, Bendicht Wermuth, Willy Lehnert, Jörn Oliver Sass, K. Otfried Schwab:
Ornithine transcarbamylase deficiency combined with type 1 diabetes mellitus - a challenge in clinical and dietary management.
doi:10.1186/2251-6581-12-37 PMID
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Sarah C. Grünert, Stephanie Müllerleile, Linda de Silva, Michael Barth, Melanie Walter, Kerstin Walter, Thomas Meissner, Martin Lindner, Regina Ensenauer, René Santer, Olaf A. Bodamer, Matthias R. Baumgartner, Michaela Brunner-Krainz, Daniela Karall, Claudia Haase, Ina Knerr, Thorsten Marquardt, Julia B. Hennermann, Robert Steinfeld, Skadi Beblo, Hans-Georg Koch, Vassiliki Konstantopoulou, Sabine Scholl-Bürgi, Agnes van Teeffelen-Heithoff, Terttu Suormala, Wolfgang Sperl, Jan P. Kraus, Andrea Superti-Furga, Karl Otfried Schwab, Jörn Oliver Sass:
Propionic acidemia: clinical course and outcome in 55 pediatric and adolescent patients.
doi:10.1186/1750-1172-8-6 PMID
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Sarah C. Grünert, Corinna M. Brichta, Andreas Krebs, Hans-Willi Clement, Reinhold Rauh, Christian Fleischhaker, Klaus Hennighausen, Jörn Oliver Sass, K. Otfried Schwab:
Diurnal variation of phenylalanine and tyrosine concentrations in adult patients with phenylketonuria: subcutaneous microdialysis is no adequate tool for the determination of amino acid concentrations.
doi:10.1186/1475-2891-12-60 PMID
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Monica Del Rizzo, Alessandro P. Burlina, Jörn Oliver Sass, Frauke Beermann, Chiara Zanco, Chiara Cazzorla, Andrea Bordugo, Laura Giordano, Renzo Manara, Alberto B. Burlina:
Metabolic stroke in a late-onset form of isolated sulfite oxidase deficiency.
doi:10.1016/j.ymgme.2013.01.011 PMID
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Viktor A. Czaika, Jan Siebenbrock, Frank Czekalla, Torsten Zuberbier, Martin A. Sieber:
Reactive oxygen species and the bacteriostatic and bactericidal effects of isoconazole nitrate.
doi:10.1111/myc.12055 PMID
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Lisa Vincenz, Richard Jäger, Michael O'Dwyer, Afshin Samali:
Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma.
doi:10.1158/1535-7163.MCT-12-0782 PMID
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Richard Jäger, Howard O. Fearnhead:
Mitochondrial Regulation of Cell-Death.
doi:10.1007/978-1-4614-9326-6_3
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Christopher Volk:
OCTs, OATs, and OCTNs: structure and function of the polyspecific organic ion transporters of the SLC22 family.
doi:10.1002/wmts.100
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Anjana Singh, Narendiran Rajasekaran, Bettina Hartenstein, Sibylle Szabowski, Mieczyslaw Gajda, Peter Angel, Rolf Bräuer, Harald Illges:
Collagenase-3 (MMP-13) deficiency protects C57BL/6 mice from antibody-induced arthritis.
PDF Download (CC BY 2.0) doi:10.1186/ar4423 PMID urn:nbn:de:hbz:1044-opus-10819
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Anjana Singh, Lin Leng, Juan Fan, Mieczyslaw Gajda, Rolf Bräuer, Günter Fingerle-Rowson, Richard Bucala, Harald Illges:
Macrophage-derived, macrophage migration inhibitory factor (MIF) is necessary to induce disease in the K/BxN serum-induced model of arthritis.
doi:10.1007/s00296-013-2713-4 PMID
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Elisa Nent, David Frommholz, Mieczyslaw Gajda, Rolf Bräuer, Harald Illges:
Histamine 4 receptor plays an important role in auto-antibody-induced arthritis.
doi:10.1093/intimm/dxt008 PMID
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Y. Linka, S. Ginzel, M. Krüger, A. Novosel, M. Gombert, E. Kremmer, J. Harbott, R. Thiele, A. Borkhardt, P. Landgraf:
The impact of TEL-AML1 (ETV6-RUNX1) expression in precursor B cells and implications for leukaemia using three different genome-wide screening methods.
PDF Download (CC BY-NC-SA 3.0) doi:10.1038/bcj.2013.48 PMID urn:nbn:de:hbz:1044-opus-10394
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Cai Chen, Christoph Bartenhagen, Michael Gombert, Vera Okpanyi, Vera Binder, Andrea Teigler-Schlegel, Jutta Bradtke, Silja Roettgers, Jochen Harbott, Sebastian Ginzel, Ralf Thiele, Martin Dugas, Jianda Hu, Arndt Borkhardt, Ute Fischer:
Chromothripsis-Mediated Structural Variations and Clonal Evolution In Recurrent Childhood High Hyperdiploid Acute Lymphoblastic Leukemia.
doi:10.1182/blood.v122.21.233.233
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Cai Chen, Christoph Bartenhagen, Michael Gombert, Vera Okpanyi, Vera Binder, Silja Roettgers, Jutta Bradtke, Andrea Teigler-Schlegel, Jochen Harbott, Sebastian Ginzel, Ralf Thiele, Ute Fischer, Martin Dugas, Jianda Hu, Arndt Borkhardt:
Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.
doi:10.1002/gcc.22054 PMID
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2012
Clara E. Jäkel, Karoline Meschenmoser, Young Kim, Hans Weiher, Ingo G. H. Schmidt-Wolf:
Efficacy of a proapoptotic peptide towards cancer cells.
URL PMID
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Richard Jäger, Howard O. Fearnhead:
"Dead Cells Talking": The Silent Form of Cell Death Is Not so Quiet.
PDF Download (CC BY 3.0) doi:10.1155/2012/453838 PMID urn:nbn:de:hbz:1044-opus-9505
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Anjana Singh, Sebastiaan J. Vastert, Berent J. Prakken, Harald Illges:
Decreased levels of sCD21 and sCD23 in blood of patients with systemic-juvenile arthritis, polyarticular-juvenile arthritis, and pauciarticular-juvenile arthritis.
doi:10.1007/s00296-011-1830-1 PMID
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Michael Raffelsieper, Birgit Mielenz, Susanne Häußler, Helga Sauerwein, Manfred Mielenz, Harald Illges:
A Monoclonal Antibody Against Bovine Adiponectin.
doi:10.1089/hyb.2012.0054 PMID
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Hui Zhi Low, Dorothee Hilbrans, Ingo G. H. Schmidt-Wolf, Harald Illges:
Enhanced CD21 expression and shedding in chronic lymphatic leukemia: a possible pathomechanism in disease progression.
doi:10.1007/s12185-012-1147-1 PMID
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David Frommholz, Harald Illges:
Maximal locomotor depression follows maximal ankle swelling during the progression of arthritis in K/BxN mice.
doi:10.1007/s00296-011-2337-5 PMID
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Vera Okpanyi, Christoph Bartenhagen, Michael Gombert, Sebastian Ginzel, Pina Fanny Ida Krell, Peter Husemann, Cai Chen, Vera Binder, Jutta Bradtke, Andrea Teigler-Schlegel, Silja Roettgers, Jochen Harbott, Martin Stanulla, Cornelia Eckert, Ralf Thiele, Martin Dugas, Arndt Borkhardt, Ute Fischer:
Novel Genomic Structural Variations in Relapsed Childhood ETV6/RUNX1 (TEL/AML1) Acute Lymphoblastic Leukemias Identified by Next Generation Sequencing.
doi:10.1182/blood.V120.21.518.518
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Gernot Heisenberg, Ramesh K. Natarajan, Yashar A. Rezaei, Nicolas Simon, Wolfgang Heiden:
Robust EEG time series transient detection with a momentary frequency estimator for the indication of an emotional change.
BibTeX | RIS
Eric Fassbender, Deborah Richards, Ayse Bilgin, William Forde Thompson, Wolfgang Heiden:
VirSchool: The effect of background music and immersive display systems on memory for facts learned in an educational virtual environment.
doi:10.1016/j.compedu.2011.09.002
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Patrick Krumm, Teresa Giraldez, Diego Alvarez de la Rosa, Wolfgang G. Clauss, Martin Fronius, Mike Althaus:
Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC).
doi:10.1016/j.bmc.2012.05.021 PMID
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Martin Fronius, Wolfgang G. Clauss, Mike Althaus:
Why do we have to move fluid to be able to breathe?.
doi:10.3389/fphys.2012.00146 PMID
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Mike Althaus:
Gasotransmitters: novel regulators of epithelial Na+ transport?.
doi:10.3389/fphys.2012.00083 PMID
BibTeX | RIS
Diana Wesch, Mike Althaus, Pablo Miranda, Ignacio Cruz-Muros, Martin Fronius, Tomas Gonzalez-Hernandez, Wolfgang G. Clauss, Diego Alvarez de la Rosa, Teresa Giraldez:
Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane.
doi:10.1152/ajpcell.00255.2011 PMID
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M. Althaus, K. D. Urness, W. G. Clauss, D. L. Baines, M. Fronius:
The gasotransmitter hydrogen sulphide decreases Na⁺ transport across pulmonary epithelial cells.
doi:10.1111/j.1476-5381.2012.01909.x PMID
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Michel van Weeghel, Heleen te Brinke, Henk van Lenthe, Wim Kulik, Paul E. Minkler, Maria S. K. Stoll, Jörn Oliver Sass, Uwe Janssen, Wilhelm Stoffel, K. Otfried Schwab, Ronald J. A. Wanders, Charles L. Hoppel, Sander M. Houten:
Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsaturated fatty acids.
doi:10.1096/fj.12-206326 PMID
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Carsten Speckmann, Carla Neumann, Stephan Borte, Giancarlo La Marca, Jörn Oliver Sass, Elisabeth Wiech, Paul Fisch, Klaus Schwarz, Bernd Buchholz, Michael Schlesier, Kerstin Felgentreff, Bodo Grimbacher, Ines Santisteban, Pawan Bali, Michael S. Hershfield, Stephan Ehl:
Delayed-onset adenosine deaminase deficiency: strategies for an early diagnosis.
doi:10.1016/j.jaci.2012.04.004 PMID
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Anke Sommer, Jörn Oliver Sass:
Expression of aspartoacylase (ASPA) and Canavan disease.
doi:10.1016/j.gene.2012.06.036 PMID
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Sabine Scholl-Bürgi, Jörn Oliver Sass, Johannes Zschocke, Daniela Karall:
Amino acid metabolism in patients with propionic acidaemia.
doi:10.1007/s10545-010-9245-9 PMID
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Jörn Oliver Sass, Melanie Walter, Julian P. H. Shield, Andrea M. Atherton, Uttam Garg, David Scott, C. Geoffrey Woods, Laurie D. Smith:
3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase.
doi:10.1007/s10545-011-9381-x PMID
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Jörn Oliver Sass:
Inborn errors of ketogenesis and ketone body utilization.
doi:10.1007/s10545-011-9324-6 PMID
BibTeX | RIS
Jörn Oliver Sass:
Disorders of the degradation of branched chain amino acids: what is new in clinics and laboratories?.
doi:10.1007/s10545-011-9420-7 PMID
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Makiko Nakamura, Yamaguchi Yuichiro, Jörn Oliver Sass, Matsumura Tomohiro, Karl Otfried Schwab, Nishino Takeshi, Hosoya Tatsuo, Kimiyoshi Ichida:
Identification of a xanthinuria type I case with mutations of xanthine dehydrogenase in an Afghan child.
doi:10.1016/j.cca.2012.08.011 PMID
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J. P. Kraus, E. Spector, S. Venezia, P. Estes, P. W. Chiang, G. Creadon-Swindell, S. Müllerleile, L. de Silva, M. Barth, M. Walter, K. Walter, T. Meissner, M. Lindner, R. Ensenauer, R. Santer, O. A. Bodamer, M. R. Baumgartner, M. Brunner-Krainz, D. Karall, C. Haase, I. Knerr, T. Marquardt, J. B. Hennermann, R. Steinfeld, S. Beblo, H. G. Koch, V. Konstantopoulou, S. Scholl-Bürgi, A. van Teeffelen-Heithoff, T. Suormala, M. Ugarte, W. Sperl, A. Superti-Furga, K. O. Schwab, S. C. Grünert, J. O. Sass:
Mutation analysis in 54 propionic acidemia patients.
doi:10.1007/s10545-011-9399-0 PMID
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Sarah Catharina Grünert, Karl Otfried Schwab, Martin Pohl, Jörn Oliver Sass, René Santer:
Fanconi-Bickel syndrome: GLUT2 mutations associated with a mild phenotype.
doi:10.1016/j.ymgme.2011.11.200 PMID
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S. C. Grünert, S. Müllerleile, L. de Silva, M. Barth, M. Walter, K. Walter, T. Meissner, M. Lindner, R. Ensenauer, R. Santer, O. A. Bodamer, M. R. Baumgartner, M. Brunner-Krainz, D. Karall, C. Haase, I. Knerr, T. Marquardt, J. B. Hennermann, R. Steinfeld, S. Beblo, H. G. Koch, V. Konstantopoulou, S. Scholl-Bürgi, A. van Teeffelen-Heithoff, T. Suormala, W. Sperl, J. P. Kraus, A. Superti-Furga, K. O. Schwab, J. O. Sass:
Propionic acidemia: neonatal versus selective metabolic screening.
doi:10.1007/s10545-011-9419-0 PMID
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M. Binder, M. Uhl, T. Wiech, F. Kollert, J. Thiel, J. O. Sass, U. A. Walker, H. H. Peter, K. Warnatz:
Cyclophosphamide is a highly effective and safe induction therapy in chronic periaortitis: a long-term follow-up of 35 patients with chronic periaortitis.
doi:10.1136/annrheumdis-2011-200148 PMID
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Abdel Ali Belaidi, Sita Arjune, Jose Angel Santamaria-Araujo, Jörn Oliver Sass, Guenter Schwarz:
Molybdenum cofactor deficiency: a new HPLC method for fast quantification of s-sulfocysteine in urine and serum.
doi:10.1007/8904_2011_89 PMID
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Diana C. Lenhard, Hubertus Pietsch, Martin A. Sieber, Rainer Ernst, Philipp Lengsfeld, Peter Ellinghaus, Gregor Jost:
The osmolality of nonionic, iodinated contrast agents as an important factor for renal safety.
doi:10.1097/RLI.0b013e318258502b PMID
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Tom Verfaillie, Richard Jäger, Afshin Samali, Patrizia Agostinis:
ER Stress Signaling Pathways in Cell Survival and Death.
doi:10.1007/978-94-007-4351-9_3
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Sandra J. M. Healy, Tom Verfaillie, Richard Jäger, Patrizia Agostinis, Afshin Samali:
Biology of the Endoplasmic Reticulum.
doi:10.1007/978-94-007-4351-9_1
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Richard Jäger, Mathieu J. M. Bertrand, Adrienne M. Gorman, Peter Vandenabeele, Afshin Samali:
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.
doi:10.1111/boc.201100055 PMID
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Jens Thiel, Lucas Kimmig, Ulrich Salzer, Magdalena Grudzien, Dirk Lebrecht, Tina Hagena, Ruth Draeger, Nadine Voelxen, Nadine Völxen, Astrid Bergbreiter, Stephanie Jennings, Sylvia Gutenberger, Annette Aichem, Harald Illges, Jonathan P. Hannan, Anne-Kathrin Kienzler, Marta Rizzi, Hermann Eibel, Hans-Hartmut Peter, Klaus Warnatz, Bodo Grimbacher, Jörg-Andres Rump, Michael Schlesier:
Genetic CD21 deficiency is associated with hypogammaglobulinemia.
doi:10.1016/j.jaci.2011.09.027 PMID
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Adrienne M. Gorman, Sandra J.M. Healy, Richard Jäger, Afshin Samali:
Stress management at the ER: Regulators of ER stress-induced apoptosis.
doi:10.1016/j.pharmthera.2012.02.003 PMID
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2011
R. Zwacka, A. Mohr, I. Herr, H. Weiher:
DNA Sequencing.
BibTeX | RIS
H. Weiher, R. Zwacka, I. Herr:
Isolation of DNA and RNA.
BibTeX | RIS
H. Weiher, R. Zwacka, I. Herr:
Hybridization of Nucleic Acids.
BibTeX | RIS
H. Weiher, R. Zwacka, I. Herr:
Chromatography and Electrophoresis of Nucleic Acids.
BibTeX | RIS
A. Mohr, H. Weiher, I. Herr, R. Zwacka:
Polymerase Chain Reaction.
BibTeX | RIS
A. Groth, R. Zwacka, H. Weiher, I. Herr:
Use of Enzymes in the Modification of Nucleic Acids.
BibTeX | RIS
David Frommholz, Martina Krämer, Michael Raffelsieper, Harald Illges:
Kriminaltechnische Methoden zur Aufklärung von Schussdelikten.
doi:10.1007/s12268-011-0028-0
BibTeX | RIS
Katja Denninger, Susanne Rasmussen, Jeppe Madura Larsen, Catrine Ørskov, Steen Seier Poulsen, Poul Sørensen, Jan Pravsgaard Christensen, Harald Illges, Niels Ødum, Tord Labuda:
JNK1, but Not JNK2, Is Required in Two Mechanistically Distinct Models of Inflammatory Arthritis.
doi:10.1016/j.ajpath.2011.06.019 PMID
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Wolfgang Heiden, Monika Turek, Michael J. Schöning:
Analysis of Chemical Sensor Data.
BibTeX | RIS
Wolfgang Heiden, Monika Turek, Michael J. Schöning:
TasteIT - Analyzing Chemical Sensor Data Using Fuzzy Logic.
doi:10.1109/MFCIST.2011.5949520
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Gernot Goebbels, Martin Göbel, André Hinkenjann, Wolfgang Heiden, Marco Winzker, Rainer Herpers, Robert Scholl, Dietmar Reinert:
Institute of Visual Computing at the Bonn-Rhine-Sieg University of Applied Sciences, Germany.
PDF Download (CC BY 4.0) doi:10.5753/jis.2011.574 urn:nbn:de:hbz:1044-opus-8151
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Mike Althaus, Alexandra Pichl, Wolfgang G. Clauss, Werner Seeger, Martin Fronius, Rory E. Morty:
Nitric Oxide Inhibits Highly Selective Sodium Channels and the Na+/K+-ATPase in H441 Cells.
doi:10.1165/2009-0335OC PMID
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Mike Althaus, Wolfgang G. Clauss, Martin Fronius:
Amiloride-sensitive sodium channels and pulmonary edema.
doi:10.1155/2011/830320 PMID
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Lukas Hyzak, Rebecca Moos, Friederike von Rath, Volker Wulf, Michaela Wirtz, David Melchior, Hans-Willi Kling, Michael Kohler, Siegmar Gab, Oliver J. Schmitz:
Quantitative matrix-assisted laser desorption ionization-time-of-flight mass spectrometry analysis of synthetic polymers and peptides.
doi:10.1021/ac2021739 PMID
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Annett Opitz, Michaela Wirtz, David Melchior, Annette Mehling, Hans-Willi Kling, Reinhard H. H. Neubert:
Improved Method for Stratum Corneum Lipid Analysis by Automated Multiple Development HPTLC.
doi:10.1007/s10337-011-1913-x
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Lisenka E. L. M. Vissers, Virginia Fano, Diego Martinelli, Belinda Campos-Xavier, Domenico Barbuti, Tae-Joon Cho, Ahmet Dursun, Ok Hwa Kim, Sun Hee Lee, Giuseppina Timpani, Gen Nishimura, Sheila Unger, Jörn Oliver Sass, Joris A. Veltman, Han G. Brunner, Luisa Bonafé, Carlo Dionisi-Vici, Andrea Superti-Furga:
Whole-exome sequencing detects somatic mutations of IDH1 in metaphyseal chondromatosis with D-2-hydroxyglutaric aciduria (MC-HGA).
doi:10.1002/ajmg.a.34325 PMID
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Anke Sommer, Ernst Christensen, Susanne Schwenger, Ralf Seul, Dorothea Haas, Heike Olbrich, Heymut Omran, Jörn Oliver Sass:
The molecular basis of aminoacylase 1 deficiency.
doi:10.1016/j.bbadis.2011.03.005 PMID
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Jörn Oliver Sass:
Selective screening for inborn errors of metabolism--assessment of metabolites in body fluids.
doi:10.1016/j.clinbiochem.2011.03.017 PMID
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Sarah Catharina Grünert, Brian Fowler, Andrea Superti-Furga, Jörn Oliver Sass, Karl Otfried Schwab:
Hyperpyrexia resulting in encephalopathy in a 14-month-old patient with cblC disease.
doi:10.1016/j.braindev.2010.07.012 PMID
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Toshiyuki Fukao, Jörn Oliver Sass, Petri Kursula, Eva Thimm, Udo Wendel, Can Ficicioglu, Kamel Monastiri, Nathalie Guffon, Ivo Barić, Marie-Therese Zabot, Naomi Kondo:
Clinical and molecular characterization of five patients with succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency.
doi:10.1016/j.bbadis.2011.01.015 PMID
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Gregor Jost, Diana C. Lenhard, Martin A. Sieber, Philipp Lengsfeld, Joachim Hütter, Hubertus Pietsch:
Changes of renal water diffusion coefficient after application of iodinated contrast agents: effect of viscosity.
doi:10.1097/RLI.0b013e31822b1272 PMID
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Gregor Jost, Philipp Lengsfeld, Diana C. Lenhard, Hubertus Pietsch, Joachim Hütter, Martin A. Sieber:
Viscosity of iodinated contrast agents during renal excretion.
doi:10.1016/j.ejrad.2011.02.003 PMID
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Hubertus Pietsch, Marian Raschke, Heidrun Ellinger-Ziegelbauer, Gregor Jost, Jakob Walter, Thomas Frenzel, Diana Lenhard, Joachim Hütter, Martin A. Sieber:
The role of residual gadolinium in the induction of nephrogenic systemic fibrosis-like skin lesions in rats.
doi:10.1097/RLI.0b013e3181efd49a PMID
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Hubertus Pietsch, Gregor Jost, Thomas Frenzel, Marian Raschke, Jakob Walter, Heiko Schirmer, Joachim Hütter, Martin A. Sieber:
Efficacy and safety of lanthanoids as X-ray contrast agents.
doi:10.1016/j.ejrad.2009.10.023 PMID
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Lisa Vincenz, Eva Szegezdi, Richard Jäger, Caitriona Holohan, Timothy O’Brien, Afshin Samali:
Cytokine-Induced β-Cell Stress and Death in Type 1 Diabetes Mellitus.
doi:10.5772/22765
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Wolfgang Heiden:
Augmented Perception for Diagnosis and Orientation Support: Artificial sensors and their application in medicine and navigation.
BibTeX | RIS
2010
Wolfgang Heiden, Matthias Räder, Eric Fassbender:
Interactive Storytelling in Academic Teaching.
doi:10.1007/978-3-642-16638-9_27
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Monika Turek, Wolfgang Heiden, Sharon Guo, Alfred Riesen, Jürgen Schubert, Willi Zander, Peter Krüger, Michael Keusgen, Michael J. Schöning:
Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs.
doi:10.1002/pssa.200983303
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Wolfgang Heiden, Eric Fassbender:
An Edutainment Approach to Academic Teaching Based on Storytelling.
doi:10.5220/0002796301260131
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Diana Wesch, Pablo Miranda, Domingo Afonso-Oramas, Mike Althaus, Javier Castro-Hernandez, Jaime Dominguez, Rory E. Morty, Wolfgang Clauss, Tomas Gonzalez-Hernandez, Diego Alvarez de la Rosa, Teresa Giraldez:
The neuronal-specific SGK1.1 kinase regulates δ-epithelial Na+ channel independently of PY motifs and couples it to phospholipase C signaling.
doi:10.1152/ajpcell.00184.2010 PMID
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Martin Fronius, Roman Bogdan, Mike Althaus, Rory E. Morty, Wolfgang G. Clauss:
Epithelial Na+ channels derived from human lung are activated by shear force.
doi:10.1016/j.resp.2009.11.004 PMID
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Roman Duck, Volker Wulf, Margit Geißler, Hans-Ulrich Baier, Michaela Wirtz, Hans-Willi Kling, Siegmar Gab, Oliver J. Schmitz:
Combination of chemical and electron-impact ionisation with GC x GC-qMS for characterization of fatty alcohol alkoxylate polymers in the low-molecular-weight range up to 700 Da.
doi:10.1007/s00216-009-3434-0 PMID
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Volker Wulf, Nils Wienand, Michaela Wirtz, Hans-Willi Kling, Siegmar Gab, Oliver J. Schmitz:
Analysis of special surfactants by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry.
doi:10.1016/j.chroma.2009.11.093 PMID
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André B. P. van Kuilenburg, Doreen Dobritzsch, Judith Meijer, Rutger Meinsma, Jean-François Benoist, Birgit Assmann, Susanne Schubert, Georg F. Hoffmann, Marinus Duran, Maaike C. de Vries, Gerd Kurlemann, François J. M. Eyskens, Lawrence Greed, Jörn Oliver Sass, K. Otfried Schwab, Adrian C. Sewell, John Walter, Andreas Hahn, Lida Zoetekouw, Antonia Ribes, Suzanne Lind, Raoul C. M. Hennekam:
Dihydropyrimidinase deficiency: Phenotype, genotype and structural consequences in 17 patients.
doi:10.1016/j.bbadis.2010.03.013 PMID
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A. B. P. van Kuilenburg, J. Meijer, G. Gökcay, T. Baykal, M. E. Rubio-Gozalbo, A. N. P. M. Mul, C. E. M. de Die-Smulders, P. Weber, A. Capone Mori, J. Bierau, B. Fowler, K. Macke, J. O. Sass, R. Meinsma, J. B. Hennermann, P. Miny, L. Zoetekouw, J. Roelofsen, R. Vijzelaar, J. Nicolai, R. C. M. Hennekam:
Dihydropyrimidine Dehydrogenase Deficiency Caused by a Novel Genomic Deletion c.505_513del of DPYD.
doi:10.1080/15257771003730227 PMID
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Anna Tylki-Szymanska, Wanda Gradowska, Anke Sommer, Angelina Heer, Melanie Walter, Christina Reinhard, Heymut Omran, Jörn Oliver Sass, Agnieszka Jurecka:
Aminoacylase 1 deficiency associated with autistic behavior.
doi:10.1007/s10545-010-9089-3 PMID
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Sabine Scholl-Bürgi, Jörn Oliver Sass, Peter Heinz-Erian, Edda Amann, Edda Haberlandt, Ursula Albrecht, Claudia Ertl, Sara Baumgartner Sigl, Florian Lagler, Kevin Rostasy, Daniela Karall:
Changes in plasma amino acid concentrations with increasing age in patients with propionic acidemia.
doi:10.1007/s00726-009-0356-2 PMID
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Jörn Oliver Sass, Aysegul Gunduz, Carolina Araujo Rodrigues Funayama, Baris Korkmaz, Kylvia Giselle Dantas Pinto, Beyhan Tuysuz, Letícia Yanasse Dos Santos, Emine Taskiran, Marlene de Fátima Turcato, Ching-Wan Lam, Jochen Reiss, Melanie Walter, Cengiz Yalcinkaya, José Simon Camelo Junior:
Functional deficiencies of sulfite oxidase: Differential diagnoses in neonates presenting with intractable seizures and cystic encephalomalacia.
doi:10.1016/j.braindev.2009.09.005 PMID
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Jörn Oliver Sass, Kathleen Fischer, Raymond Wang, Ernst Christensen, Sabine Scholl-Bürgi, Richard Chang, Klaus Kapelari, Melanie Walter:
D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK).
doi:10.1002/humu.21375 PMID
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Katharina Rauschenberger, Katja Schöler, Jörn Oliver Sass, Sven Sauer, Zdenka Djuric, Cordula Rumig, Nicole I. Wolf, Jürgen G. Okun, Stefan Kölker, Heinz Schwarz, Christine Fischer, Beate Grziwa, Heiko Runz, Astrid Nümann, Naeem Shafqat, Kathryn L. Kavanagh, Günter Hämmerling, Ronald J. A. Wanders, Julian P. H. Shield, Udo Wendel, David Stern, Peter Nawroth, Georg F. Hoffmann, Claus R. Bartram, Bernd Arnold, Angelika Bierhaus, Udo Oppermann, Herbert Steinbeisser, Johannes Zschocke:
A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.
doi:10.1002/emmm.200900055 PMID
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Manuela Popek, Melanie Walter, Malkanthi Fernando, Martin Lindner, Karl Otfried Schwab, Jörn Oliver Sass:
Two inborn errors of metabolism in a newborn: glutaric aciduria type I combined with isobutyrylglycinuria.
doi:10.1016/j.cca.2010.09.006 PMID
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N. Janzen, S. Sander, M. Terhardt, A. M. Das, J. O. Sass, R. Kraetzner, H. Rosewich, H. Rosevich, M. Peter, J. Sander:
Rapid quantification of conjugated and unconjugated bile acids and C27 precursors in dried blood spots and small volumes of serum.
doi:10.1194/jlr.D003814 PMID
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I. Höliner, B. Simma, A. Reiter, J. O. Sass, J. Zschocke, M. Huemer:
Compliance to clinical guidelines determines outcome in glutaric aciduria type I in the era of newborn screening.
doi:10.1055/s-0029-1239525 PMID
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Sarah Grünert, Miriam Schmidts, Sybille Kenzel, Jörn Oliver Sass, Peter Greiner, Martin Pohl, Roland Hentschel:
D-lactic acidosis: "right-left disorientation" in laboratory testing: acute encephalopathy in a child with carbohydrate malabsorption syndrome.
doi:10.1097/MPG.0b013e3181c48cde PMID
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Thomas Steger-Hartmann, Rainer Hofmeister, Rainer Ernst, Hubertus Pietsch, Martin A. Sieber, Jacob Walter:
A review of preclinical safety data for magnevist (gadopentetate dimeglumine) in the context of nephrogenic systemic fibrosis.
doi:10.1097/RLI.0b013e3181e960c9 PMID
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Gregor Jost, Hubertus Pietsch, Philipp Lengsfeld, Joachim Hütter, Martin A. Sieber:
The impact of the viscosity and osmolality of iodine contrast agents on renal elimination.
doi:10.1097/RLI.0b013e3181d4a036 PMID
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Florian F. Behrendt, Hubertus Pietsch, Gregor Jost, Martin A. Sieber, Sebastian Keil, Cedric Plumhans, Peter Seidensticker, Rolf W. Günther, Andreas H. Mahnken:
Intra-individual comparison of different contrast media concentrations (300 mg, 370 mg and 400 mg iodine) in MDCT.
doi:10.1007/s00330-010-1717-7 PMID
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Richard Jäger, Ralf M. Zwacka:
The enigmatic roles of caspases in tumor development.
doi:10.3390/cancers2041952 PMID
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Verena Thewes, Francesca Orso, Richard Jäger, Dawid Eckert, Sabine Schäfer, Gregor Kirfel, Stephan Garbe, Daniela Taverna, Hubert Schorle:
Interference with activator protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells.
doi:10.1186/1471-2407-10-192 PMID
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Richard Jäger, Sabine Schäfer, Mathilde Hau-Liersch, Hubert Schorle:
Loss of transcription factor AP-2gamma/TFAP2C impairs branching morphogenesis of the murine mammary gland.
doi:10.1002/dvdy.22239 PMID
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2009
Anjana Singh, Miri Blank, Yehuda Shoenfeld, Harald Illges:
Antiphospholipid Syndrome Patients Display Reduced Titers of Soluble CD21 in Their Sera Irrespective of Circulating Anti-β2-Glycoprotein-I Autoantibodies.
doi:10.1007/978-3-7908-2127-7_30
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Narendiran Rajasekaran, Samuel Solomon, Takeshi Watanabe, Hiroshi Ohtsu, Mieczyslaw Gajda, Rolf Bräuer, Harald Illges:
Histidine decarboxylase but not histamine receptor 1 or 2 deficiency protects from K/BxN serum-induced arthritis.
doi:10.1093/intimm/dxp092 PMID
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Mike Kienbaum, Cornelia Koy, Helen V. Montgomery, Susanne Drynda, Peter Lorenz, Harald Illges, Koichi Tanaka, Joern Kekow, Reinhard Guthke, Hans-Juergen Thiesen, Michael O. Glocker:
MS characterization of apheresis samples from rheumatoid arthritis patients for the improvement of immunoadsorption therapy – a pilot study.
doi:10.1002/prca.200800232 PMID
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Melanie M. Hoefer, Harald Illges:
Ectodomain shedding and generation of two carboxy-terminal fragments of human complement receptor 2/CD21.
doi:10.1016/j.molimm.2009.04.036 PMID
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Mike Althaus, Martin Fronius, Yasmin Buchaeckert, Istvan Vadasz, Wolfgang G. Clauss, Werner Seeger, Roberto Motterlini, Rory E. Morty:
Carbon Monoxide Rapidly Impairs Alveolar Fluid Clearance by Inhibiting Epithelial Sodium Channels.
doi:10.1165/rcmb.2008-0458OC PMID
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Wolfgang Heiden, Rainer Herpers, André Hinkenjann:
Visual Computing an der FH Bonn-Rhein-Sieg.
doi:10.1007/978-3-7908-2127-7_7
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Rainer Herpers, Wolfgang Heiden, Michael Kutz, David Scherfgen, Ulrich Hartmann, Jens Bongartz, Oliver Schulzyk:
FIVIS – Bicycle Simulator in the Immersive Visualisation Environment "Immersion Square".
doi:10.1007/978-3-7908-2127-7_6
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Rainer Herpers, Wolfgang Heiden, Michael Kutz, David Scherfgen:
Immersion Square - A Cost-Effective Multi-Screen VR Visualisation Technology.
BibTeX | RIS
M. Turek, W. Heiden, A. Riesen, T. A. Chhabda, J. Schubert, W. Zander, P. Krüger, M. Keusgen, M. J. Schöning:
Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors.
doi:10.1016/j.electacta.2009.03.035
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Christian Weiland, Anne-Kathrin Braun, Wolfgang Heiden:
Colorimetric and Photometric Compensation for Optical See-Through Displays.
doi:10.1007/978-3-642-02710-9_67
BibTeX | RIS
André B. P. van Kuilenburg, Judith Meijer, Adri N. P. M. Mul, Raoul C. M. Hennekam, Jan M. N. Hoovers, Christine E. M. de Die-Smulders, Peter Weber, Andrea Capone Mori, Jörgen Bierau, Brian Fowler, Klaus Macke, Jörn Oliver Sass, Rutger Meinsma, Julia B. Hennermann, Peter Miny, Lida Zoetekouw, Raymon Vijzelaar, Joost Nicolai, Bauke Ylstra, M. Estela Rubio-Gozalbo:
Analysis of severely affected patients with dihydropyrimidine dehydrogenase deficiency reveals large intragenic rearrangements of DPYD and a de novo interstitial deletion del(1)(p13.3p21.3).
doi:10.1007/s00439-009-0653-6 PMID
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Jörn Oliver Sass, Janet S. Romrell, Sarah Y. Vinson, Hubert H. Fernandez, Judith Fischer, Ramon L. Rodriguez, Michael S. Okun:
Tracing the origin of L-2-hydroxyglutaric aciduria in a family.
doi:10.1080/00207450903139655 PMID
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Hala Mégarbané, Jobard Florence, Jörn Oliver Sass, Susanne Schwonbeck, Mario Foglio, Rafael de Cid, Susan Cure, Safa Saker, André Mégarbané, Judith Fischer:
An autosomal-recessive form of cutis laxa is due to homozygous elastin mutations, and the phenotype may be modified by a heterozygous fibulin 5 polymorphism.
doi:10.1038/jid.2008.450 PMID
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G. Haliloglu, C. M. Temucin, K. K. Oguz, A. Celiker, T. Coskun, J. O. Sass, J. Fischer, M. Topcu:
Peripheral neuropathy in a patient with D-2-hydroxyglutaric aciduria.
doi:10.1007/s10545-009-0933-2 PMID
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Berend Feddersen, Larissa de La Fontaine, Jörn Oliver Sass, Jurgen Lutz, Angela Abicht, Thomas Klopstock, Ishwar Chander Verma, Eva Meisenzahl, Oliver Pogarell:
Mitochondrial neurogastrointestinal encephalomyopathy mimicking anorexia nervosa.
doi:10.1176/appi.ajp.2008.08101525 PMID
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Afshin Borhani Haghighi, Ali Nabavizadeh, Jörn Oliver Sass, Anahid Safari, Kamran B. Lankarani:
Mitochondrial neurogastrointestinal encephalomyopathy.
PMID
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Martin A. Sieber:
Pharmaceutical and safety aspects of gadolinium-based contrast agents.
BibTeX | RIS
Martin A. Sieber, Thomas Steger-Hartmann, Philipp Lengsfeld, Hubertus Pietsch:
Gadolinium-based contrast agents and NSF: evidence from animal experience.
doi:10.1002/jmri.21971 PMID
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Hubertus Pietsch, Christiane Pering, Philipp Lengsfeld, Jakob Walter, Thomas Steger-Hartmann, Sven Golfier, Thomas Frenzel, Joachim Hütter, Hans-Joachim Weinmann, Martin A. Sieber:
Evaluating the role of zinc in the occurrence of fibrosis of the skin: a preclinical study.
doi:10.1002/jmri.21845 PMID
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Hubertus Pietsch, Philipp Lengsfeld, Thomas Steger-Hartmann, Andrea Löwe, Thomas Frenzel, Joachim Hütter, Martin A. Sieber:
Impact of renal impairment on long-term retention of gadolinium in the rodent skin following the administration of gadolinium-based contrast agents.
doi:10.1097/RLI.0b013e3181998eb7 PMID
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Gregor Jost, Hubertus Pietsch, Janine Sommer, Peter Sandner, Philipp Lengsfeld, Peter Seidensticker, Stephan Lehr, Joachim Hütter, Martin A. Sieber:
Retention of iodine and expression of biomarkers for renal damage in the kidney after application of iodinated contrast media in rats.
doi:10.1097/RLI.0b013e318190fbd2 PMID
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Hubertus Pietsch, Philipp Lengsfeld, Gregor Jost, Thomas Frenzel, Joachim Hütter, Martin A. Sieber:
Long-term retention of gadolinium in the skin of rodents following the administration of gadolinium-based contrast agents.
doi:10.1007/s00330-008-1259-4 PMID
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Robert Storm, Justyna Cholewa-Waclaw, Katja Reuter, Dominique Bröhl, Martin Sieber, Mathias Treier, Thomas Müller, Carmen Birchmeier:
The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei.
doi:10.1242/dev.027193 PMID
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T. Steger-Hartmann, M. Raschke, B. Riefke, H. Pietsch, M. A. Sieber, J. Walter:
The involvement of pro-inflammatory cytokines in nephrogenic systemic fibrosis - a mechanistic hypothesis based on preclinical results from a rat model treated with gadodiamide.
doi:10.1016/j.etp.2008.11.004 PMID
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Andreas H. Mahnken, Gregor Jost, Philipp Bruners, Martin Sieber, Peter R. Seidensticker, Rolf W. Günther, Hubertus Pietsch:
Multidetector computed tomography (MDCT) evaluation of myocardial viability: intraindividual comparison of monomeric vs. dimeric contrast media in a rabbit model.
doi:10.1007/s00330-008-1150-3 PMID
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Patricia Kurth, Anne Moenning, Richard Jäger, Gaby Beine, Hubert Schorle:
An activating mutation in the PDGF receptor alpha results in embryonic lethality caused by malformation of the vascular system.
doi:10.1002/dvdy.21939 PMID
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Francesca Orso, Richard Jäger, Raffaele Adolfo Calogero, Hubert Schorle, Piero Sismondi, Michele de Bortoli, Daniela Taverna:
AP-2alpha regulates migration of GN-11 neurons via a specific genetic programme involving the Axl receptor tyrosine kinase.
doi:10.1186/1741-7007-7-25 PMID
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Anne Moenning, Richard Jäger, Angela Egert, Wolfram Kress, Eva Wardelmann, Hubert Schorle:
Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway.
doi:10.1128/MCB.00885-08 PMID
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Lawrence Rajendran, Julia Beckmann, Astrid Magenau, Eva-Maria Boneberg, Katharina Gaus, Antonella Viola, Bernd Giebel, Harald Illges:
Flotillins Are Involved in the Polarization of Primitive and Mature Hematopoietic Cells.
PDF Download (CC BY 3.0) doi:10.1371/journal.pone.0008290 PMID urn:nbn:de:hbz:1044-opus-36792
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Eva-Maria Boneberg, Harald Illges, Daniel F. Legler, Gregor Fürstenberger:
Soluble CD146 is generated by ectodomain shedding of membrane CD146 in a calcium-induced, matrix metalloprotease-dependent process.
doi:10.1016/j.mvr.2009.06.012 PMID
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2008
Johannes Schenkel, Hans Weiher, Gerhard Fürstenberger, Richard Jäger:
Suprabasal BCL-2 Expression Does Not Sensitize to Chemically-induced Skin Cancer in Transgenic Mice.
URL PMID
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Anjana Singh, Miri Blank, Yehuda Shoenfeld, Harald Illges:
Antiphospholipid syndrome patients display reduced titers of soluble CD21 in their sera irrespective of circulating anti-β2-glycoprotein-I autoantibodies.
doi:10.1007/s00296-007-0503-6 PMID
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Madhan Masilamani, Narendiran Rajasekaran, Anjana Singh, Hui-Zhi Low, Kerstin Albus, Swantje Anders, Frank Behne, Peter Eiermann, Katharina Koenig, Clarissa Mindnich, Teodora Ribarska, Harald Illges:
Systemic reduction of soluble complement receptor II/CD21 during pregnancy to levels reminiscent of autoimmune disease.
doi:10.1007/s00296-008-0604-x PMID
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Robert Pesch, Artem Lysenko, Matthew Hindle, Keywan Hassani-Pak, Ralf Thiele, Christopher Rawlings, Jacob Köhler, Jan Taubert:
Graph-based sequence annotation using a data integration approach.
PDF Download (CC BY-NC-ND 3.0) doi:10.2390/biecoll-jib-2008-94 PMID doi:10.1515/jib-2008-94 urn:nbn:de:hbz:1044-opus-5283
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R. Herpers, W. Heiden, M. Kutz, D. Scherfgen, U. Hartmann, J. Bongartz, O. Schulzyk:
FIVIS Bicycle Simulator - An Immersive Game Plattform for Physical Activities.
doi:10.1145/1496984.1497035
BibTeX | RIS
Christian Weiland, Anne-Kathrin Braun, Wolfgang Heiden:
Colorimetric and Photometric Compensation for See-Through Displays.
doi:10.1145/1400885.1400951
BibTeX | RIS
S. Scholl-Bürgi, S. H. Korman, D. A. Applegarth, D. Karall, Y. Lillquist, P. Heinz-Erian, A. G. F. Davidson, E. Haberlandt, J. O. Sass:
The relation of cerebrospinal fluid and plasma glycine levels in propionic acidaemia, a 'ketotic hyperglycinaemia'.
doi:10.1007/s10545-008-0796-y PMID
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Jörn Oliver Sass, Regina Ensenauer, Wulf Röschinger, Horst Reich, Ulrike Steuerwald, Oliver Schirrmacher, Katharina Engel, Johannes Häberle, Brage Storstein Andresen, André Mégarbané, Willy Lehnert, Johannes Zschocke:
2-Methylbutyryl-coenzyme A dehydrogenase deficiency: functional and molecular studies on a defect in isoleucine catabolism.
doi:10.1016/j.ymgme.2007.09.002 PMID
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J. O. Sass, F. Jobard, M. Topçu, A. Mahfoud, E. Werlé, S. Cure, N. Al-Sannaa, S. A. Alshahwan, M. Bataillard, L. Cimbalistiene, C. Grolik, V. Kemmerich, H. Omran, L. Sztriha, M. Tabache, J. Fischer:
L-2-hydroxyglutaric aciduria: identification of ten novel mutations in the L2HGDH gene.
doi:10.1007/s10545-008-0855-4 PMID
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G. Haliloglu, F. Jobard, K. K. Oguz, B. Anlar, N. Akalan, T. Coskun, J. O. Sass, J. Fischer, M. Topcu:
L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene: neuroimaging findings.
doi:10.1055/s-2008-1081217 PMID
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Udo F. H. Engelke, Jörn Oliver Sass, Rudy N. van Coster, Erik Gerlo, Heike Olbrich, Stefan Krywawych, Jacqui Calvin, Claire Hart, Heymut Omran, Ron A. Wevers:
NMR spectroscopy of aminoacylase 1 deficiency, a novel inborn error of metabolism.
doi:10.1002/nbm.1170 PMID
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M. A. Sieber, P. Lengsfeld, H. Pietsch:
Response to editorial: animal models for nephrogenic systemic fibrosis.
doi:10.1080/02841850802402096 PMID
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Martin A. Sieber, Philipp Lengsfeld, Thomas Frenzel, Sven Golfier, Heribert Schmitt-Willich, Fred Siegmund, Jakob Walter, Hanns-Joachim Weinmann, Hubertus Pietsch:
Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions.
doi:10.1007/s00330-008-0977-y PMID
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Martin A. Sieber, Philipp Lengsfeld, Jakob Walter, Heiko Schirmer, Thomas Frenzel, Fred Siegmund, Hanns-Joachim Weinmann, Hubertus Pietsch:
Gadolinium-based contrast agents and their potential role in the pathogenesis of nephrogenic systemic fibrosis: the role of excess ligand.
doi:10.1002/jmri.21368 PMID
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Martin A. Sieber, Hubertus Pietsch, Jakob Walter, Wolfram Haider, Thomas Frenzel, Hanns-Joachim Weinmann:
A preclinical study to investigate the development of nephrogenic systemic fibrosis: a possible role for gadolinium-based contrast media.
doi:10.1097/RLI.0b013e31815e6277 PMID
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Richard Jäger, Leontios Pappas, Hubert Schorle:
Lactogenic differentiation of HC11 cells is not accompanied by downregulation of AP-2 transcription factor genes.
doi:10.1186/1756-0500-1-29 PMID
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Melanie M. Hoefer, Annette Aichem, Andrew M. Knight, Harald Illges:
Modulation of murine complement receptor type 2 (CR2/CD21) ectodomain shedding by its cytoplasmic domain.
doi:10.1016/j.molimm.2007.12.015 PMID
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Wolfgang Heiden:
Ein Edutainment-Konzept für die akademische Lehre.
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Wolfgang Heiden:
Sensor-Analyse mit Fuzzy Logic.
BibTeX | RIS
M. Turek, W. Heiden, T. A. Chhabda, A. Riesen, P. Krüger, M. Keusgen, M. J. Schöning:
Artificial Intelligence/Fuzzy Logic Methods for Analysis of Combined Signals from Heavy Metal Chemical Sensors.
BibTeX | RIS
2007
Mike Althaus, Roman Bogdan, Wolfgang G. Clauss, Martin Fronius:
Mechano-sensitivity of epithelial sodium channels (ENaCs): laminar shear stress increases ion channel open probability.
doi:10.1096/fj.06-7694com PMID
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Hans Weiher, Ralf M. Zwacka:
Vitamin D3-24-Hydroxylase (CYP24) as a Potential Target for Intervention with Diabetic and Nondiabetic Nephropathy.
PMID
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Manfred Kneilling, Lothar Hueltner, Bernd J. Pichler, Reinhard Mailhammer, Lars Morawietz, Samuel Solomon, Martin Eichner, Joseph Sabatino, Tilo Biedermann, Veit Krenn, Wolfgang A. Weber, Harald Illges, Roland Haubner, Martin Roecken:
Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice.
doi:10.1002/art.22602 PMID
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Ralf Schiewek, Michaela Wirtz, Markus Thiemann, Kay Plitt, Gunter Vogt, Oliver J. Schmitz:
Determination of the DNA methylation level of the marbled crayfish: an increase in sample throughput by an optimised sample preparation.
doi:10.1016/j.jchromb.2006.11.040 PMID
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Markus Lanser, Axel Hau, Wolfgang Heiden, Rainer Herpers:
GL-Wrapper for Stereoscopic Rendering of Standard Applications for a PC-based Immersive Environment.
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Wolfgang Heiden:
An Edutainment Approach to Academic Teaching.
BibTeX | RIS
J. O. Sass, H. Olbrich, V. Mohr, C. Hart, B. Woldseth, S. Krywawych, B. Bjurulf, P. K. Lakhani, R. M. Buchdahl, H. Omran:
Neurological findings in aminoacylase 1 deficiency.
doi:10.1212/01.wnl.0000264933.56204.e8 PMID
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Daniela Baumgartner, Sabine Scholl-Bürgi, Jörn Oliver Sass, Wolfgang Sperl, Ulrich Schweigmann, Jörg-Ingolf Stein, Daniela Karall:
Prolonged QTc intervals and decreased left ventricular contractility in patients with propionic acidemia.
doi:10.1016/j.jpeds.2006.11.043 PMID
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Martin A. Sieber, Robert Storm, Margaret Martinez-de-la-Torre, Thomas Müller, Hagen Wende, Katja Reuter, Elena Vasyutina, Carmen Birchmeier:
Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain.
doi:10.1523/JNEUROSCI.0717-07.2007 PMID
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Lawrence Rajendran, Soazig Le Lay, Harald Illges:
Raft association and lipid droplet targeting of flotillins are independent of caveolin.
doi:10.1515/BC.2007.034 PMID
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Jochen Maurer, Sebastian Fuchs, Richard Jäger, Bodo Kurz, Lukas Sommer, Hubert Schorle:
Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis.
doi:10.1111/j.1432-0436.2007.00164.x PMID
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Michael Peitz, Richard Jäger, Christoph Patsch, Andrea Jäger, Angela Egert, Hubert Schorle, Frank Edenhofer:
Enhanced purification of cell-permeant Cre and germline transmission after transduction into mouse embryonic stem cells.
doi:10.1002/dvg.20321 PMID
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Richard Jäger:
Targeting the death machinery in mammary epithelial cells: Implications for breast cancer from transgenic and tissue culture experiments.
doi:10.1016/j.critrevonc.2007.05.006 PMID
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J. Brauers, M. Kresken, A. Menke, A. Orland, H. Weiher, I. Morrissey:
Bactericidal activity of daptomycin, vancomycin, teicoplanin and linezolid against Staphylococcus aureus, Enterococcus faecalis and Enterococcus faecium using human peak free serum drug concentrations.
doi:10.1016/j.ijantimicag.2006.10.003 PMID
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2006
Stefan Hiendleder, Michaela Wirtz, Cora Mund, Martina Klempt, Horst-Dieter Reichenbach, Miodrag Stojkovic, Myriam Weppert, Hendrik Wenigerkind, Martin Elmlinger, Frank Lyko, Oliver J. Schmitz, Eckhard Wolf:
Tissue-specific effects of in vitro fertilization procedures on genomic cytosine methylation levels in overgrown and normal sized bovine fetuses.
doi:10.1095/biolreprod.105.043919 PMID
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Antonella Spinazzola, Carlo Viscomi, Erika Fernandez-Vizarra, Franco Carrara, Pio D'Adamo, Sarah Calvo, René Massimiliano Marsano, Claudia Donnini, Hans Weiher, Pietro Strisciuglio, Rossella Parini, Emmanuelle Sarzi, Alicia Chan, Salvatore DiMauro, Agnes Rötig, Paolo Gasparini, Iliana Ferrero, Vamsi K. Mootha, Valeria Tiranti, Massimo Zeviani:
MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion.
doi:10.1038/ng1765 PMID
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J. Brauers, M. Kresken, V. Dahmen, A. Menke, H. Weiher, I. Morrissey:
Evaluation of daptomycin, vancomycin, teicoplanin and linezolid against Staphylococcus aureus, Enterococcus faecalis and Enterococcus faecium utilizing in-vitro time-kill methodology.
URL
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Jörn Oliver Sass:
Laboratory diagnosis of sulphite oxidase deficiency.
doi:10.1007/s00431-006-0122-3 PMID
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Jörn Oliver Sass, Verena Mohr, Heike Olbrich, Udo Engelke, Judit Horvath, Manfred Fliegauf, Niki Tomas Loges, Susanne Schweitzer-Krantz, Ralf Moebus, Polly Weiler, Andreas Kispert, Andrea Superti-Furga, Ron A. Wevers, Heymut Omran:
Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism.
doi:10.1086/500563 PMID
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Ronny Jung, Anita Rauch, Gajja S. Salomons, Nanda M. Verhoeven, Cornelis Jakobs, K. Michael Gibson, Ehrenfried Lachmann, Jörn Oliver Sass, Udo Trautmann, Christiane Zweier, Gundula Staatz, Ina Knerr:
Clinical, cytogenetic and molecular characterization of a patient with combined succinic semialdehyde dehydrogenase deficiency and incomplete WAGR syndrome with obesity.
doi:10.1016/j.ymgme.2006.02.003 PMID
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Susen Hartmann, Jürgen G. Okun, Christiane Schmidt, Claus-Dieter Langhans, Sven F. Garbade, Peter Burgard, Dorothea Haas, Jörn Oliver Sass, William L. Nyhan, Georg F. Hoffmann:
Comprehensive detection of disorders of purine and pyrimidine metabolism by HPLC with electrospray ionization tandem mass spectrometry.
doi:10.1373/clinchem.2005.058842 PMID
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Sarah Sengstake, Eva-Maria Boneberg, Harald Illges:
CD21 and CD62L shedding are both inducible via P2X7Rs.
doi:10.1093/intimm/dxl051 PMID
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Eva-Maria Boneberg, Elisabeth von Seydlitz, Karl Pröpster, Hans Watzl, Brigitte Rockstroh, Harald Illges:
D3 dopamine receptor mRNA is elevated in T cells of schizophrenic patients whereas D4 dopamine receptor mRNA is reduced in CD4+ -T cells.
doi:10.1016/j.jneuroim.2005.11.018 PMID
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Wolfgang Heiden, Arjang Ostovar:
Structuring Hypermedia Novels.
doi:10.1007/11944577_10
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Wolfgang Heiden:
Frühzeitige Diagnostik der peripheren arteriellen Verschlusskrankheit mit Hilfe von Thermographischer Visualisierung.
BibTeX | RIS
Wolfgang Heiden:
Edutainment Aspects in Hypermedia Storytelling.
doi:10.1007/11736639_50
BibTeX | RIS
Rita Cornely, Wolfgang Heiden, Michael Wiese:
Hydrogen bond potential in molecular modeling.
BibTeX | RIS
Thomas Grottenthaler, Johannes von Kempis, Sigune Goldacker, Harald Illges:
Soluble CD21 in sera and synovial fluid of arthritic patients.
doi:10.1007/s00296-004-0541-2 PMID
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Annette Aichem, Madhan Masilamani, Harald Illges:
Redox regulation of CD21 shedding involves signaling via PKC and indicates the formation of a juxtamembrane stalk.
doi:10.1242/jcs.02984 PMID
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Melanie M. Hoefer, Eva-Maria Boneberg, Stefan Grotegut, Justine Kusch, Harald Illges:
Possible tetramerisation of the proteasome maturation factor POMP/proteassemblin/hUmp1 and its subcellular localisation.
doi:10.1016/j.ijbiomac.2006.03.015 PMID
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Eric Fassbender, Wolfgang Heiden:
The Virtual Memory Palace.
BibTeX | RIS
2005
Martin Corcoran, Anton Parker, Jenny Orchard, Zadie Davis, Michaela Wirtz, Oliver J. Schmitz, David Oscier:
ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia.
URL PMID
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Michaela Wirtz, Claus A. Schumann, Marc Schellentrager, Siegmar Gab, Jochen Vom Brocke, Michael A. L. Podeschwa, Hans-J Altenbach, David Oscier, Oliver J. Schmitz:
Capillary electrophoresis-laser induced fluorescence analysis of endogenous damage in mitochondrial and genomic DNA.
doi:10.1002/elps.200410397 PMID
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U. Tacke, H. Olbrich, J. O. Sass, A. Fekete, J. Horvath, S. Ziyeh, W. J. Kleijer, M-O Rolland, S. Fisher, S. Payne, E. Vargiami, D. I. Zafeiriou, H. Omran:
Possible genotype-phenotype correlations in children with mild clinical course of Canavan disease.
doi:10.1055/s-2005-865865 PMID
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Jörn Oliver Sass, Andrea Superti-Furga:
Gamma-hydroxybutyric acid.
doi:10.1056/NEJMc052046 PMID
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Jochen Reiss, Michael Bonin, Herbert Schwegler, Jörn Oliver Sass, Enrico Garattini, Silke Wagner, Heon-Jin Lee, Wolfgang Engel, Olaf Riess, Günter Schwarz:
The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis.
doi:10.1016/j.ymgme.2005.01.008 PMID
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Willy Lehnert, Jörn Oliver Sass:
Glutaconyl-CoA is the main toxic agent in glutaryl-CoA dehydrogenase deficiency (glutaric aciduria type I).
doi:10.1016/j.mehy.2005.02.021 PMID
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Martina Huemer, Burkhard Simma, Brian Fowler, Terttu Suormala, Olaf A. Bodamer, Jörn Oliver Sass:
Prenatal and postnatal treatment in cobalamin C defect.
doi:10.1016/j.jpeds.2005.04.040 PMID
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Maria Haller, Angelika Henzler-Le Boulanger, Jörn Oliver Sass, Matthias Brandis, Lothar Bernd Zimmerhackl:
Successful extracorporeal treatment of a male with hyperammonaemic coma.
doi:10.1093/ndt/gfh495 PMID
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Gunther Spohn, Katrin Schwarz, Patrik Maurer, Harald Illges, Narendiran Rajasekaran, Yongwon Choi, Gary T. Jennings, Martin F. Bachmann:
Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles.
doi:10.4049/jimmunol.175.9.6211 PMID
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Hong-gang Hu, Harald Illges, Claudia Gruss, Rolf Knippers:
Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes.
doi:10.1093/intimm/dxh261 PMID
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Steffen Möller, Eilhard Mix, Martin Blüggel, Pablo Serrano-Fernández, Dirk Koczan, Vasilis Kotsikoris, Manfred Kunz, Michael Watson, Jens Pahnke, Harald Illges, Michael Kreutzer, Stefan Mikkat, Hans-Jürgen Thiesen, Michael O. Glocker, Uwe K. Zettl, Saleh M. Ibrahim:
Collection of soluble variants of membrane proteins for transcriptomics and proteomics.
URL PMID
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Dawid Eckert, Sandra Buhl, Susanne Weber, Richard Jäger, Hubert Schorle:
The AP-2 family of transcription factors.
doi:10.1186/gb-2005-6-13-246 PMID
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Richard Jäger, Jens Hahne, Andrea Jacob, Angela Egert, Johannes Schenkel, Nicolas Wernert, Hubert Schorle, Axel Wellmann:
Mice transgenic for NPM-ALK develop non-Hodgkin lymphomas.
URL PMID
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Richard Jennemann, Roger Sandhoff, Shijun Wang, Eva Kiss, Norbert Gretz, Cecilia Zuliani, Ana Martin-Villalba, Richard Jäger, Hubert Schorle, Marc Kenzelmann, Mahnaz Bonrouhi, Herbert Wiegandt, Hermann-Josef Gröne:
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth.
doi:10.1073/pnas.0500893102
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Katharina Pauls, Richard Jäger, Susanne Weber, Eva Wardelmann, Arend Koch, Reinhard Büttner, Hubert Schorle:
Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors.
doi:10.1002/ijc.20913
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Richard Jäger, Nicolaus Friedrichs, Inge Heim, Reinhard Büttner, Hubert Schorle:
Dual role of AP-2gamma in ErbB-2-induced mammary tumorigenesis.
doi:10.1007/s10549-004-4815-x
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Christine Philbrook, Eberhard Fritz, Hans Weiher:
Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
doi:10.1016/j.exger.2005.06.008 PMID
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Samuel Solomon, Narendiran Rajasekaran, Elvira Jeisy-Walder, Scott B. Snapper, Harald Illges:
A crucial role for macrophages in the pathology of K/B × N serum-induced arthritis.
doi:10.1002/eji.200526167 PMID
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Samuel Solomon, Daniela Kassahn, Harald Illges:
The role of the complement and the FcγR system in the pathogenesis of arthritis.
doi:10.1186/ar1761 PMID
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Wolfgang Heiden, Rita Cornely:
Representation and Analysis of 3D Shape.
URL
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D. Schmitz, D. Seibt, R. Herpers, W. Heiden:
3D-Reconstruction of Microscopic Translucent Silicate-Based Marine and Freshwater Organisms.
BibTeX | RIS
Rainer Herpers, Florian Hetmann, Axel Hau, Wolfgang Heiden:
The Immersion Square - A Mobile Platform for Immersive Visualizations.
BibTeX | RIS
2004
Sean Michael O'Shea, Lore Becker, Hans Weiher, Heinrich Betz, Bodo Laube:
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
doi:10.1523/JNEUROSCI.4675-03.2004 PMID
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A. Mohr, G. Henderson, L. Dudus, I. Herr, T. Kuerschner, K-M Debatin, H. Weiher, K. J. Fisher, R. M. Zwacka:
AAV-encoded expression of TRAIL in experimental human colorectal cancer leads to tumor regression.
doi:10.1038/sj.gt.3302154 PMID
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Damayanti R. Sjarif, Christina Hellerud, Johannes K. Ploos van Amstel, Willem J. Kleijer, Wolfgang Sperl, Didier Lacombe, Jörn Oliver Sass, Frits A. Beemer, Marinus Duran, Bwee Tien Poll-The:
Glycerol kinase deficiency: residual activity explained by reduced transcription and enzyme conformation.
doi:10.1038/sj.ejhg.5201172 PMID
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Günter Schwarz, José Angel Santamaria-Araujo, Stefan Wolf, Heon-Jin Lee, Ibrahim M. Adham, Hermann-Josef Gröne, Herbert Schwegler, Jörn Oliver Sass, Tanja Otte, Petra Hänzelmann, Ralf R. Mendel, Wolfgang Engel, Jochen Reiss:
Rescue of lethal molybdenum cofactor deficiency by a biosynthetic precursor from Escherichia coli.
doi:10.1093/hmg/ddh136 PMID
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Jörn Oliver Sass, Toyofumi Nakanishi, Takako Sato, Akira Shimizu:
New approaches towards laboratory diagnosis of isolated sulphite oxidase deficiency.
doi:10.1258/000456304322880078 PMID
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Jörn Oliver Sass, Rosemarie Forstner, Wolfgang Sperl:
2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency: impaired catabolism of isoleucine presenting as neurodegenerative disease.
doi:10.1016/S0387-7604(03)00071-8 PMID
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J. O. Sass, D. Skladal, B. Zelger, N. Romani, B. Utermann:
Trichothiodystrophy: quantification of cysteine in human hair and nails by application of sodium azide-dependent oxidation to cysteic acid.
doi:10.1007/s00403-004-0483-2 PMID
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J. O. Sass, S. Sander, J. Zschocke:
Isobutyryl-CoA dehydrogenase deficiency: isobutyrylglycinuria and ACAD8 gene mutations in two infants.
doi:10.1023/B:BOLI.0000045798.12425.1b PMID
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J. O. Sass, M. Hofmann, D. Skladal, E. Mayatepek, B. Schwahn, W. Sperl:
Propionic acidemia revisited: a workshop report.
doi:10.1177/000992280404300908 PMID
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Regina Ensenauer, Jerry Vockley, Jan-Marie Willard, Joseph C. Huey, Jörn Oliver Sass, Steven D. Edland, Barbara K. Burton, Susan A. Berry, René Santer, Sarah Grünert, Hans-Georg Koch, Iris Marquardt, Piero Rinaldo, Sihoun Hahn, Dietrich Matern:
A common mutation is associated with a mild, potentially asymptomatic phenotype in patients with isovaleric acidemia diagnosed by newborn screening.
doi:10.1086/426318 PMID
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M. Masilamani, R. Nowack, T. Witte, M. Schlesier, K. Warnatz, M. O. Glocker, H. H. Peter, H. Illges:
Reduction of soluble complement receptor 2/CD21 in systemic lupus erythomatosus and Sjogren's syndrome but not juvenile arthritis.
doi:10.1111/j.0300-9475.2004.01494.x PMID
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M. V. Klett, E-M Boneberg, K. Trenz, R. Knippers, H. Illges:
Hydrostatic pressure induces apoptosis in the human leukaemic T-cell line Jurkat via the mitochondrial pathway.
doi:10.1111/j.0300-9475.2004.01496.x PMID
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Claudia Wehr, Hermann Eibel, Madhan Masilamani, Harald Illges, Michael Schlesier, Hans-Hartmut Peter, Klaus Warnatz:
A new CD21low B cell population in the peripheral blood of patients with SLE.
doi:10.1016/j.clim.2004.05.010 PMID
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Nicolaus Friedrichs, Richard Jäger, Ellen Paggen, Christian Rudlowski, Sabine Merkelbach-Bruse, Hubert Schorle, Reinhard Buettner:
Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer.
doi:10.1038/modpathol.3800292
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Richard Jäger, Jochen Maurer, Andrea Jacob, Hubert Schorle:
Cell type-specific conditional regulation of the c-myc proto-oncogene by combining Cre/loxP recombination and tamoxifen-mediated activation.
doi:10.1002/gene.20014 PMID
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V. Kemmet, W. Heiden:
Augmented Perception - AuPer.
BibTeX | RIS
2003
Jörn Oliver Sass, Toyofumi Nakanishi, Takako Sato, Wolfgang Sperl, Akira Shimizu:
S-homocysteinylation of transthyretin is detected in plasma and serum of humans with different types of hyperhomocysteinemia.
doi:10.1016/j.bbrc.2003.08.089 PMID
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J. O. Sass, M. Kishikawa, R. Puttinger, J. Reiss, W. Erwa, A. Shimizu, W. Sperl:
Hypohomocysteinaemia and highly increased proportion of S-sulfonated plasma transthyretin in molybdenum cofactor deficiency.
doi:10.1023/A:1024091900547 PMID
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Rob Ofman, Jos P. N. Ruiter, Marike Feenstra, Marinus Duran, Bwee Tien Poll-The, Johannes Zschocke, Regina Ensenauer, Willy Lehnert, Jörn Oliver Sass, Wolfgang Sperl, Ronald J. A. Wanders:
2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency is caused by mutations in the HADH2 gene.
URL PMID doi:10.1086/375116
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M. Masilamani, J. von Kempis, H. Illges:
Decreased levels of serum soluble complement receptor-II (CR2/CD21) in patients with rheumatoid arthritis.
doi:10.1093/rheumatology/keg449 PMID
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Samuel Solomon, Madhan Masilamani, Subhasis Mohanty, Jörg E. Schwab, Eva-Maria Boneberg, Harald Illges:
Generation of three-dimensional pannus-like tissues in vitro from single cell suspensions of synovial fluid cells from arthritis patients.
doi:10.1007/s00296-003-0333-0 PMID
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Madhan Masilamani, Daniela Kassahn, Stefan Mikkat, Michael O. Glocker, Harald Illges:
B cell activation leads to shedding of complement receptor type II (CR2/CD21).
doi:10.1002/eji.200323843 PMID
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Lawrence Rajendran, Madhan Masilamani, Samuel Solomon, Ritva Tikkanen, Claudia A. O. Stuermer, Helmut Plattner, Harald Illges:
Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells.
doi:10.1073/pnas.1331629100 PMID
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Subhasis Mohanty, Stefan Marcus Weiner, Reinhardt Mentele, Peter Vaith, Friedrich Lottspeich, Harald Illges:
Human IgG1/IgG3 cryoglobulin suggesting lack of allelic exclusion.
doi:10.1016/S0161-5890(03)00045-2 PMID
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Soeren-Oliver Deininger, Lawrence Rajendran, Friedrich Lottspeich, Michael Przybylski, Harald Illges, Claudia A. O. Stuermer, Alexander Reuter:
Identification of teleost Thy-1 and association with the microdomain/lipid raft reggie proteins in regenerating CNS axons.
doi:10.1016/S1044-7431(03)00028-9 PMID
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Richard Jäger, Uwe Werling, Stephan Rimpf, Andrea Jacob, Hubert Schorle:
Transcription Factor AP-2γ Stimulates Proliferation and Apoptosis and Impairs Differentiation in a Transgenic Model.
URL
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M. D. Lacher, A. Siegenthaler, Richard Jäger, Xi Yan, S. Hett, L. Xuan, S. Saurer, R. R. Lareu, A. M. Dharmarajan, R. Friis:
Role of DDC-4/sFRP-4, a secreted Frizzled-related protein, at the onset of apoptosis in mammary involution.
doi:10.1038/sj.cdd.4401197
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E. Matthes, D. Schmitz, W. Heiden:
Software-Driven Visual Depth-Perception.
BibTeX | RIS
Wolfgang Heiden:
Die Hypermedia Novel - Interaktives Erzählen im Netz.
BibTeX | RIS
2002
Lore Becker, Jorg von Wegerer, Johannes Schenkel, Hanns-Ulrich Zeilhofer, Dieter Swandulla, Hans Weiher:
Disease-specific human glycine receptor alpha1 subunit causes hyperekplexia phenotype and impaired glycine- and GABA(A)-receptor transmission in transgenic mice.
doi:10.1523/JNEUROSCI.22-07-02505.2002 PMID
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Jörn Oliver Sass, Sara Pascoe-González, Willy Lehnert:
Screening in clinical trials.
doi:10.1016/S0140-6736(02)11058-0 PMID
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Heon-Jin Lee, Ibrahim M. Adham, Günter Schwarz, Matthias Kneussel, Jörn O. Sass, Wolfgang Engel, Jochen Reiss:
Molybdenum cofactor-deficient mice resemble the phenotype of human patients.
doi:10.1093/hmg/11.26.3309 PMID
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Masahiko Kishikawa, Jörn Oliver Sass, Nobuo Sakura, Toyofumi Nakanishi, Akira Shimizu, Masanori Yoshioka:
The peak height ratio of S-sulfonated transthyretin and other oxidized isoforms as a marker for molybdenum cofactor deficiency, measured by electrospray ionization mass spectrometry.
doi:10.1016/S0925-4439(02)00156-4 PMID
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Samuel Solomon, Madhan Masilamani, Lawrence Rajendran, Martin Bastmeyer, Claudia A. O. Stuermer, Harald Illges:
The lipid raft microdomain-associated protein reggie-1/flotillin-2 is expressed in human B cells and localized at the plasma membrane and centrosome in PBMCs.
doi:10.1078/0171-2985-00114 PMID
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Rudolf Mierau, Harald Illges:
Autoantikörper und das Komplementsystem - Bedeutung für die Pathogenese der Rheumatoiden Arthritis?.
doi:10.1007/s00393-002-0435-1 PMID
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Madhan Masilamani, Elizabeth von Seydlitz, Martin Bastmeyer, Harald Illges:
T cell activation induced by cross-linking CD3 and CD28 leads to silencing of Epstein-Barr virus/C3d receptor (CR2/CD21) gene and protein expression.
doi:10.1078/0171-2985-00201 PMID
BibTeX | RIS
H. Illges:
Die Rolle der Komplementpfade, Fc-Rezeptoren und Antikörper in einem Rheumamodell.
BibTeX | RIS
Hua Shen, Harald Illges, Alexander Reuter, Claudia A. O. Stuermer:
Cloning, expression, and alternative splicing of neogenin1 in zebrafish.
doi:10.1016/S0925-4773(02)00255-1 PMID
BibTeX | RIS
Madhan Masilamani, Hans-Jürgen Apell, Harald Illges:
Purification and characterization of soluble CD21 from human plasma by affinity chromatography and density gradient centrifugation.
doi:10.1016/S0022-1759(02)00211-9 PMID
BibTeX | RIS
Daniela Kassahn, Cornelia Kolb, Samuel Solomon, Petra Bochtler, Harald Illges:
Few human autoimmune sera detect GPI.
doi:10.1038/ni0502-411b PMID
BibTeX | RIS
Samuel Solomon, Cornelia Kolb, Subhasis Mohanty, Elvira Jeisy-Walder, Rosemarie Preyer, Volkmar Schöllhorn, Harald Illges:
Transmission of antibody-induced arthritis is independent of complement component 4 (C4) and the complement receptors 1 and 2 (CD21/35).
doi:10.1002/1521-4141(200203)32:3<644::AID-IMMU644>3.0.CO;2-5 PMID
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Nadia Munarini, Richard Jäger, Susanne Abderhalden, Gisela Zuercher, Valeria Rohrbach, Saemi Loercher, Brigitte Pfanner-Meyer, Anne-Catherine Andres, Andrew Ziemiecki:
Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase.
doi:10.1242/jcs.115.1.25
BibTeX | RIS
F. Hetmann, R. Herpers, W. Heiden:
The Immersion Square - Immersive VR with Standard Components.
BibTeX | RIS
2001
G. Wagner, K. Stettmaier, W. Bors, H. Sies, E. M. Wagner, A. Reuter, H. Weiher:
Enhanced gamma-glutamyl transpeptidase expression and superoxide production in Mpv17-/- glomerulosclerosis mice.
doi:10.1515/BC.2001.128 PMID
BibTeX | RIS
Angela M. Meyer zum Gottesberge, Heidi Felix, Alexander Reuter, Hans Weiher:
Ultrastructural and physiological defects in the cochlea of the Mpv17 mouse strain.
doi:10.1016/S0378-5955(01)00268-4 PMID
BibTeX | RIS
J. O. Sass, W. Sperl, C. Bachmann:
Treatment of neonatal hyperammonaemia.
doi:10.1016/S0140-6736(01)06746-0 PMID
BibTeX | RIS
Jörn Oliver Sass, Daniela Skladal, Stephan Felber:
Update on white matter genetic disorders.
doi:10.1016/S0887-8994(01)00341-1 PMID
BibTeX | RIS
J. O. Sass, P. Heinz-Erian, W. Högler:
Increased CSF cortisol in AD is a function of APOE genotype.
doi:10.1212/WNL.57.8.1522-a PMID
BibTeX | RIS
J. O. Sass, R. Crazzolara, P. Heinz-Erian:
Mechanisms of brain injury in infantile child abuse.
doi:10.1016/S0140-6736(01)07116-1 PMID
BibTeX | RIS
Ralph Rühl, Jörn Sass, Heinz Nau, Stephan Klug:
Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity.
doi:10.1007/s002040100257 PMID
BibTeX | RIS
Jörg Schwab, Harald Illges:
Silencing of CD21 expression in synovial lymphocytes is independent of methylation of the CD21 promoter CpG island.
doi:10.1007/s002960000090 PMID
BibTeX | RIS
Jörg Schwab, Harald Illges:
Regulation of CD21 expression by DNA methylation and histone deacetylation.
doi:10.1093/intimm/13.5.705 PMID
BibTeX | RIS
Andreas Marti, Philipp M. Ritter, Richard Jäger, Hedvika Lazar, Anna Baltzer, Johannes Schenkel, Wim Declercq, Peter Vandenabeele, Rolf Jaggi:
Mouse mammary gland involution is associated with cytochrome c release and caspase activation.
doi:10.1016/S0925-4773(01)00381-1
BibTeX | RIS
Wolfgang Heiden, Christian Frühling, Harald Deuer:
Hypermedia Novel HYMN - A New Storytelling Paradigm.
URL
BibTeX | RIS
2000
H. Bürger, W. Jerzembeck, H. Ruland, M. Wirtz:
High resolution FTIR spectra of AsD 3 in the 20-1000 cm −1 region. The ground, 98, v 2 = 1 and v 4 = 1 states.
doi:10.1080/00268970009483326
BibTeX | RIS
T. O'Bryan, H. Weiher, H. G. Rennke, S. Kren, T. H. Hostetter:
Course of renal injury in the Mpv17-deficient transgenic mouse.
PMID doi:10.1681/ASN.V1161067
BibTeX | RIS
Lore Becker, Bettina Hartenstein, Johannes Schenkel, Jochen Kuhse, Heinrich Betz, Hans Weiher:
Transient neuromotor phenotype in transgenic spastic mice expressing low levels of glycine receptor beta-subunit: an animal model of startle disease.
doi:10.1046/j.1460-9568.2000.00877.x PMID
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W. Sperl, C. Murr, D. Skladal, J. O. Sass, T. Suormala, R. Baumgartner, U. Wendel:
Odd-numbered long-chain fatty acids in propionic acidaemia.
doi:10.1007/s004310050010 PMID
BibTeX | RIS
D. Skladal, J. O. Sass, H. Geiger, R. Geiger, C. Mann, P. Vreken, R. J. Wanders, R. Trawöger:
Complications in early diagnosis and treatment of two infants with long-chain fatty acid beta-oxidation defects.
URL PMID
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J. O. Sass, D. Skladal:
Plasma leptin in prepubertal patients with glycogen storage diseases.
doi:10.1055/s-2007-978585 PMID
BibTeX | RIS
J. O. Sass, D. Skladal:
Elevated plasma bile acid concentrations in two sisters with tyrosinaemia type I.
doi:10.1046/j.1440-1754.2000.00455.x PMID
BibTeX | RIS
J. O. Sass, J. Padberg:
Human isotretinoin metabolism during indinavir therapy.
doi:10.1089/08892220050141008 PMID
BibTeX | RIS
J. O. Sass, B. Jakob-Sölder, A. Heitger, G. Tzimas, M. Sarcletti:
Paronychia with pyogenic granuloma in a child treated with indinavir: the retinoid-mediated side effect theory revisited.
doi:10.1159/000018313 PMID
BibTeX | RIS
J. O. Sass, T. Arnhold, G. Tzimas, D. M. Jacobson:
Serum vitamin A is elevated in idiopathic intracranial hypertension.
doi:10.1212/WNL.54.11.2192 PMID
BibTeX | RIS
WenChieh Chen, Jörn Oliver Sass, Holger Seltmann, Heinz Nau, Constantin E. Orfanos, Christos C. Zouboulis:
Biological effects and metabolism of 9-cis-retinoic acid and its metabolite 9,13-di-cis-retinoic acid in HaCaT keratinocytes in vitro: comparison with all-trans-retinoic acid.
doi:10.1007/s004030000189 PMID
BibTeX | RIS
H. Illges, M. Braun, H. H. Peter, I. Melchers:
Reduced expression of the complement receptor type 2 (CR2, CD21) by synovial fluid B and T lymphocytes.
doi:10.1046/j.1365-2249.2000.01379.x PMID
BibTeX | RIS
Atef Allam, Harald Illges:
Calyculin A inhibits expression of CD8alpha but not CD4 in human peripheral blood T cells.
doi:10.1016/S0171-2985(00)80039-X PMID
BibTeX | RIS
Axel Denz, Hermann Eibel, Harald Illges, Georg Kienzle, Michael Schlesier, Hans-Hartmut Peter:
Impaired up-regulation of CD86 in B cells of "type A" common variable immunodeficiency patients.
doi:10.1002/(SICI)1521-4141(200004)30:4<1069::AID-IMMU1069>3.0.CO;2-M PMID
BibTeX | RIS
W. Heiden, M. Göbel:
Virtuelle Umgebungen.
BibTeX | RIS
Wolfgang Heiden, Manfred Kaul:
Internet and Broadcasting - a mutually beneficial combination.
BibTeX | RIS
1999
J. Schenkel, H. Gaissert, E. E. Protopapa, H. Weiher, L. Gissmann, A. Alonso:
The human papillomavirus type 11 upstream regulatory region triggers hair-follicle-specific gene expression in transgenic mice.
doi:10.1046/j.1523-1747.1999.00589.x PMID
BibTeX | RIS
Martine Clozel, Patrick Hess, Walter Fischli, Bernd–Michael Löffler, Ralf M. Zwacka, Alexander Reuter, Hans Weiher:
Age-dependent hypertension in Mpv17-deficient mice, a transgenic model of glomerulosclerosis and inner ear disease.
doi:10.1016/S0531-5565(99)00074-1 PMID
BibTeX | RIS
Christoph J. Binder, Hans Weiher, Markus Exner, Dontscho Kerjaschki:
Glomerular Overproduction of Oxygen Radicals in Mpv17 Gene-Inactivated Mice Causes Podocyte Foot Process Flattening and Proteinuria.
doi:10.1016/S0002-9440(10)65359-X PMID
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Christos C. Zouboulis, Holger Seltmann, Jörn Oliver Sass, Ralph Rühl, Claudia Plum, Uwe Hettmannsperger, Ulrike Blume-Peytavi, Heinz Nau, Constantin E. Orfanos:
Retinoid signaling by all-trans retinoic acid and all-trans retinoyl-beta-D-glucuronide is attenuated by simultaneous exposure of human keratinocytes to retinol.
doi:10.1046/j.1523-1747.1999.00496.x PMID
BibTeX | RIS
Jörn Oliver Sass, Georg Tzimas, Mohamed M.A. Elmazar, Heinz Nau:
Metabolism of Retinaldehyde Isomers in Pregnant Rats: 13-cis- and all-trans-Retinaldehyde, but not 9-cis-Retinaldehyde, Yield Very Similar Patterns of Retinoid Metabolites.
PMID URL
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J. O. Sass, D. Skladal, E. Viertler:
Methionine loading in a Down's syndrome patient with cerebral infarction.
doi:10.1177/000456329903600225 PMID
BibTeX | RIS
Jörn Oliver Sass, Daniela Skladal, Michaela Brunner-Krainz:
Normal ascorbic acid in cerebrospinal fluid of patients with infantile neuronal ceroid-lipofuscinosis.
doi:10.1023/A:1020613631353 PMID
BibTeX | RIS
Jörn Oliver Sass, Daniela Skladal:
Plasma concentrations and renal clearance of orotic acid in argininosuccinic acid synthetase deficiency.
doi:10.1007/s004670050726 PMID
BibTeX | RIS
Silvia Muro, Pilar Rodríguez‐Pombo, Belén Pérez, Celia Pérez‐Cerdá, Lourdes R. Desviat, Wolfgang Sperl, Daniela Skladal, Jörn Oliver Sass, Magdalena Ugarte:
Identification of novel mutations in the PCCB gene in European propionic acidemia patients.
doi:10.1002/(SICI)1098-1004(1999)14:1<89::AID-HUMU18>3.0.CO;2-5 PMID
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L. Didierjean, J. O. Sass, P. Carraux, D. Grand, O. Sorg, C. Plum, H. Nau, J. H. Saurat:
Topical 9-cis-retinaldehyde for delivery of 9-cis-retinoic acid in mouse skin.
doi:10.1111/j.1600-0625.1999.tb00371.x PMID
BibTeX | RIS
Priscilla A. Furth, Ud Bar-Peled, Minglin Li, Albert Lewis, Rodolfo Laucirica, Richard Jäger, Hans Weiher, Robert G. Russell:
Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model.
doi:10.1038/sj.onc.1203073
BibTeX | RIS
Kristen L. Murphy, Frances S. Kittrell, Jason P. Gay, Richard Jäger, Daniel Medina, Jeffrey M. Rosen:
Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.
doi:10.1038/sj.onc.1203099
BibTeX | RIS
Kristel Schorr, Minglin Li, Ud Bar-Peled, Albert Lewis, Alonso Heredia, Bernadette Lewis, C. Michael Knudson, Stanley J. Korsmeyer, Richard Jäger, Hans Weiher, Priscilla A. Furth:
Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo.
URL
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Monika Fleischmann, Thomas Sikora, Wolfgang Heiden, Wolfgang Strauss, Karsten Sikora, Josef Speier:
The Virtual Balance: An Input Device for VR Environments.
doi:10.24406/publica-fhg-290265
BibTeX | RIS
Ralf Thiele, Ralf Zimmer, Thomas Lengauer:
Protein threading by recursive dynamic programming.
doi:10.1006/jmbi.1999.2893 PMID
BibTeX | RIS
1998
Alexander Reuter, Andrea Nestl, Ralf M. Zwacka, Jan Tuckermann, Rüdiger Waldherr, Eva-Maria Wagner, Matti Höyhtyä, Angela M. Meyer zum Gottesberge, Peter Angel, Hans Weiher:
Expression of the Recessive Glomerulosclerosis Gene Mpv17 Regulates MMP-2 Expression in Fibroblasts, the Kidney, and the Inner Ear of Mice.
doi:10.1091/mbc.9.7.1675 PMID
BibTeX | RIS
Gerhard Eckel, Martin Göbel, Frank Hasenbrink, Wolfgang Heiden, Uli Lechner, Henrik Tramberend, Gerold Wesche, Jürgen Wind:
Benches and Caves.
doi:10.1109/IECON.1998.724024
BibTeX | RIS
J. Strassner, W. Heiden:
Encountering virtual Worlds - State-of-the-art Report Virtual Environments.
BibTeX | RIS
M. Göbel, B. Fröhlich, G. Wesche, J. Wind, W. Heiden, F. Hasenbrink:
Virtuelle Umgebungen zur Visualisierung und Kooperation im Ingenieurbereich.
BibTeX | RIS
G. Eckel, M. Göbel, F. Hasenbrink, W. Heiden, U. Lechner, H. Tramberend, G. Wesche, J. Wind:
Benches and Caves.
BibTeX | RIS
Ralf Zimmer, Marko Wöhler, Ralf Thiele:
New scoring schemes for protein fold recognition based on Voronoi contacts.
doi:10.1093/bioinformatics/14.3.295 PMID
BibTeX | RIS
1997
Marcus Müller, Jean W.T. Smolders, Angela M. Meyer zum Gottesberge, Alexander Reuter, Ralf M. Zwacka, Hans Weiher, Rainer Klinke:
Loss of auditory function in transgenic Mpv17-deficient mice.
doi:10.1016/S0378-5955(97)00175-5 PMID
BibTeX | RIS
Marco Di Fruscio, Hans Weiher, Barbara C. Vanderhyden, Takashi Imai, Tadahiro Shiomi, Tada-Aki Hori, Rudolf Jaenisch, Douglas A. Gray:
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.
doi:10.1128/MCB.17.7.4080 PMID
BibTeX | RIS
Jörn Oliver Sass, Bernd Zimmermann, Ralph Rühl, Heinz Nau:
Effects of all-trans-retinoyl-beta-D-glucuronide and all-trans-retinoic acid on chondrogenesis and retinoid metabolism in mouse limb bud mesenchymal cells in vitro.
doi:10.1007/s002040050368 PMID
BibTeX | RIS
Jörn Oliver Sass, Georg Tzimas, Heinz Nau:
9,13-Dicis-retinoic acid as an isomerization product of 9-cis-retinoic acid.
PMID URL
BibTeX | RIS
Jörn Oliver Sass, Wolf Endres:
Quantitation of total homocysteine in human plasma by derivatization to its N(O,S)-propoxycarbonyl propyl ester and gas chromatography-mass spectrometry analysis.
doi:10.1016/S0378-4347(97)00080-7 PMID
BibTeX | RIS
Richard Jäger, Ute Herzer, Johannes Schenkel, Hans Weiher:
Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice.
doi:10.1038/sj.onc.1201353
BibTeX | RIS
Manfred Kaul, Wolfgang Heiden:
Internationale Kooperation in der Medienkommunikation.
BibTeX | RIS
Manfred Kaul, Wolfgang Heiden:
Der virtuelle Wetterfrosch.
BibTeX | RIS
G. Wesche, J. Wind, W. Heiden, F. Hasenbrink, M. Göbel:
Engineering on the Responsive Workbench.
BibTeX | RIS
Wolfgang Heiden:
Erfahrungen mit Virtuellen Studios und Verteilter Video-Produktion.
BibTeX | RIS
Wolfgang Heiden:
Distributed Video Production - ACTS Project DVP.
BibTeX | RIS
M. Fleischmann, T. Sikora, W. Heiden, W. Strauss, K. Sikora, J. Speier:
Virtual Balance: an input device for VR environments.
BibTeX | RIS
G. Eckel, M. Göbel, F. Hasenbrink, W. Heiden, U. Lechner, H. Tramberend, G. Wesche, J. Wind:
Benches and CAVEs.
BibTeX | RIS
Ralf Zimmer, Ralf Thiele:
Fast protein fold recognition and accurate sequence-structure alignment.
doi:10.1007/BFb0033212
BibTeX | RIS
1996
A. M. Meyer zum Gottesberge, A. Reuter, H. Weiher:
Inner ear defect similar to Alport's syndrome in the glomerulosclerosis mouse model Mpv17.
doi:10.1007/BF00179952 PMID
BibTeX | RIS
B. Hartenstein, J. Schenkel, J. Kuhse, B. Besenbeck, C. Kling, C. M. Becker, H. Betz, H. Weiher:
Low level expression of glycine receptor beta subunit transgene is sufficient for phenotype correction in spastic mice.
doi:10.1002/j.1460-2075.1996.tb00469.x PMID
BibTeX | RIS
J. O. Sass, E. Masgrau, P. A. Piletta, H. Nau, J. H. Saurat:
Plasma retinoids after topical use of retinaldehyde on human skin.
doi:10.1159/000211436 PMID
BibTeX | RIS
J. O. Sass, L. Didierjean, P. Carraux, C. Plum, H. Nau, J. H. Saurat:
Metabolism of topical retinaldehyde and retinol by mouse skin in vivo: predominant formation of retinyl esters and identification of 14-hydroxy-4, 14-retro-retinol.
doi:10.1111/j.1600-0625.1996.tb00128.x PMID
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H. Nau, M. M. Elmazar, R. Rühl, R. Thiel, J. O. Sass:
All-trans-retinoyl-beta-glucuronide is a potent teratogen in the mouse because of extensive metabolism to all-trans-retinoic acid.
doi:10.1002/(SICI)1096-9926(199609)54:3<150::AID-TERA5>3.0.CO;2-7 PMID
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M. Foerster, J. O. Sass, R. Rühl, H. Nau:
Comparative studies on effects of all-trans-retinoic acid and all-trans-retinoyl-beta-d-glucuronide on the development of foetal mouse thymus in an organ culture system.
doi:10.1016/0887-2333(95)00094-1 PMID
BibTeX | RIS
Liliane Didierjean, Pierre Carraux, Denise Grand, Jörn Oliver Sass, Heinz Nau, Jean-Hilaire Saurat:
Topical retinaldehyde increases skin content of retinoic acid and exerts biologic activity in mouse skin.
doi:10.1111/1523-1747.ep12365603 PMID
BibTeX | RIS
Robin C. Humphreys, Maryla Krajewska, Susanne Krnacik, Richard Jäger, Hans Weiher, Stanislaw Krajewski, John C. Reed, Jeffrey M. Rosen:
Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis.
PMID doi:10.1242/dev.122.12.4013
BibTeX | RIS
Marina Schorpp, Richard Jäger, Karl Schellander, Johannes Schenkel, Erwin F. Wagner, Hans Weiher, Peter Angel:
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.
doi:10.1093/nar/24.9.1787 PMID
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Manfred Kaul, Christian Breiteneder, Simon Gibbs, Wolfgang Heiden, Dirk Steinberg, Markus Wasserschaff:
Distributed Video Production over ATM.
BibTeX | RIS
Manfred Kaul, Wolfgang Heiden:
Distributed Video Production.
URL
BibTeX | RIS
Christian Breiteneder, Simon Gibbs, Wolfgang Heiden, Manfred Kaul, Karl Jonas, Dirk Steinberg:
ATM virtual studio services.
BibTeX | RIS
T. Lengauer, R. Thiele, R. Zimmer:
Modellierung von Proteinstrukturen.
BibTeX | RIS
1995
Johannes Schenkel, Ralf Michael Zwacka, Christiane Rutenberg, Alexander Reuter, Rüdiger Waldherr, Hans Weiher:
Functional rescue of the glomerulosclerosis phenotype in Mpv17 mice by transgenesis with the human Mpv17 homologue.
doi:10.1038/ki.1995.270 PMID
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Sabine Gack, Rudiger Vallon, Jorg Schmidt, Agamemnon Grigoriadis, Jan Tuckermann, Johannes Schenkel, Hans Weiher, Erwin F. Wagner, Peter Angel:
Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes.
URL PMID
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J. O. Sass, J. Hartmann, I. Chahoud, B. Shroot, H. Nau:
Transplacental pharmacokinetics of a synthetic retinoid which is not bound by mouse embryonic cellular retinoic acid-binding protein.
doi:10.1016/0378-4274(94)03175-7 PMID
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J. Brickman, W. Heiden, H. Vollhardt, C.-D. Zachmann:
New man-machine communication strategies in molecular modelling.
doi:10.1109/HICSS.1995.375329
BibTeX | RIS
G. Moeckel, B. Spiegelhalder, H. Bartsch, W. Heiden, J. Brickmann:
Substrate model for the activation of nitrosamines by cytochrome P450.
doi:10.1007/BF02572023
BibTeX | RIS
Bernd Fröhlich, Wolfgang Heiden, Wolfgang Krüger, Gerold Wesche:
Molecular Modelling on the Responsive Workbench.
URL
BibTeX | RIS
J. Brickmann, T. Goetze, W. Heiden, G. Moeckel, S. Reiling, H. Vollhardt, C.-D. Zachmann:
Interactive Visualization of Molecular Scenarios with MOLCAD/SYBYL.
BibTeX | RIS
Ralf Thiele, Ralf Zimmer, Thomas Lengauer:
Recursive Dynamic Programming for Adaptive Sequence and Structure Alignment.
PMID
BibTeX | RIS
H. Schmidt, D. Theune, R. Thiele, T. Lengauer:
EMC-driven midway routing on PCBs.
doi:10.1109/EDTC.1995.470357
BibTeX | RIS
1994
R. M. Zwacka, A. Reuter, E. Pfaff, J. Moll, K. Gorgas, M. Karasawa, H. Weiher:
The glomerulosclerosis gene Mpv17 encodes a peroxisomal protein producing reactive oxygen species.
doi:10.1002/j.1460-2075.1994.tb06842.x PMID
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G. Tzimas, J. O. Sass, W. Wittfoht, M. M. Elmazar, K. Ehlers, H. Nau:
Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos.
URL PMID
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William J. Scott Jr., Rosemarie Walter, Georg Tzimas, Jörn Oliver Sass, Heinz Nau, Michael D. Collins:
Endogenous Status of Retinoids and Their Cytosolic Binding Proteins in Limb Buds of Chick vs Mouse Embryos.
doi:10.1006/dbio.1994.1262 PMID
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Jörn Oliver Sass, Georg Tzimas, Heinz Nau:
9-cis-retinoyl-beta-D-glucuronide is a major metabolite of 9-cis-retinoic acid.
doi:10.1016/0024-3205(94)00703-9 PMID
BibTeX | RIS
Jörn Oliver Sass, Heinz Nau:
Single-run analysis of isomers of retinoyl-β-D-glucuronide and retinoic acid by reversed-phase high-performance liquid chromatography.
doi:10.1016/0021-9673(94)00829-9 PMID
BibTeX | RIS
J. O. Sass, A. Forster, K. W. Bock, H. Nau:
Glucuronidation and isomerization of all-trans- and 13-cis-retinoic acid by liver microsomes of phenobarbital- or 3-methylcholanthrene-treated rats.
doi:10.1016/0006-2952(94)90179-1 PMID
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Jörn Oliver Sass:
3,4-Didehydroretinol may be present in human embryos/fetuses.
doi:10.1016/0890-6238(94)90024-8 PMID
BibTeX | RIS
J. Brickmann, W. Heiden:
Zurück zur Natur - Metamorphose einer Industrielandschaft.
BibTeX | RIS
Paul Pixner, Wolfgang Heiden, Hendrik Merx, Gerd Moeckel, Andreas Möller, Jürgen Brickmann:
Empirical Method for the Quantification and Localization of Molecular Hydrophobicity.
doi:10.1021/ci00022a013
BibTeX | RIS
Wolfgang Heiden, Jürgen Brickmann:
Segmentation of protein surfaces using fuzzy logic.
doi:10.1016/0263-7855(94)80075-8 PMID
BibTeX | RIS
H. Mevissen, R. Thiele, R. Zimmer, T. Lengauer:
The ToPLign Software Environment - Toolbox for Preotein Alignment.
BibTeX | RIS
D. Theune, R. Thiele, W. John, T. Lengauer:
Robust methods for EMC-driven routing.
doi:10.1109/43.329265
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1993
Hans Weiher:
Glomerular sclerosis in transgenic mice: the Mpv-17 gene and its human homologue.
PMID
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M. Karasawa, R. M. Zwacka, A. Reuter, T. Fink, C. L. Hsieh, P. Lichter, U. Francke, H. Weiher:
The human homolog of the glomerulosclerosis gene Mpv17: structure and genomic organization.
doi:10.1093/hmg/2.11.1829 PMID
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Wolfgang Heiden:
Methoden zur computerunterstützten Untersuchung selektiver Oberflächeneigenschaften von Proteinen.
BibTeX | RIS
Wolfgang Heiden, Gerd Moeckel, J. Brickmann:
A new approach to analysis and display of local lipophilicity/hydrophilicity mapped on molecular surfaces.
doi:10.1007/BF00124359 PMID
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W. Heiden, T. Goetze, J. Brickmann:
Interaktive Berechnung, Darstellung und Klassifizierung von molekularen Oberflächen.
BibTeX | RIS
W. Heiden, T. Goetze, J. Brickmann:
Fast generation of molecular surfaces from 3D data fields with an enhanced "marching cube" algorithm.
doi:10.1002/jcc.540140212
BibTeX | RIS
W. John, D. Theune, R. Thiele:
Layout design for printed-circuit boards under EMC-constraints.
BibTeX | RIS
1992
Carl-Dieter Zachmann, Wolfgang Heiden, Micheal Schlenkrich, Jürgen Brickmann:
Topological analysis of complex molecular surfaces.
doi:10.1002/jcc.540130110
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Dirk Theune, Ralf Thiele, Thomas Lengauer, Anja Feldmann:
HERO: Hierarchical EMC-constrained routing.
doi:10.1109/ICCAD.1992.279326
BibTeX | RIS
1991
G. Moeckel, B. Spiegelhalder, R. Preussmann, W. Heiden, M. Waldherr-Teschner, J. Brickmann:
Investigation of N-Nitrosamine Structure-Activity Relationship Applying Molecular Modelling and ab-initio Calculations.
doi:10.1007/BF01625409
BibTeX | RIS
W. Heiden, T. Goetze, J. Brickmann:
"Marching Cube"-Algorithmen zur schnellen Generierung von Isoflächen auf der Basis dreidimensionaler Datenfelder.
doi:10.1007/978-3-642-76780-7_7
BibTeX | RIS
1990
Hans Weiher, Tetsuo Noda, Douglas A. Gray, Arlene H. Sharpe, Rudolf Jaenisch:
Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome.
doi:10.1016/0092-8674(90)90008-3 PMID
BibTeX | RIS
W. Heiden, T. Goetze, J. Brickmann:
Marching Cube Algorithms for Fast Generation of Isosurfaces on the Basis of 3D-Data Fields.
BibTeX | RIS
Wolfgang Heiden, Michael Schlenkrich, Jürgen Brickmann:
Triangulation algorithms for the representation of molecular surface properties.
doi:10.1007/BF00125014
BibTeX | RIS
W. Heiden, M. Schlenkrich, C.-D. Zachmann, J. Brickmann:
Triangulation of Molecular Surfaces.
doi:10.1007/978-3-642-75430-2_13
BibTeX | RIS
1988
W. Michael Arnold, Ulrich Zimmermann, Wolfgang Heiden, Jan Ahlers:
The influence of tetraphenylborates (hydrophobic anions) on yeast cell electro-rotation.
doi:10.1016/0005-2736(88)90278-7 PMID
BibTeX | RIS
1987
H. Weiher, E. Barklis, W. Ostertag, R. Jaenisch:
Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells.
PMID doi:10.1128/jvi.61.9.2742-2746.1987
BibTeX | RIS
H. Rohdewohld, H. Weiher, W. Reik, R. Jaenisch, M. Breindl:
Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites.
PMID doi:10.1128/jvi.61.2.336-343.1987
BibTeX | RIS
1985
W. Reik, H. Weiher, R. Jaenisch:
Replication-competent Moloney murine leukemia virus carrying a bacterial suppressor tRNA gene: selective cloning of proviral and flanking host sequences.
doi:10.1073/pnas.82.4.1141 PMID
BibTeX | RIS
1984
H. Weiher, M. R. Botchan:
An enhancer sequence from bovine papilloma virus DNA consists of two essential regions.
doi:10.1093/nar/12.6.2901 PMID
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Alain Sergeant, Dirk Bohmann, Hanswalter Zentgraf, Hans Weiher, Walter Keller:
A transcription enhancer acts in vitro over distances of hundreds of base-pairs on both circular and linear templates but not on chromatin-reconstituted DNA.
doi:10.1016/0022-2836(84)90028-7 PMID
BibTeX | RIS
M. Nunn, H. Weiher, P. Bullock, P. Duesberg:
Avian erythroblastosis virus E26: nucleotide sequence of the tripartite onc gene and of the LTR, and analysis of the cellular prototype of the viral ets sequence.
doi:10.1016/0042-6822(84)90378-7 PMID
BibTeX | RIS
1983
H. Weiher, M. Konig, P. Gruss:
Multiple point mutations affecting the simian virus 40 enhancer.
doi:10.1126/science.6297005 PMID
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M. Lusky, L. Berg, H. Weiher, M. Botchan:
Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit.
doi:10.1128/mcb.3.6.1108-1122.1983 PMID
BibTeX | RIS
1982
Hans Weiher, Heinz Schaller:
Segment-specific mutagenesis: extensive mutagenesis of a lac promoter/operator element.
doi:10.1073/pnas.79.5.1408 PMID
BibTeX | RIS